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pro vyhledávání: '"Ryan Yoast"'
A calcium/cAMP signaling loop at the ORAI1 mouth drives channel inactivation to shape NFAT induction
Autor:
Xuexin Zhang, Trayambak Pathak, Ryan Yoast, Scott Emrich, Ping Xin, Robert M. Nwokonko, Martin Johnson, Shilan Wu, Céline Delierneux, Maxime Gueguinou, Nadine Hempel, James W. Putney, Donald L. Gill, Mohamed Trebak
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
ORAI1 constitutes the store-operated Ca2+ release-activated Ca2+ (CRAC) channel, but how this channel is turned off through Ca2+-dependent inactivation (CDI) remained unclear. Here the authors identify a spatially-restricted Ca2+/cAMP signaling cross
Externí odkaz:
https://doaj.org/article/273145bab6b34b6fac4674fdd0ecc38c
Autor:
Bastihalli T, Diwakar, Ryan, Yoast, Shaneice, Nettleford, Fenghua, Qian, Tai-Jung, Lee, Svanjita, Berry, Ian, Huffnagle, Randall M, Rossi, Mohamed, Trebak, Robert F, Paulson, K Sandeep, Prabhu
Publikováno v:
FASEB journal : official publication of the Federation of American Societies for Experimental Biology. 33(11)
Prostaglandin D(2) and its cyclopentenone metabolites [cyclopentenone prostaglandins (CyPGs)], Δ(12)prostaglandin J(2) and 15-deoxy-Δ(12,14)-prostaglandin J(2), act through 2 GPCRs, d-type prostanoid 1 and the chemoattractant receptor homologous mo