Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Ryan Z. Friedman"'
Autor:
Tomas Lagunas, Stephen P. Plassmeyer, Anthony D. Fischer, Ryan Z. Friedman, Michael A. Rieger, Din Selmanovic, Simona Sarafinovska, Yvette K. Sol, Michael J. Kasper, Stuart B. Fass, Alessandra F. Aguilar Lucero, Joon-Yong An, Stephan J. Sanders, Barak A. Cohen, Joseph D. Dougherty
Publikováno v:
Communications Biology, Vol 6, Iss 1, Pp 1-14 (2023)
Abstract The function of regulatory elements is highly dependent on the cellular context, and thus for understanding the function of elements associated with psychiatric diseases these would ideally be studied in neurons in a living brain. Massively
Externí odkaz:
https://doaj.org/article/1be3cfd23894463dbf386a6bfd6edefd
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-14 (2020)
Abstract Background Transposable elements (TEs) make up half of mammalian genomes and shape genome regulation by harboring binding sites for regulatory factors. These include binding sites for architectural proteins, such as CTCF, RAD21, and SMC3, th
Externí odkaz:
https://doaj.org/article/dc11410e8de44842bee27f41e0a6c9b3
Autor:
Ryan Z. Friedman, Stacey R. Gish, Holly Brown, Lindsey Brier, Nicole Howard, Tamara L. Doering, Michael R. Brent
Publikováno v:
G3: Genes, Genomes, Genetics, Vol 8, Iss 3, Pp 815-822 (2018)
Received wisdom in the field of fungal biology holds that the process of editing a genome by transformation and homologous recombination is inherently mutagenic. However, that belief is based on circumstantial evidence. We provide the first direct me
Externí odkaz:
https://doaj.org/article/7d068d646ee04403ba4cbfca5f838b36
Autor:
Mayank N. K. Choudhary, Ryan Z. Friedman, Julia T. Wang, Hyo Sik Jang, Xiaoyu Zhuo, Ting Wang
Publikováno v:
Genome Biology, Vol 21, Iss 1, Pp 1-2 (2020)
Following publication of the original paper [1], an error was reported in the processing of Fig. 2. The correct Fig. 2 is supplied below and the original article [1] has been corrected. The publishers apologize for the error.
Externí odkaz:
https://doaj.org/article/78850894676443dfa07e18b7f22ae685
Autor:
Ryan Z Friedman, David M Granas, Connie A Myers, Joseph C Corbo, Barak A Cohen, Michael A White
Publikováno v:
eLife, Vol 10 (2021)
Enhancers and silencers often depend on the same transcription factors (TFs) and are conflated in genomic assays of TF binding or chromatin state. To identify sequence features that distinguish enhancers and silencers, we assayed massively parallel r
Externí odkaz:
https://doaj.org/article/84316855e8ba44709990ec78c1d8425e
Autor:
James L. Shepherdson, Ryan Z. Friedman, Yiqiao Zheng, Chi Sun, Inez Y. Oh, David M. Granas, Barak A. Cohen, Shiming Chen, Michael A. White
Publikováno v:
bioRxiv
Dozens of variants in the photoreceptor-specific transcription factor (TF) CRX are linked with different human blinding diseases that vary in their severity and age of onset. How different variants in a single TF cause a range of pathological phenoty
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f849484d39c188dd4caee3b346c53c3
https://europepmc.org/articles/PMC10245955/
https://europepmc.org/articles/PMC10245955/
Autor:
Kaiser J. Loell, Ryan Z. Friedman, Connie A. Myers, Joseph C. Corbo, Barak A. Cohen, Michael A. White
The effects of transcription factor binding sites (TFBSs) on the activity of acis-regulatory element (CRE) depend on the local sequence context. In rod photoreceptors, binding sites for the transcription factor (TF) Cone-rod homeobox (CRX) occur in b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fabbd7606672049f104a338a0eef8077
https://doi.org/10.1101/2023.03.05.531194
https://doi.org/10.1101/2023.03.05.531194
Autor:
Connie A. Myers, Michael A. White, Barak A. Cohen, David M Granas, Ryan Z. Friedman, Joseph C. Corbo
Publikováno v:
eLife, Vol 10 (2021)
eLife
eLife
Enhancers and silencers often depend on the same transcription factors (TFs) and are conflated in genomic assays of TF binding or chromatin state. To identify sequence features that distinguish enhancers and silencers, we assayed massively parallel r
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a461684dda22472c8f76121683e2a551
https://elifesciences.org/articles/67403
https://elifesciences.org/articles/67403
Autor:
Tomas Lagunas, Stephen P. Plassmeyer, Anthony D. Fischer, Ryan Z. Friedman, Michael A. Rieger, Din Selmanovic, Simona Sarafinovska, Alessandra F. Aguilar Lucero, Joon-Yong An, Stephan J. Sanders, Barak A. Cohen, Joseph D. Dougherty
Human genetic studies have identified a large number of disease-associated de novo variants in presumptive regulatory regions of the genome that pose a challenge for interpretation of their effects: the impact of regulatory variants is highly depende
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b5db31e91a8bfe4e901e442c6d89dc0c
https://doi.org/10.1101/2021.05.17.444514
https://doi.org/10.1101/2021.05.17.444514
Author response: Information content differentiates enhancers from silencers in mouse photoreceptors
Autor:
David M Granas, Joseph C. Corbo, Barak A. Cohen, Michael A. White, Ryan Z. Friedman, Connie A. Myers
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::459891419f0fcb97bcfbabf53fb6995b
https://doi.org/10.7554/elife.67403.sa2
https://doi.org/10.7554/elife.67403.sa2