Regulatory CD4(+) T cells recognize MHC-II-restricted peptide epitopes of apolipoprotein B

Autor: Kimura, Takayuki, Kobiyama, Kouji, Winkels, Holger, Tse, Kevin, Miller, Jacqueline, Vassallo, Melanie, Wolf, Dennis, Ryden, Christian, Orecchioni, Marco, Dileepan, Thamotharampillai, Jenkins, Marc K., James, Eddie A., Kwok, William W., Hanna, David B., Kaplan, Robert C., Strickler, Howard D., Durkin, Helen G., Kassaye, Seble G., Karim, Roksana, Tien, Phyllis C., Landay, Alan L., Gange, Stephen J., Sidney, John, Sette, Alessandro, Biol.Sci., Ley, Klaus

BACKGROUND: CD4(+) T cells play an important role in atherosclerosis, but their antigen specificity is poorly understood. Immunization with apolipoprotein B (ApoB, core protein of low density lipoprotein) is known to be atheroprotective in animal mod

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::e0ce74bac8ea2dd5513a6cfaec143efa
https://europepmc.org/articles/PMC6160361/

Regulatory CD4+T Cells Recognize Major Histocompatibility Complex Class II Molecule–Restricted Peptide Epitopes of Apolipoprotein B

Autor: Kimura, Takayuki, Kobiyama, Kouji, Winkels, Holger, Tse, Kevin, Miller, Jacqueline, Vassallo, Melanie, Wolf, Dennis, Ryden, Christian, Orecchioni, Marco, Dileepan, Thamotharampillai, Jenkins, Marc K., James, Eddie A., Kwok, William W., Hanna, David B., Kaplan, Robert C., Strickler, Howard D., Durkin, Helen G., Kassaye, Seble G., Karim, Roksana, Tien, Phyllis C., Landay, Alan L., Gange, Stephen J., Sidney, John, Sette, Alessandro, Ley, Klaus

Publikováno v: Circulation (Ovid); September 2018, Vol. 138 Issue: 11 p1130-1143, 14p

Regulatory CD4 ⁺ T Cells Recognize Major Histocompatibility Complex Class II Molecule-Restricted Peptide Epitopes of Apolipoprotein B.

Autor: Kimura T; Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (T.K., K.K., H.W., K.T., J.M., M.V., D.W., C.R., M.O., K.L.)., Kobiyama K; Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (T.K., K.K., H.W., K.T., J.M., M.V., D.W., C.R., M.O., K.L.)., Winkels H; Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (T.K., K.K., H.W., K.T., J.M., M.V., D.W., C.R., M.O., K.L.)., Tse K; Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (T.K., K.K., H.W., K.T., J.M., M.V., D.W., C.R., M.O., K.L.)., Miller J; Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (T.K., K.K., H.W., K.T., J.M., M.V., D.W., C.R., M.O., K.L.)., Vassallo M; Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (T.K., K.K., H.W., K.T., J.M., M.V., D.W., C.R., M.O., K.L.)., Wolf D; Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (T.K., K.K., H.W., K.T., J.M., M.V., D.W., C.R., M.O., K.L.)., Ryden C; Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (T.K., K.K., H.W., K.T., J.M., M.V., D.W., C.R., M.O., K.L.)., Orecchioni M; Division of Inflammation Biology, La Jolla Institute for Allergy and Immunology, CA (T.K., K.K., H.W., K.T., J.M., M.V., D.W., C.R., M.O., K.L.)., Dileepan T; Department of Microbiology, University of Minnesota Medical School, Minneapolis (T.D., M.K.J.)., Jenkins MK; Department of Microbiology, University of Minnesota Medical School, Minneapolis (T.D., M.K.J.)., James EA; Tetramer Core Laboratory, Benaroya Research Institute at Virginia Mason, Seattle, WA (E.A.J., W.W.K.)., Kwok WW; Tetramer Core Laboratory, Benaroya Research Institute at Virginia Mason, Seattle, WA (E.A.J., W.W.K.)., Hanna DB; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (D.B.H., R.C.K., H.D.S.)., Kaplan RC; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (D.B.H., R.C.K., H.D.S.)., Strickler HD; Department of Epidemiology and Population Health, Albert Einstein College of Medicine, Bronx, NY (D.B.H., R.C.K., H.D.S.)., Durkin HG; Department of Pathology, SUNY Downstate Medical Center, Brooklyn, NY (H.G.D.)., Kassaye SG; Department of Medicine, Georgetown University, Washington, DC (S.G.K.)., Karim R; Department of Preventive Medicine, Keck School of Medicine, University of Southern California, Los Angeles (R.K.)., Tien PC; Department of Medicine, University of California, San Francisco (P.C.T.)., Landay AL; Department of Microbial Pathogens and Immunity, Rush University Medical Center, Chicago, IL (A.L.L.)., Gange SJ; Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health, Baltimore, MD (S.J.G.)., Sidney J; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, CA (J.S., A.S.)., Sette A; Division of Vaccine Discovery, La Jolla Institute for Allergy and Immunology, CA (J.S., A.S.)., Ley K; Department of Bioengineering, University of California, San Diego, La Jolla (K.L.).

Publikováno v: Circulation [Circulation] 2018 Sep 11; Vol. 138 (11), pp. 1130-1143.