Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ryo Yonehara"'
Autor:
Kenta Tsutsumi, Ryo Yonehara, Etsuko Ishizaka-Ikeda, Naoyuki Miyazaki, Shintaro Maeda, Kenji Iwasaki, Atsushi Nakagawa, Eiki Yamashita
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-10 (2019)
In Pseudomonas aeruginosa, MexAB–OprM plays a central role in multidrug resistance by ejecting various drug compounds. Here the authors present the structure of wild-type MexAB–OprM in the presence or absence of drugs and propose mechanisms for c
Externí odkaz:
https://doaj.org/article/cc7f1952c6e7489598ccf9dab7aef02c
Autor:
Taihei Murakami, Shigefumi Kumachi, Yasuhiro Matsunaga, Miwa Sato, Kanako Wakabayashi-Nakao, Hidekazu Masaki, Ryo Yonehara, Maiko Motohashi, Naoto Nemoto, Masayuki Tsuchiya
Publikováno v:
Antibodies, Vol 11, Iss 1, p 10 (2022)
A variable domain of heavy chain antibody (VHH) has different binding properties than conventional antibodies. Conventional antibodies prefer binding to the convex portion of the antigen, whereas VHHs prefer epitopes, such as crevices and clefts on t
Externí odkaz:
https://doaj.org/article/0eaaa057c8d54340a2f83097ac55147a
Autor:
Ryo Yonehara, Shigeyuki Nada, Tomokazu Nakai, Masahiro Nakai, Ayaka Kitamura, Akira Ogawa, Hirokazu Nakatsumi, Keiichi I. Nakayama, Songling Li, Daron M. Standley, Eiki Yamashita, Atsushi Nakagawa, Masato Okada
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
mTORC1 activity is controlled through Rag GTPases, which are anchored to the lysosome through the Ragulator. Here, the authors give molecular insights into Ragulator-Rag GTPase assembly and present the crystal structures of the Ragulator alone and in
Externí odkaz:
https://doaj.org/article/482ae068892c43919082fb767f0bf703
Autor:
Ryo Yonehara, Shigefumi Kumachi, Kenji Kashiwagi, Kanako Wakabayashi-Nakao, Maiko Motohashi, Taihei Murakami, Teruhiko Yanagisawa, Hidenao Arai, Akikazu Murakami, Yukio Ueno, Naoto Nemoto, Masayuki Tsuchiya
Publikováno v:
The Journal of biological chemistry.
Fibroblast growth factor (FGF) is a multifunctional protein that exhibits a wide range of biological effects. Most commonly, it acts as a mitogen, but it also has regulatory, morphological, and endocrine effects. The four receptor subtypes of FGF are
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbb5817fcd758852bed35537c2acb59c
https://pubmed.ncbi.nlm.nih.gov/36529290
https://pubmed.ncbi.nlm.nih.gov/36529290
Autor:
Taihei Murakami, Shigefumi Kumachi, Yasuhiro Matsunaga, Miwa Sato, Kanako Wakabayashi-Nakao, Hidekazu Masaki, Ryo Yonehara, Maiko Motohashi, Naoto Nemoto, Masayuki Tsuchiya
Publikováno v:
Antibodies; Volume 11; Issue 1; Pages: 10
A variable domain of heavy chain antibody (VHH) has different binding properties than conventional antibodies. Conventional antibodies prefer binding to the convex portion of the antigen, whereas VHHs prefer epitopes, such as crevices and clefts on t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f04502ecc5c566a681972c024f8c023b
https://pubmed.ncbi.nlm.nih.gov/35225868
https://pubmed.ncbi.nlm.nih.gov/35225868
Autor:
Ryo Yonehara1 yonehara@epsilon-mol.co.jp, Shigefumi Kumachi1, Kenji Kashiwagi2, Kanako Wakabayashi-Nakao1, Maiko Motohashi1, Taihei Murakami1, Teruhiko Yanagisawa2, Hidenao Arai1, Akikazu Murakami3, Yukio Ueno2, Naoto Nemoto1, Masayuki Tsuchiya1 tsuchiya@epsilon-mol.co.jp
Publikováno v:
Journal of Biological Chemistry. Feb2023, Vol. 299 Issue 2, p1-11. 11p.
Publikováno v:
Proteins: Structure, Function, and Bioinformatics. 84:759-769
The genome of Pseudomonas aeruginosa encodes tripartite efflux pumps that extrude functionally and structurally dissimilar antibiotics from the bacterial cell. MexAB-OprM, MexCD-OprJ, MexEF-OprN, and MexXY-OprM are the main tripartite efflux pumps re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::bb0cb764d9135d8554546761fb91f43d
https://doi.org/10.1002/prot.25022
https://doi.org/10.1002/prot.25022
Autor:
Eiki Yamashita, Tomokazu Nakai, Masato Okada, Songling Li, Hirokazu Nakatsumi, Shigeyuki Nada, Daron M. Standley, Atsushi Nakagawa, M. Nakai, Keiichi I. Nakayama, Ryo Yonehara, Akira Ogawa, Ayaka Kitamura
Publikováno v:
Nature Communications, Vol 8, Iss 1, Pp 1-11 (2017)
Nature Communications
Nature Communications
The mechanistic target of rapamycin complex 1 (mTORC1) plays a central role in regulating cell growth and metabolism by responding to cellular nutrient conditions. The activity of mTORC1 is controlled by Rag GTPases, which are anchored to lysosomes v
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ab3d6f579b05cc6803de5e50c6c6d31
https://doi.org/10.1038/s41467-017-01762-3
https://doi.org/10.1038/s41467-017-01762-3
Publikováno v:
Proteins. 84(6)
The genome of Pseudomonas aeruginosa encodes tripartite efflux pumps that extrude functionally and structurally dissimilar antibiotics from the bacterial cell. MexAB-OprM, MexCD-OprJ, MexEF-OprN, and MexXY-OprM are the main tripartite efflux pumps re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::ebafde0729c8ee590099052e572fc7dd
https://pubmed.ncbi.nlm.nih.gov/26914226
https://pubmed.ncbi.nlm.nih.gov/26914226
Autor:
Taiji Nakae, N. Sato, S. Murakami, Takanori Matsuura, K. Harada, E. Yamashita, Atsushi Nakagawa, Ryo Yonehara
Publikováno v:
Acta Crystallographica Section A Foundations of Crystallography. 67:C744-C744
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::22ff7127fa205f2fb614bc321ac22600
https://doi.org/10.1107/s0108767311081220
https://doi.org/10.1107/s0108767311081220