Výsledky vyhledávání - "Ryan W. Mitchell"

Akademický článek

Delineating the role of alterations in lipid metabolism to the pathogenesis of inherited skeletal and cardiac muscle disorders

Autor: Harjot K. Saini-Chohan, Ryan W. Mitchell, Frédéric M. Vaz, Teresa Zelinski, Grant M. Hatch

Publikováno v: Journal of Lipid Research, Vol 53, Iss 1, Pp 4-27 (2012)

As the specific composition of lipids is essential for the maintenance of membrane integrity, enzyme function, ion channels, and membrane receptors, an alteration in lipid composition or metabolism may be one of the crucial changes occurring during s

Externí odkaz: https://doaj.org/article/790365bed8d7416f866dc092d1647520

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Akademický článek

Human trifunctional protein alpha links cardiolipin remodeling to beta-oxidation.

Autor: William A Taylor, Edgard M Mejia, Ryan W Mitchell, Patrick C Choy, Genevieve C Sparagna, Grant M Hatch

Publikováno v: PLoS ONE, Vol 7, Iss 11, p e48628 (2012)

Cardiolipin (CL) is a mitochondrial membrane phospholipid which plays a key role in apoptosis and supports mitochondrial respiratory chain complexes involved in the generation of ATP. In order to facilitate its role CL must be remodeled with appropri

Externí odkaz: https://doaj.org/article/3c5a673e544041d99c08e5a40439619b

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Fatty acid transport into the brain: Of fatty acid fables and lipid tails

Autor: Ryan W. Mitchell, Grant M. Hatch

Publikováno v: Prostaglandins, Leukotrienes and Essential Fatty Acids (PLEFA). 85:293-302

The blood-brain barrier formed by the brain capillary endothelial cells provides a protective barrier between the systemic blood and the extracellular environment of the central nervous system. Brain capillaries are a continuous layer of endothelial

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::147f6b929711dc2792cb02e3316b4105
https://doi.org/10.1016/j.plefa.2011.04.007

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On the mechanism of oleate transport across human brain microvessel endothelial cells

Autor: Donald W. Miller, Carmen L. Edmundson, Grant M. Hatch, Ryan W. Mitchell

Publikováno v: Journal of Neurochemistry. 110:1049-1057

The blood–brain barrier formed by the brain capillary endothelial cells provides a protective barrier between the systemic blood and the extracellular environment of the CNS. As most fatty acids in the brain enter from the blood, we examined the me

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3e52b6281931268253ffc8958108ab71
https://doi.org/10.1111/j.1471-4159.2009.06199.x

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Exogenous Arachidonic Acid Mediates Permeability of Human Brain Microvessel Endothelial Cells through Prostaglandin E 2 Activation of EP 3 and EP 4 Receptors

Autor: Hieu Nguyen, Harold M. Aukema, Ryan W. Mitchell, Donald W. Miller, Ngoc H. On, Siddhartha Dalvi, Grant M. Hatch

Publikováno v: The FASEB Journal. 29

The blood-brain barrier, formed by microvessel endothelial cells, is the restrictive barrier between the brain parenchyma and the circulating blood. Arachidonic acid (ARA; 5,8,11,14-cis-eicosatetraenoic acid) is a conditionally essential polyunsatura

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::19ad1e7196a6d2a23471be35cdcbb179
https://doi.org/10.1096/fasebj.29.1_supplement.715.32

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Exogenous arachidonic acid mediates permeability of human brain microvessel endothelial cells through prostaglandin E2 activation of EP3 and EP4 receptors

Autor: Donald W. Miller, Grant M. Hatch, Siddhartha Dalvi, Ngoc H. On, Hieu Nguyen, Harold M. Aukema, Ryan W. Mitchell

Publikováno v: Journal of neurochemistry. 135(5)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3e4ccceb137b2af5c6c327338b39e3c
https://pubmed.ncbi.nlm.nih.gov/26383055

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Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells

Autor: Ryan W, Mitchell, Ngoc H, On, Marc R, Del Bigio, Donald W, Miller, Grant M, Hatch

Publikováno v: Journal of neurochemistry. 117(4)

The blood-brain barrier (BBB), formed by the brain capillary endothelial cells, provides a protective barrier between the systemic blood and the extracellular environment of the CNS. Passage of fatty acids from the blood to the brain may occur either

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::6dcd1538b587daacf898e1f207756d69
https://pubmed.ncbi.nlm.nih.gov/21395585

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Mifepristone treatment results in differential regulation of glycerolipid biosynthesis in baby hamster kidney cells expressing a mifepristone-inducible ABCA1

Autor: Fred Y. Xu, Xiaohui Zha, David Mymin, Grant M. Hatch, Kristin Hauff, Patrick C. Choy, Thomas Dembinski, Ryan W. Mitchell

Publikováno v: Lipids. 46(9)

ATP binding cassette A1 (ABCA1) transports cholesterol, phospholipids and lipophilic molecules to and across cellular membranes. We examined if ABCA1 expression altered cellular de novo glycerolipid biosynthesis in growing Baby hamster kidney (BHK) c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31e592c4a842f4237b1b929f5b98196e
https://pubmed.ncbi.nlm.nih.gov/21710238

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Fatty acid transport protein expression in human brain and potential role in fatty acid transport across human brain microvessel endothelial cells

Autor: Donald W. Miller, Ryan W. Mitchell, Marc R. Del Bigio, Ngoc H. On, Grant M. Hatch

Publikováno v: Journal of Neurochemistry.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::c0f983066b0d985969aac5ae894d510a
https://doi.org/10.1111/j.1471-4159.2011.07245.x

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