Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ryo Tanifuji"'
Autor:
Ryo Tanifuji, Hiroki Oguri
Publikováno v:
Beilstein Journal of Organic Chemistry, Vol 20, Iss 1, Pp 1693-1712 (2024)
A steadily increasing number of reports have been published on chemo-enzymatic synthesis methods that integrate biosynthetic enzymatic transformations with chemical conversions. This review focuses on the total synthesis of natural products and class
Externí odkaz:
https://doaj.org/article/0dac186e54de40f08f80c887f85223b8
Publikováno v:
Tetrahedron Chem, Vol 1, Iss , Pp 100010- (2022)
Chemo-enzymatic hybrid process merging enzymatic cascade reactions of designed substrates with chemo- and site-selective synthetic manipulations allowed the chemo-enzymatic total syntheses of jorunnamycin A and saframycin A, in just 4 and 5 pots proc
Externí odkaz:
https://doaj.org/article/e22ed92458ef4d5c93cca856ac4db42a
Publikováno v:
Natural Product Reports. 37:1098-1121
Covering: 2000 to 2019Rapid access to genomic data has facilitated the identification of the biosynthetic enzyme genes of alkaloid natural products and elucidation of their biosynthetic pathways. Enzymes for the rapid construction of molecular scaffo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9da75412bfc2c618934a218d21158afe
https://doi.org/10.1039/c9np00073a
https://doi.org/10.1039/c9np00073a
Autor:
Ryo Tanifuji
Publikováno v:
Journal of Synthetic Organic Chemistry, Japan. 80:778-779
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ce4dd35ec67eb955c9458d29d2df0a61
https://doi.org/10.5059/yukigoseikyokaishi.80.778
https://doi.org/10.5059/yukigoseikyokaishi.80.778
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 29:1807-1811
C5-desoxy analogs of tetrahydroisoquinoline (THIQ) alkaloids were designed and synthesized as hitherto unexplored structural variants for evaluation of their DNA alkylating activities. While chemical synthesis of the C5-desoxy analogs bearing a pheno
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9ac2aa19e12d0e18765c9edaf308b3f9
https://doi.org/10.1016/j.bmcl.2019.05.009
https://doi.org/10.1016/j.bmcl.2019.05.009
Autor:
Ryo Tanifuji, Ryutaro Asano, Hiroki Oguri, Kento Koketsu, Michiko Takakura, Hideaki Oikawa, Atsushi Minami
Publikováno v:
Journal of the American Chemical Society. 140:10705-10709
The antitumor tetrahydroisoquinoline (THIQ) alkaloids share a common pentacyclic scaffold that is biosynthesized by nonribosomal peptide synthetases involving unique enzymatic Pictet-Spengler cyclizations. Herein we report concise and divergent chemo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::dd55d42b68b0ec961f11d794955eaad5
https://doi.org/10.1021/jacs.8b07161
https://doi.org/10.1021/jacs.8b07161
Publikováno v:
Tetrahedron Letters. 57:623-626
Biosynthetic assembly lines of tetrahydroisoquinoline alkaloids employ the tyrosine derivative, ( S )-2-amino-3-(3-hydroxy-4-methoxy-5-methylphenyl)propanoic acid, as a common amino acid building block. A catalytic asymmetric synthetic route to the c
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c6ec5c62b23ec87727e5fafd1a57b9ff
https://doi.org/10.1016/j.tetlet.2015.12.110
https://doi.org/10.1016/j.tetlet.2015.12.110