Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Ryo, Hanzawa"'
Autor:
Tohru Ohnuma, Tohru Nakamura, Yuto Takebayashi, Ryo Hanzawa, Maiko Kitazawa, Ryoko Higashiyama, Mayu Takeda, Katrin Thompson, Miwa Komatsu, Hiromi Shimazaki, Nobuto Shibata, Heii Arai
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 2, Iss 1, Pp 496-502 (2012)
Background/Aims: PiggyBac transposable element derived 1 (PGBD1) encodes a molecule involved in epigenetic mechanisms that have been implicated in Alzheimer’s disease (AD), and recent genome-wide association studies and meta-analyses have indicated
Externí odkaz:
https://doaj.org/article/8703d06e5ac0484191a653f5cbd09579
Autor:
Nobuto Shibata, Narimasa Katsuta, Yusuke Suzuki, Hitoshi Maeshima, Yasuhiko Tomino, Heii Arai, Ryoko Higashiyama, Tomohito Gohda, Motoyuki Higa, Shohei Nishimon, Toru Nakamura, Mayu Takeda, Yuri Hotta, Sho-ichi Yamagishi, Ryo Hanzawa, Yuto Takebayashi, Takahiro Sannohe, Masayoshi Takeuchi, Tohru Ohnuma
Publikováno v:
Neuroscience Letters. 593:51-55
Recent cross-sectional and longitudinal studies indicate that measurements of peripheral blood carbonyl stress markers such as the advanced glycation end product (AGE) pentosidine and the reactive carbonyl-detoxifying B6 vitamin pyridoxal could be us
Autor:
Mayu Takeda, Narimasa Katsuta, Ryo Hanzawa, Nobuto Shibata, Yuri Hotta, Heii Arai, Shohei Nishimon, Ryoko Higashiyama, Toru Nakamura, Hitoshi Maeshima, Tohru Ohnuma, Takahiro Sannohe, Motoyuki Higa, Yuto Takebayashi
Publikováno v:
Schizophrenia Bulletin. 40:1366-1373
Altered peripheral carbonyl stress markers, high levels of serum pentosidine, which accumulates following carbonyl stress, and low levels of pyridoxal (vitamin B6), which detoxifies reactive carbonyl compounds, have been reported in a cross-sectional
Autor:
Miwa Komatsu, Tohru Nakamura, Nobuto Shibata, Ryo Hanzawa, Heii Arai, Katrin Thompson, Maiko Kitazawa, Mayu Takeda, Tohru Ohnuma, Hiromi Shimazaki, Yuto Takebayashi, Ryoko Higashiyama
Publikováno v:
Dementia and Geriatric Cognitive Disorders Extra, Vol 2, Iss 1, Pp 496-502 (2012)
Dementia and Geriatric Cognitive Disorders EXTRA
Dementia and Geriatric Cognitive Disorders EXTRA
Background/Aims: PiggyBac transposable element derived 1 (PGBD1) encodes a molecule involved in epigenetic mechanisms that have been implicated in Alzheimer’s disease (AD), and recent genome-wide association studies and meta-analyses have indicated
Autor:
Nobuto Shibata, Motoyuki Higa, Narimasa Katsuta, Tohru Ohnuma, Heii Arai, Yuri Hotta, Ryo Hanzawa, Yuto Takebayashi, Yoshie Sakai, Hitoshi Maeshima, Maiko Kitazawa
Publikováno v:
The International Journal of Psychiatry in Medicine. 44:17-27
Objective: Disrupted glutamatergic neurotransmission and cognitive functions are key components in the pathophysiology of schizophrenia. Changes in levels of serum/plasma glutamatergic amino acids, such as glutamate, glycine, and L- and D-serine may
Autor:
Yuka Yasuda, Tohru Ohnuma, Branko Aleksic, Itaru Kushima, Nobuto Shibata, Nakao Iwata, Norio Ozaki, Heii Arai, Yuto Takebayashi, Ryoko Higashiyama, Hidenaga Yamamori, Masashi Ikeda, Ryo Hanzawa, Kenji Kondo, Ryota Hashimoto
Publikováno v:
American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics. (3)
Chromosome 22q11.2 deletion syndrome and genetic variations including single-nucleotide polymorphism (SNP) and copy number variation (CNV) in catechol-O-methyltransferase (COMT) situated at 22q11.2 remains controversial. Here, the genetic relationshi
Autor:
Yuto Takebayashi, Maiko Kitazawa, Yuri Hotta, Heii Arai, Motoyuki Higa, Ryo Hanzawa, Tohru Ohnuma, Nobuto Shibata, Tokiko Hatano, Hajime Baba, Hitoshi Maeshima
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 35:1965-1968
Disrupted glutamatergic neurotransmission may be a pathophysiological feature in the brains from patients with schizophrenia, and glutamatergic amino acids including D-serine have been found to be involved in pathophysiology. Endogenous and exogenous
Autor:
Maiko Kitazawa, Tokiko Hatano, Yasuhito Nagai, Tohru Ohnuma, Hajime Baba, Nobuto Shibata, Yuri Hotta, Hitoshi Maeshima, Yuto Takebayashi, Heii Arai, Ryo Hanzawa
Publikováno v:
Psychiatry and Clinical Neurosciences. 65:39-46
Aims: Schizophrenia is a major psychiatric disorder with complex genetic, environmental, and psychological causes, and oxidative stress may be involved in the pathogenesis of the disease. Glutathione (GSH), one of the main cellular non-protein antiox
Autor:
Yasuhito Nagai, Jun Karibe, Nobuto Shibata, Tokiko Hatano, Tohru Ohnuma, Hitoshi Maeshima, Ryo Hanzawa, Hajime Baba, Heii Arai
Publikováno v:
Neuroscience Letters. 463:223-227
Glutamatergic dysfunction may be a pathophysiological feature in the brains of schizophrenic patients. In addition to glutamate receptors, excitatory amino acid transporters (EAATs) have received much attention because they directly affect glutamater
Autor:
Heii Arai, Nobuto Shibata, Hitoshi Maeshima, Tokiko Hatano, Hajime Baba, Tohru Ohnuma, Ryo Hanzawa
Publikováno v:
Progress in Neuro-Psychopharmacology and Biological Psychiatry. 33:511-518
Differences in the levels of the glutamate-related amino acids glycine and serine in brain/plasma between schizophrenic patients and normal subjects and changes in the plasma concentrations of these amino acids according to the clinical course have b