Zobrazeno 1 - 10
of 330
pro vyhledávání: '"Ryo, Yamasaki"'
Autor:
Ezgi Ozdemir Takase, Ryo Yamasaki, Satoshi Nagata, Mitsuru Watanabe, Katsuhisa Masaki, Hiroo Yamaguchi, Jun-ichi Kira, Hideyuki Takeuchi, Noriko Isobe
Publikováno v:
Scientific Reports, Vol 14, Iss 1, Pp 1-23 (2024)
Abstract In chronic stages of multiple sclerosis (MS) and its animal model, experimental autoimmune encephalitis (EAE), connexin (Cx)43 gap junction channel proteins are overexpressed because of astrogliosis. To elucidate the role of increased Cx43,
Externí odkaz:
https://doaj.org/article/677e0f459eba49d6aa9029b65a57d82b
Autor:
Eizo Tanaka, Ryo Yamasaki, Ban-yu Saitoh, Amina Abdelhadi, Satoshi Nagata, Sato Yoshidomi, Yuka Inoue, Koichiro Matsumoto, Jun-ichi Kira, Noriko Isobe
Publikováno v:
International Journal of Molecular Sciences, Vol 25, Iss 19, p 10464 (2024)
Autism spectrum disorder (ASD) is one of the most prevalent neurodevelopmental disorders. To explore its pathophysiology, we investigated the association between neonatal allergic exposure and behavioral changes. Adult female C57BL/6J mice were immun
Externí odkaz:
https://doaj.org/article/a1717a8804c54f869ce44517e54da36a
Autor:
Tomoki Uchikawa, Tetsuya Matoba, Takuro Kawahara, Isashi Baba, Shunsuke Katsuki, Jun-ichiro Koga, Yu Hashimoto, Ryo Yamasaki, Ikuyo Ichi, Hidetaka Akita, Hiroyuki Tsutsui
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-15 (2022)
Abstract Emerging evidence suggests that 7-ketocholesterol (7-KC), one of the most abundant dietary oxysterols, causes inflammation and cardiovascular diseases. Here we show the deteriorating effects of dietary 7-KC on myocardial ischemia–reperfusi
Externí odkaz:
https://doaj.org/article/1ffebf7ae76f430d94447418acaf13f1
Autor:
Ryo Yamasaki
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 23, p 16879 (2023)
Connexins (Cxs) form gap junctions through homotypic/heterotypic oligomerization. Cxs are initially synthesized in the endoplasmic reticulum, then assembled as hexamers in the Golgi apparatus before being integrated into the cell membrane as hemichan
Externí odkaz:
https://doaj.org/article/52caa7faa73c42a7966a863dab478ece
Autor:
Satoshi Nagata, Ryo Yamasaki, Ezgi Ozdemir Takase, Kotaro Iida, Mitsuru Watanabe, Katsuhisa Masaki, Marion Heleen Cathérine Wijering, Hiroo Yamaguchi, Jun-ichi Kira, Noriko Isobe
Publikováno v:
Biology, Vol 12, Iss 9, p 1217 (2023)
We previously reported a novel secondary progressive multiple sclerosis (SPMS) model, progressive experimental autoimmune encephalomyelitis (pEAE), in oligodendroglia-specific Cx47-inducible conditional knockout (Cx47 icKO) mice. Based on our prior s
Externí odkaz:
https://doaj.org/article/90bddc8b7a7146269bca5792f1f689bb
Autor:
Wataru Shiraishi, Ryo Yamasaki, Yu Hashimoto, Senri Ko, Yuko Kobayakawa, Noriko Isobe, Takuya Matsushita, Jun-ichi Kira
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-16 (2021)
Abstract Macrophages expressing C–C chemokine receptor type 2 (CCR2) infiltrate the central and peripheral neural tissues of amyotrophic lateral sclerosis (ALS) patients. To identify the functional role of CCR2+ macrophages in the pathomechanisms o
Externí odkaz:
https://doaj.org/article/38e6c8f790e142f19d800032a48c1af0
Autor:
Hayato Une, Ryo Yamasaki, Satoshi Nagata, Hiroo Yamaguchi, Yuko Nakamuta, Ulfa Camelia Indiasari, Yiwen Cui, Koji Shinoda, Katsuhisa Masaki, Magdalena Götz, Jun-ichi Kira
Publikováno v:
Journal of Neuroinflammation, Vol 18, Iss 1, Pp 1-19 (2021)
Abstract Background Brain astroglia are activated preceding the onset of experimental autoimmune encephalomyelitis (EAE), an animal model of multiple sclerosis (MS). We characterized the effects of brain astroglia on spinal cord inflammation, focusin
Externí odkaz:
https://doaj.org/article/37938b5b62a04f64beb4ea1d43370c05
Autor:
Hidenori Ogata, Xu Zhang, Saeko Inamizu, Ken‐ichiro Yamashita, Ryo Yamasaki, Takuya Matsushita, Noriko Isobe, Akio Hiwatashi, Shozo Tobimatsu, Jun‐ichi Kira
Publikováno v:
Annals of Clinical and Translational Neurology, Vol 7, Iss 11, Pp 2297-2309 (2020)
Abstract Objective To characterize the frequency and patterns of optic, trigeminal, and facial nerve involvement by neuroimaging and electrophysiology in IgG4 anti‐neurofascin 155 antibody‐positive (NF155+) chronic inflammatory demyelinating poly
Externí odkaz:
https://doaj.org/article/b8e0eecc967b4aef864dcd47de55a189
Autor:
Mitsuru Watanabe, Yuri Nakamura, Noriko Isobe, Masami Tanaka, Ayako Sakoda, Fumie Hayashi, Yuji Kawano, Ryo Yamasaki, Takuya Matsushita, Jun-ichi Kira
Publikováno v:
Journal of Neuroinflammation, Vol 17, Iss 1, Pp 1-10 (2020)
Abstract Background Progressive multifocal leukoencephalopathy (PML) caused by JC virus (JCV) is a rare but serious complication of some disease-modifying drugs used to treat multiple sclerosis (MS). Japanese MS patients treated with fingolimod were
Externí odkaz:
https://doaj.org/article/6a3b4e7e0e904e558051fa10c7c7f475
Autor:
Yu Hashimoto, Ryo Yamasaki, Senri Ko, Eriko Matsuo, Yuko Kobayakawa, Katsuhisa Masaki, Dai Matsuse, Noriko Isobe
Publikováno v:
International Journal of Molecular Sciences, Vol 23, Iss 24, p 16046 (2022)
Connexin 30 (Cx30), which forms gap junctions between astrocytes, regulates cell adhesion and migration, and modulates glutamate transport. Cx30 is upregulated on activated astroglia in central nervous system inflammatory lesions, including spinal co
Externí odkaz:
https://doaj.org/article/9c46d7f79a01481d9c283de359581a39