Zobrazeno 1 - 10
of 49
pro vyhledávání: '"Ryo Higuchi‐Sanabria"'
Publikováno v:
Clinical and Translational Discovery, Vol 4, Iss 2, Pp n/a-n/a (2024)
Abstract Ultraviolet (UV) radiation, a component of sunlight, holds both advantageous anddetrimental effects on human health. While shorter wavelengths of UV radiationaid in melanin and vitamin D synthesis, longer wavelengths pose risks like skincanc
Externí odkaz:
https://doaj.org/article/2f548560be7248858ba1ee88555b08f7
Autor:
Gilberto Garcia, Hanlin Zhang, Sophia Moreno, C Kimberly Tsui, Brant Michael Webster, Ryo Higuchi-Sanabria, Andrew Dillin
Publikováno v:
eLife, Vol 12 (2023)
Changes in lipid metabolism are associated with aging and age-related diseases, including proteopathies. The endoplasmic reticulum (ER) is uniquely a major hub for protein and lipid synthesis, making its function essential for both protein and lipid
Externí odkaz:
https://doaj.org/article/5e95a91e959d4c208e51fa18a332f91e
Autor:
Cierra N. Sing, Enrique J. Garcia, Thomas G. Lipkin, Thomas M. Huckaba, Catherine A. Tsang, Arielle C. Coughlin, Emily J. Yang, Istvan R. Boldogh, Ryo Higuchi-Sanabria, Liza A. Pon
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-12 (2022)
Actin cables affect lifespan by supporting movement and inheritance of fitter mitochondria to daughter cells in yeast. Here the authors show that branched-chain amino acid (BCAA) levels affect actin cable stability and a role for YKL075C/AAN1 in cont
Externí odkaz:
https://doaj.org/article/2db042e71dcf439baa40f994cc71d0c9
Autor:
Julea Vlassakis, Louise L. Hansen, Ryo Higuchi-Sanabria, Yun Zhou, C. Kimberly Tsui, Andrew Dillin, Haiyan Huang, Amy E. Herr
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-14 (2021)
Existing methods for multimeric protein complex quantification in single cells suffer from limited selectivity and sensitivity. Here the authors report Single-cell protein Interaction Fractionation Through Electrophoresis and immunoassay Readout (SIF
Externí odkaz:
https://doaj.org/article/b415092cbb764619a17faea6a93f2682
Autor:
Phillip A. Frankino, Talha F. Siddiqi, Theodore Bolas, Raz Bar-Ziv, Holly K. Gildea, Hanlin Zhang, Ryo Higuchi-Sanabria, Andrew Dillin
Publikováno v:
iScience, Vol 25, Iss 7, Pp 104571- (2022)
Summary: The deleterious potential to generate oxidative stress is a fundamental challenge to metabolism. The oxidative stress response transcription factor, SKN-1/NRF2, can sense and respond to changes in metabolic state, although the mechanism and
Externí odkaz:
https://doaj.org/article/b8b1723357a2408287e1e54de8221cc9
Publikováno v:
Frontiers in Aging, Vol 3 (2022)
Organisms are constantly exposed to stress both from the external environment and internally within the cell. To maintain cellular homeostasis under different environmental and physiological conditions, cell have adapted various stress response signa
Externí odkaz:
https://doaj.org/article/e3c22ff1b9014f2ab386c08c5ed80e42
Publikováno v:
Neural Regeneration Research, Vol 17, Iss 2, Pp 309-310 (2022)
Externí odkaz:
https://doaj.org/article/3eca06d12235495ea1a6374297518602
Publikováno v:
Microbial Cell, Vol 3, Iss 2, Pp 79-88 (2016)
Increasing the stability or dynamics of the actin cytoskeleton can extend lifespan in C. elegans and S. cerevisiae. Actin cables of budding yeast, bundles of actin filaments that mediate cargo transport, affect lifespan control through effects on mit
Externí odkaz:
https://doaj.org/article/fa966f0f6e284f95aef58a89a2d0d51c
Autor:
Ryo Higuchi-Sanabria, Enrique J Garcia, Delia Tomoiaga, Emilia L Munteanu, Paul Feinstein, Liza A Pon
Publikováno v:
PLoS ONE, Vol 11, Iss 1, p e0146120 (2016)
Saccharomyces cerevisiae are widely used for imaging fluorescently tagged protein fusions. Fluorescent proteins can easily be inserted into yeast genes at their chromosomal locus, by homologous recombination, for expression of tagged proteins at endo
Externí odkaz:
https://doaj.org/article/930ba0327c0546668de53cb5abf58bf9
Publikováno v:
Aging.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b6ddb7ff8be4b37e3b1d0df9ee84e15a
https://doi.org/10.18632/aging.204746
https://doi.org/10.18632/aging.204746