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pro vyhledávání: '"Ryohchi Suzuki"'
Autor:
Takenori Ishizawa, Koichi Takahashi, Kentaro Asanuma, Shigeo Sato, Kenji Nohmi, Ryohchi Suzuki, Tadashi Morikawa, Tomoyuki Watanabe, Yoshinobu Higuchi, Akie Homma, Tatsuya Tamura, Makoto Kanda, Noriyuki Izutani, Takashi Emura, Kazuaki Maeda, Hironoshin Kitagawa, Haruhiko Sato, Tadao Yamazaki, Masahisa Ikemi, Hitoshi Ikeya, Tetsu Matsuura, Tatsuya Kato, Akira Okamachi, Hidetomo Kitamura
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:1062-1075
We previously reported that a conjugate of hyaluronic acid (HA) and methotrexate (MTX) could be a prototype for future osteoarthritis drugs having the efficacy of the two clinically validated agents but with a reduced risk of the systemic side effect