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pro vyhledávání: '"Ryan von Kleeck"'
Publikováno v:
Vascular Biology, Vol 4, Iss 1, Pp 1-10 (2022)
Hutchinson–Guilford Progeria syndrome (HGPS) is a rare genetic disease of premature aging and early death due to cardiovascular disease. The arteries of HGPS children and mice are pathologically stiff, and HGPS mice also display reduced arterial co
Externí odkaz:
https://doaj.org/article/d90451d8fe444425a33c7d098d6d959d
Autor:
Ryan von Kleeck, Paola Castagnino, Emilia Roberts, Shefali Talwar, Giovanni Ferrari, Richard K. Assoian
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-11 (2021)
Abstract Children with Hutchinson–Gilford Progeria Syndrome (HGPS) suffer from multiple cardiovascular pathologies due to the expression of progerin, a mutant form of the nuclear envelope protein Lamin A. Progerin expression has a dramatic effect o
Externí odkaz:
https://doaj.org/article/65657194454f4770992d55005dc6e736