Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ryan W. Pearce"'
Autor:
Anamika Gangwar, Sneha S. Deodhar, Suzanne Saldanha, Olle Melander, Fahim Abbasi, Ryan W. Pearce, Timothy S. Collier, Michael J. McPhaul, Jeremy D. Furtado, Frank M. Sacks, Nathaniel J. Merrill, Jason E. McDermott, John T. Melchior, Anand Rohatgi
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 21, p 15526 (2023)
High-density lipoproteins (HDLs) are promising targets for predicting and treating atherosclerotic cardiovascular disease (ASCVD), as they mediate removal of excess cholesterol from lipid-laden macrophages that accumulate in the vasculature. This fun
Externí odkaz:
https://doaj.org/article/d54832be9c494103b706d50334610c81
Publikováno v:
The Journal of Clinical Endocrinology & Metabolism. 108:42-51
Context The mechanisms leading to increased cardiovascular disease in patients with nonalcoholic fatty liver disease (NAFLD) and advanced liver fibrosis remain incompletely understood. Objective This study assessed HDL-bound proteins in patients with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c9c6eb452c8f2f6801be2ebaf06315b3
https://doi.org/10.1210/clinem/dgac565
https://doi.org/10.1210/clinem/dgac565
Publikováno v:
Analytical Biochemistry. 640:114430
This study describes LC-ESI-MS/MS method that covers the analysis of various cellular acyl-CoA in a single injection. The method is based on a quick extraction step eliminating LLE/SPE clean up. Method performance characteristics were determined afte
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1039a6707ab94e1113173fb6d7c2e9e6
https://doi.org/10.1016/j.ab.2021.114430
https://doi.org/10.1016/j.ab.2021.114430
Autor:
Kuldeep Makwana, Roman V. Kondratov, Volha Mezhnina, Ryan W. Pearce, Yana Sandlers, Allan Poe, Oghogho P Ebeigbe, Artem A. Astafev, Nikkhil Velingkaar
Publikováno v:
Aging Cell
Calorie restriction (CR), an age delaying diet, affects fat oxidation through poorly understood mechanisms. We investigated the effect of CR on fat metabolism gene expression and intermediate metabolites of fatty acid oxidation in the liver. We found
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3d6b231331f1c0c8c880b08d7127d3eb
http://europepmc.org/articles/PMC7681051
http://europepmc.org/articles/PMC7681051
Publikováno v:
The journal of applied laboratory medicine. 5(4)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a869df5a6ed6060edb19d9bff6435097
https://pubmed.ncbi.nlm.nih.gov/32603433
https://pubmed.ncbi.nlm.nih.gov/32603433
Autor:
Jaividhya Dasarathy, Srinivasan Dasarathy, Arthur J. McCullough, Yana Sandlers, Rohan R. Shah, Ryan W. Pearce
Publikováno v:
Journal of Clinical Medicine, Vol 9, Iss 2, p 314 (2020)
Journal of Clinical Medicine
Volume 9
Issue 2
Journal of Clinical Medicine
Volume 9
Issue 2
Nonalcoholic liver disease (NAFLD) is manifested with a wide spectrum of clinical symptoms and is closely associated with the metabolic syndrome, inflammation, and mitochondrial dysfunction. Although the mechanism of mitochondrial dysfunction in NAFL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0538146d3202943479bca45e66bc066
https://www.mdpi.com/2077-0383/9/2/314
https://www.mdpi.com/2077-0383/9/2/314
Publikováno v:
MethodsX, Vol 7, Iss, Pp 100572-(2020)
MethodsX
MethodsX
Graphical abstract
Recent advances in human induced pluripotent stem cell-derived cardiomyocytes (iPSCM) field offer a novel platform for modeling cardiac metabolism, heart diseases drug candidates screening and cardiac toxicity assessments. The
Recent advances in human induced pluripotent stem cell-derived cardiomyocytes (iPSCM) field offer a novel platform for modeling cardiac metabolism, heart diseases drug candidates screening and cardiac toxicity assessments. The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::65e47bbc64bab0617e3a5938c2b5db0a
http://www.sciencedirect.com/science/article/pii/S2215016119301487
http://www.sciencedirect.com/science/article/pii/S2215016119301487
Publikováno v:
Clinical biochemistry. 73
Aldosterone is produced by the adrenal gland and plays an important role in blood pressure regulation and electrolyte hemostasis. Clinically, measurement of urine aldosterone provides evidence for the diagnosis of hyper- and hypo-aldosteronism. Urine
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6ecd2c53fc9def88af1d6cfb531f7af4
https://pubmed.ncbi.nlm.nih.gov/31376364
https://pubmed.ncbi.nlm.nih.gov/31376364
Autor:
Rohan R. Shah, Ryan W. Pearce, Yana Sandlers, Gina A. DeLeonibus, Alisha House, Erica M. Fatica, Liraz Levi, Jillian V. Kodger
Publikováno v:
Metabolites
Volume 9
Issue 12
Volume 9
Issue 12
Barth syndrome (BTHS) is an X-linked recessive multisystem disorder caused by mutations in the TAZ gene (TAZ, G 4.5, OMIM 300394) that encodes for the acyltransferase tafazzin. This protein is highly expressed in the heart and plays a significant rol
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::82ba31c19e56f12022a5c259f5cf0a88
https://doi.org/10.3390/metabo9120306
https://doi.org/10.3390/metabo9120306