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Autor:
Peter Stacey, Gopal P. Sapkota, Georgina Green, Hannah Lithgow, Marcel Muelbaier, Glenn A. Burley, Andrew B. Benowitz, Ian Edward David Smith, Xiao Qing Lewell, Ryan Whatling, Markus A. Queisser, Agnieszka Konopacka, Robert P. Law, Stephen Besley, John D. Harling, Sascha Röth
Publikováno v:
SLAS Discovery. 26:885-895
Targeted protein degradation is an emerging new strategy for the modulation of intracellular protein levels with applications in chemical biology and drug discovery. One approach to enable this strategy is to redirect the ubiquitin-proteasome system