Výsledky vyhledávání - "Ryan W. Heiniger"

Infection of human mucosal tissue by Pseudomonas aeruginosa requires sequential and mutually dependent virulence factors and a novel pilus-associated adhesin

Autor: Michael Koomey, Matthew C. Wolfgang, Raymond J. Pickles, Ryan W. Heiniger, Hanne C. Winther-Larsen

Publikováno v: Cellular Microbiology. 12:1158-1173

Tissue damage predisposes humans to life-threatening disseminating infection by the opportunistic pathogen Pseudomonas aeruginosa. Bacterial adherence to host tissue is a critical first step in this infection process. It is well established that P. a

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::7b3087b932f596b4b69553a2660fd9b5
https://doi.org/10.1111/j.1462-5822.2010.01461.x

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Crystal structure analysis reveals Pseudomonas PilY1 as an essential calcium-dependent regulator of bacterial surface motility

Autor: Kimberly A. Coggan, Matthew R. Redinbo, Matthew C. Wolfgang, Michael D. L. Johnson, Justin R. Sperlazza, Ryan W. Heiniger, Jillian Orans

Publikováno v: Proceedings of the National Academy of Sciences. 107:1065-1070

Several bacterial pathogens require the “twitching” motility produced by filamentous type IV pili (T4P) to establish and maintain human infections. Two cytoplasmic ATPases function as an oscillatory motor that powers twitching motility via cycles

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::06008be7f0928f1e526a201e4d43c793
https://doi.org/10.1073/pnas.0911616107

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Genetic and Functional Analyses of PptA, a Phospho-Form Transferase Targeting Type IV Pili in Neisseria gonorrhoeae

Autor: Hanne C. Winther-Larsen, Michael Koomey, Cecilia L. Næssan, Ryan W. Heiniger, Åsmund K. Røhr, Wolfgang Egge-Jacobsen, Finn Erik Aas, Matthew C. Wolfgang

Publikováno v: Journal of Bacteriology. 190:387-400

The PilE pilin subunit protein of Neisseria gonorrhoeae undergoes unique covalent modifications with phosphoethanolamine (PE) and phosphocholine (PC). The p ilin p hospho-form t ransferase A (PptA) protein, required for these modifications, shows seq

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ffa5b98a48bab60ccbc1b9bee91637ec
https://doi.org/10.1128/jb.00765-07

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Sequence analysis and functional characterization of the dialkylglycine decarboxylase gene DGD1 from Mycosphaerella graminicola

Autor: Jeffrey R. Shuster, Ryan W. Heiniger, Todd M. Dezwaan, Amy Skalchunes, Matthew M. Tanzer, Lisbeth Hamer, Kiichi Adachi, Keith A. Peoples, Grant H. Nelson

Publikováno v: Current Genetics. 43:358-363

Dialkylglycine decarboxylase is a pyridoxal phosphate-dependent enzyme in the aminotransferases class III group of enzymes. The enzyme is unique in terms of catalyzing both decarboxylation and transamination. Although the enzymatic activity is presen

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c0ec75b539e4382cfe1409855b4e1043
https://doi.org/10.1007/s00294-003-0402-7

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Infection of human mucosal tissue by Pseudomonas aeruginosa requires sequential and mutually dependent virulence factors and a novel pilus-associated adhesin

Autor: Ryan W, Heiniger, Hanne C, Winther-Larsen, Raymond J, Pickles, Michael, Koomey, Matthew C, Wolfgang

Publikováno v: Cellular microbiology. 12(8)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::48b56554c5587335fed0809868ae5538
https://pubmed.ncbi.nlm.nih.gov/20331639

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Global nutritional profiling for mutant and chemical mode-of-action analysis in filamentous fungi

Autor: Matthew M. Tanzer, Ryan W. Heiniger, Marie Coffin, Blaise A. Darveaux, Amy Skalchunes, Jeffrey R. Shuster, Herbert N. Arst

Publikováno v: Functionalintegrative genomics. 3(4)

We describe a method for gene function discovery and chemical mode-of-action analysis via nutrient utilization using a high throughput Nutritional Profiling platform suitable for filamentous microorganisms. We have optimized the growth conditions for

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4584836965ed1a2c4002e0eca53a4761
https://pubmed.ncbi.nlm.nih.gov/12898394

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