Zobrazeno 1 - 10
of 42
pro vyhledávání: '"Ryo Nakamichi"'
Autor:
Ryo Nakamichi, Taichi Saito, Yasunori Shimamura, Masanori Hamada, Keiichiro Nishida, Toshifumi Ozaki
Publikováno v:
BMC Musculoskeletal Disorders, Vol 25, Iss 1, Pp 1-8 (2024)
Abstract Background The purpose of this study was to examine two techniques for Carpal Tunnel Syndrome, mini-Open Carpal Tunnel Release (mini-OCTR) and Endoscopic Carpal Tunnel Release (ECTR), to compare their therapeutic efficacy. Methods Sixteen pa
Externí odkaz:
https://doaj.org/article/dfab71042fa54d0880567907abe8a1b9
Autor:
Ryo Nakamichi, Hiroshi Asahara
Publikováno v:
Bio-Protocol, Vol 12, Iss 21 (2022)
When focusing on quick movements in the analysis of animal behavior, a high-speed camera can be used as a powerful tool. There are many options for high-speed cameras to record movement. In recent years, the quality and sophistication of videos captu
Externí odkaz:
https://doaj.org/article/21ecb68ed79246dda9aabdf4a5dc3b57
Autor:
Yoshiaki Ito, Tokio Matsuzaki, Fumiaki Ayabe, Sho Mokuda, Ryota Kurimoto, Takahide Matsushima, Yusuke Tabata, Maiko Inotsume, Hiroki Tsutsumi, Lin Liu, Masahiro Shinohara, Yoko Tanaka, Ryo Nakamichi, Keiichiro Nishida, Martin K. Lotz, Hiroshi Asahara
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-13 (2021)
Osteoarthritis is caused by an imbalance between extracellular matrix synthesis and degradation. Here, the authors show that both strands of microRNA-455, -5p and -3p, target HIF2α and regulate cartilage homeostasis, and show that overexpression of
Externí odkaz:
https://doaj.org/article/f8166b7edfce46f19f52746332d9254e
Autor:
Kaho Takada, Tomoki Chiba, Takayuki Miyazaki, Lisa Yagasaki, Ryo Nakamichi, Takanori Iwata, Keiji Moriyama, Hiroyuki Harada, Hiroshi Asahara
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The periodontal ligament (PDL) comprises a fibrous tissue that connects teeth to alveolar bone and is essential for periodontal function. The transcription factor mohawk homeobox (Mkx) is expressed in the PDL where it plays an important role in the d
Externí odkaz:
https://doaj.org/article/c15c64b8d7d54ef99477e2dc4a9bf5c7
Autor:
Hiroki Tsutsumi, Ryota Kurimoto, Ryo Nakamichi, Tomoki Chiba, Takahide Matsushima, Yuta Fujii, Risa Sanada, Tomomi Kato, Kana Shishido, Yuriko Sakamaki, Tsuyoshi Kimura, Akio Kishida, Hiroshi Asahara
Publikováno v:
Journal of Tissue Engineering, Vol 13 (2022)
Tendons and ligaments are essential connective tissues that connect the muscle and bone. Their recovery from injuries is known to be poor, highlighting the crucial need for an effective therapy. A few reports have described the development of artific
Externí odkaz:
https://doaj.org/article/8a19bcd27337489aa78fffa7de09e233
Autor:
Sho Mokuda, Ryo Nakamichi, Tokio Matsuzaki, Yoshiaki Ito, Tempei Sato, Kohei Miyata, Masafumi Inui, Merissa Olmer, Eiji Sugiyama, Martin Lotz, Hiroshi Asahara
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Wwp2 is an HECT-type E3 ubiquitin ligase abundantly expressed in articular cartilage. Here, the authors show that in mice, loss of Wwp2 leads to upregulated Runx2-Adamts5 signaling in articular cartilage and development of osteoarthritis, and that di
Externí odkaz:
https://doaj.org/article/6d3f9987d5c04d849d14252ac998b87e
Autor:
Kensuke Kataoka, Ryota Kurimoto, Hiroki Tsutsumi, Tomoki Chiba, Tomomi Kato, Kana Shishido, Mariko Kato, Yoshiaki Ito, Yuichiro Cho, Osamu Hoshi, Ayako Mimata, Yuriko Sakamaki, Ryo Nakamichi, Martin K. Lotz, Keiji Naruse, Hiroshi Asahara
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 8 (2020)
Tendons and ligaments are pivotal connective tissues that tightly connect muscle and bone. In this study, we developed a novel approach to generate tendon/ligament-like tissues with a hierarchical structure, by introducing the tendon/ligament-specifi
Externí odkaz:
https://doaj.org/article/20e44cb8d8ce4a15883916e45a651b9d
Autor:
Ryo Nakamichi, Hiroshi Asahara
Publikováno v:
JOR Spine, Vol 3, Iss 1, Pp n/a-n/a (2020)
Abstract Damage to the intervertebral discs (IVDs) occurs due to aging or excessive mechanical stress, causing a series of IVD‐related degenerative diseases, such as spinal disc herniation and spondylosis. These IVD‐related diseases are difficult
Externí odkaz:
https://doaj.org/article/d5a108f63fb846e8940d8cdbffdf38b9
Autor:
Ryo Nakamichi, Yoshiaki Ito, Masafumi Inui, Naoko Onizuka, Tomohiro Kayama, Kensuke Kataoka, Hidetsugu Suzuki, Masaki Mori, Masayo Inagawa, Shizuko Ichinose, Martin K. Lotz, Daisuke Sakai, Koichi Masuda, Toshifumi Ozaki, Hiroshi Asahara
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Homeobox protein Mohwak (Mkx) is involved in tendon and ligament development. Here the authors show that Mkx in the outer annulus fibrosus of the intervertebral disc plays a role in maintenance of the IVD, showing that stem cells overexpressing Mkx e
Externí odkaz:
https://doaj.org/article/1ae218da6e53457ca91ea8cbde500126
Autor:
Takayuki Furumatsu, Keiichiro Nishida, M. Matsuhashi, Yasunori Shimamura, Aki Yoshida, Taichi Saito, Toshifumi Ozaki, Takaaki Hiranaka, Yuki Okazaki, Ryo Nakamichi, Satoshi Nezu
Publikováno v:
Journal of Orthopaedic Research. 40:1872-1882
Tendons and ligaments are jointed to bones via an enthesis that is essential to the proper function of the muscular and skeletal structures. The aim of the study is to investigate the effect of mechanical stress on the enthesis. We used ex vivo model