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Targeting Bacterial Cell Wall Peptidoglycan Synthesis by Inhibition of Glycosyltransferase Activity.

Autor: Mesleh MF; Cubist Pharmaceuticals, a wholly-owned subsidiary of Merck & Co. Inc., 65 Hayden Avenue, Lexington, MA, 02421, USA., Rajaratnam P; Alchemia Limited, 3 Hi-Tech Court, Eight Mile Plains, Brisbane Technology Park, Qld, 4113, Australia., Conrad M; Cubist Pharmaceuticals, a wholly-owned subsidiary of Merck & Co. Inc., 65 Hayden Avenue, Lexington, MA, 02421, USA., Chandrasekaran V; Cubist Pharmaceuticals, a wholly-owned subsidiary of Merck & Co. Inc., 65 Hayden Avenue, Lexington, MA, 02421, USA., Liu CM; Cubist Pharmaceuticals, a wholly-owned subsidiary of Merck & Co. Inc., 65 Hayden Avenue, Lexington, MA, 02421, USA., Pandya BA; Cubist Pharmaceuticals, a wholly-owned subsidiary of Merck & Co. Inc., 65 Hayden Avenue, Lexington, MA, 02421, USA., Hwang YS; Cubist Pharmaceuticals, a wholly-owned subsidiary of Merck & Co. Inc., 65 Hayden Avenue, Lexington, MA, 02421, USA., Rye PT; Agilent Technologies, Inc., 11 Audubon Road, Wakefield, MA, 01880, USA., Muldoon C; Alchemia Limited, 3 Hi-Tech Court, Eight Mile Plains, Brisbane Technology Park, Qld, 4113, Australia., Becker B; Alchemia Limited, 3 Hi-Tech Court, Eight Mile Plains, Brisbane Technology Park, Qld, 4113, Australia., Zuegg J; Alchemia Limited, 3 Hi-Tech Court, Eight Mile Plains, Brisbane Technology Park, Qld, 4113, Australia., Meutermans W; Alchemia Limited, 3 Hi-Tech Court, Eight Mile Plains, Brisbane Technology Park, Qld, 4113, Australia., Moy TI; Cubist Pharmaceuticals, a wholly-owned subsidiary of Merck & Co. Inc., 65 Hayden Avenue, Lexington, MA, 02421, USA.

Publikováno v: Chemical biology & drug design [Chem Biol Drug Des] 2016 Feb; Vol. 87 (2), pp. 190-9. Date of Electronic Publication: 2015 Oct 09.

Advances in label-free screening approaches for studying histone acetyltransferases.

Autor: Rye PT; Agilent Technologies, Inc., Life Sciences Group, Wakefield, Massachusetts 01880, USA. peter.rye@agilent.com, Frick LE, Ozbal CC, Lamarr WA

Publikováno v: Journal of biomolecular screening [J Biomol Screen] 2011 Dec; Vol. 16 (10), pp. 1186-95. Date of Electronic Publication: 2011 Sep 09.

A bifunctional platinum(II) antitumor agent that forms DNA adducts with affinity for the estrogen receptor.

Autor: Kim E; Department of Chemistry and Department of Biological Engineering, Massachusetts Institute of Technology, Cambridge, MA 02139, USA., Rye PT, Essigmann JM, Croy RG

Publikováno v: Journal of inorganic biochemistry [J Inorg Biochem] 2009 Feb; Vol. 103 (2), pp. 256-61. Date of Electronic Publication: 2008 Oct 26.