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Akademický článek

Overexpression of Fatty Acid Synthase Upregulates Glutamine-Fructose-6-Phosphate Transaminase 1 and O-Linked N-Acetylglucosamine Transferase to Increase O-GlcNAc Protein Glycosylation and Promote Colorectal Cancer Growth.

Autor: Drury J; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY 40536, USA., Geisen ME; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY 40536, USA., Tessmann JW; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY 40536, USA., Rychahou PG; Department of Surgery, University of Kentucky, Lexington, KY 40536, USA.; Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA., Kelson CO; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY 40536, USA., He D; Markey Cancer Center Biostatistics and Bioinformatics Shared Resource Facility, University of Kentucky, Lexington, KY 40536, USA., Wang C; Markey Cancer Center Biostatistics and Bioinformatics Shared Resource Facility, University of Kentucky, Lexington, KY 40536, USA., Evers BM; Department of Surgery, University of Kentucky, Lexington, KY 40536, USA.; Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA., Zaytseva YY; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY 40536, USA.; Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA.

Publikováno v: International journal of molecular sciences [Int J Mol Sci] 2024 Apr 30; Vol. 25 (9). Date of Electronic Publication: 2024 Apr 30.

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Akademický článek

Upregulation of CD36, a Fatty Acid Translocase, Promotes Colorectal Cancer Metastasis by Increasing MMP28 and Decreasing E-Cadherin Expression.

Autor: Drury J; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY 40536, USA., Rychahou PG; Department of Surgery and Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA., Kelson CO; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY 40536, USA., Geisen ME; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY 40536, USA., Wu Y; Biostatistics and Bioinformatics Shared Resource Facility, Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA., He D; Biostatistics and Bioinformatics Shared Resource Facility, Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA., Wang C; Biostatistics and Bioinformatics Shared Resource Facility, Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA., Lee EY; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, KY 40536, USA., Evers BM; Department of Surgery and Markey Cancer Center, University of Kentucky, Lexington, KY 40536, USA., Zaytseva YY; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY 40536, USA.

Publikováno v: Cancers [Cancers (Basel)] 2022 Jan 05; Vol. 14 (1). Date of Electronic Publication: 2022 Jan 05.

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Akademický článek

Inhibition of Fatty Acid Synthase Upregulates Expression of CD36 to Sustain Proliferation of Colorectal Cancer Cells.

Autor: Drury J; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, United States., Rychahou PG; Markey Cancer Center, University of Kentucky, Lexington, KY, United States.; Department of Surgery, University of Kentucky, Lexington, KY, United States., He D; Markey Cancer Center, University of Kentucky, Lexington, KY, United States., Jafari N; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, United States., Wang C; Markey Cancer Center, University of Kentucky, Lexington, KY, United States., Lee EY; Department of Pathology and Laboratory Medicine, University of Kentucky, Lexington, KY, United States., Weiss HL; Markey Cancer Center, University of Kentucky, Lexington, KY, United States., Evers BM; Markey Cancer Center, University of Kentucky, Lexington, KY, United States.; Department of Surgery, University of Kentucky, Lexington, KY, United States., Zaytseva YY; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, KY, United States.; Markey Cancer Center, University of Kentucky, Lexington, KY, United States.

Publikováno v: Frontiers in oncology [Front Oncol] 2020 Jul 31; Vol. 10, pp. 1185. Date of Electronic Publication: 2020 Jul 31 (Print Publication: 2020).

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Akademický článek

Novel chemotherapeutic agent, FND-4b, activates AMPK and inhibits colorectal cancer cell proliferation.

Autor: Sinner HF; Department of Surgery, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America., Johnson J; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America., Rychahou PG; Department of Surgery, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America., Watt DS; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America.; Center for Molecular Medicine, Organic Synthesis Core, University of Kentucky, Lexington, Kentucky, United States of America., Zaytseva YY; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.; Department of Toxicology and Cancer Biology, University of Kentucky, Lexington, Kentucky, United States of America., Liu C; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.; Department of Molecular and Cellular Biochemistry, University of Kentucky, Lexington, Kentucky, United States of America., Evers BM; Department of Surgery, University of Kentucky, Lexington, Kentucky, United States of America.; Markey Cancer Center, University of Kentucky, Lexington, Kentucky, United States of America.

Publikováno v: PloS one [PLoS One] 2019 Oct 24; Vol. 14 (10), pp. e0224253. Date of Electronic Publication: 2019 Oct 24 (Print Publication: 2019).

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Akademický článek

Membrane associated collagen XIII promotes cancer metastasis and enhances anoikis resistance.

Autor: Zhang H; Department of Laboratory Medicine, The First Hospital of Jilin University, Changchun, 130021, Jilin Province, China.; UK Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA., Fredericks T; Division of Gynecologic Oncology, Department of Obstetrics and Gynecology, University of Kentucky, Lexington, KY, 40504, USA., Xiong G; UK Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA., Qi Y; UK Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA., Rychahou PG; Department of Surgery, College of Medicine, University of Kentucky, Lexington, KY, 40504, USA., Li JD; Center for Medical Genetics, School of Life Sciences, Central South University, Changsha, 410078, Hunan Province, China., Pihlajaniemi T; Center for Cell-Matrix Research and Biocenter Oulu, Faculty of Biochemistry and Molecular Medicine, University of Oulu, 90014, Oulu, Finland., Xu W; Department of Laboratory Medicine, The First Hospital of Jilin University, Changchun, 130021, Jilin Province, China. xu_w@jlu.edu.cn., Xu R; UK Markey Cancer Center, University of Kentucky, Lexington, KY, 40536, USA. ren.xu2010@uky.edu.; Department of Pharmacology and Nutritional Sciences, University of Kentucky, Lexington, KY, 40536, USA. ren.xu2010@uky.edu.

Publikováno v: Breast cancer research : BCR [Breast Cancer Res] 2018 Oct 01; Vol. 20 (1), pp. 116. Date of Electronic Publication: 2018 Oct 01.

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