Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ryan W Feathers"'
Autor:
Nadine Norton, Pooja P Advani, Daniel J Serie, Xochiquetzal J Geiger, Brian M Necela, Bianca C Axenfeld, Jennifer M Kachergus, Ryan W Feathers, Jennifer M Carr, Julia E Crook, Alvaro Moreno-Aspitia, Panos Z Anastasiadis, Edith A Perez, E Aubrey Thompson
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153411 (2016)
Invasive lobular carcinoma (ILC) comprises approximately ~10-20% of breast cancers. In general, multifocal/multicentric (MF/MC) breast cancer has been associated with an increased rate of regional lymph node metastases. Tumor heterogeneity between fo
Externí odkaz:
https://doaj.org/article/9f82f46e2f784e179860013a8cb491d0
Autor:
Wan-Hsin Lin, Ryan W. Feathers, Lisa M. Cooper, Laura J. Lewis-Tuffin, Jiaxiang Chen, Jann N. Sarkaria, Panos Z. Anastasiadis
Publikováno v:
JCI Insight, Vol 8, Iss 13 (2023)
Glioblastomas (GBM) are aggressive tumors that lack effective treatments. Here, we show that the Rho family guanine nucleotide exchange factor Syx promotes GBM cell growth both in vitro and in orthotopic xenografts derived from patients with GBM. Gro
Externí odkaz:
https://doaj.org/article/88293167408845f6a8a970ef58fbb1c5
Autor:
Louis Y El Khoury, Wan Hsin Lin, James B Smadbeck, Michael T Barrett, Dorsay Sadeghian, Alexa F McCune, Giannoula Karagouga, John C Cheville, Faye R Harris, Lindsey M Kinsella, Ryan W Feathers, Janet L Schafer Klein, Marina RS Walther-Antonio, Sarah H Johnson, Alan R Penheiter, Giuseppe Cucinella, Gabriella Schivardi, Aditya Bhagwate, Mitesh J Borad, Aaron S Mansfield, Stephen J Murphy, Andrea Mariani, George Vasmatzis, Panos Z Anastasiadis, Saravut J Weroha, Alyssa M Larish
Publikováno v:
Epigenomics. 15:283-292
This work examines differences in chromatin accessibility, methylation, and response to DNA hypomethylating agents between mismatch repair-deficient and non-mismatch repair-deficient endometrial cancer. Next-generation sequencing of a stage 1B, grade
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::72a86d0d7b8765a8ddb7064dca4c3bb2
https://doi.org/10.2217/epi-2023-0026
https://doi.org/10.2217/epi-2023-0026
Autor:
Jann N. Sarkaria, William F. Elmquist, Nathalie Y.R. Agar, Panos Z. Anastasiadis, Ian F. Parney, Aaron J. Johnson, Gaspar J. Kitange, Jeanette E. Eckel-Passow, Paul A Decker, Shulan Tian, James Watters, Laurent Debussche, Cedric Barriere, Fang Jin, Karen E. Parrish, Ann C. Mladek, Isabelle Meaux, Rachael A. Vaubel, Ryan W. Feathers, Shuangling Zhang, David Calligaris, Daniel J. Ma, Minjee Kim
Controversy exists surrounding whether heterogeneous disruption of the blood–brain barrier (BBB), as seen in glioblastoma (GBM), leads to adequate drug delivery sufficient for efficacy in GBM. This question is especially important when using potent
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1456b2133a588e38554e1ad333e22fed
https://doi.org/10.1158/1535-7163.c.6537957.v1
https://doi.org/10.1158/1535-7163.c.6537957.v1
Autor:
Wan-Hsin Lin, Ryan W. Feathers, Lisa M. Cooper, Laura J. Lewis-Tuffin, Jann N. Sarkaria, Panos Z. Anastasiadis
Glioblastomas (GBM) are aggressive tumors that lack effective treatments. Here, we show that the Rho family guanine nucleotide exchange factor Syx promotes GBM cell growth both in vitro and in orthotopic GBM patient-derived xenografts. Growth defects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dfb8e567738f7515eba64b7436cbed53
https://doi.org/10.1101/2021.12.03.469255
https://doi.org/10.1101/2021.12.03.469255
Autor:
George Vasmatzis, J Weroha, Andrea Mariani, Ryan W. Feathers, W-H Lin, Leila A. Jones, Alexa McCune, Stephen J. Murphy, J Lynch, Alyssa Larish, Aaron S. Mansfield, Panos Z. Anastasiadis, Matthew S. Block, Faye R. Harris, Giannoula Karagouga, A Kumar, S Sotiriou, James B. Smadbeck, John C. Cheville
Publikováno v:
E-Posters.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::039d02ceeb1743d170c4c2a6e3743437
https://doi.org/10.1136/ijgc-2021-igcs.175
https://doi.org/10.1136/ijgc-2021-igcs.175
Autor:
Stephen J. Murphy, Minetta C. Liu, Faye R. Harris, Sarah H. Johnson, George Vasmatzis, Farhad Kosari, Ryan W. Feathers, Mitesh J. Borad, James B. Smadbeck, Sowjanya Reganti, Janet L. Schaefer Klein, Lin Yang, E. Aubrey Thompson, John Cheville, Panos Z. Anastasiadis
Publikováno v:
Mayo Clinic proceedings
Objective To select optimal therapies based on the detection of actionable genomic alterations in tumor samples is a major challenge in precision medicine. Methods We describe an effective process (opened December 1, 2017) that combines comprehensive
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::75ea1c014cc37ea75706a793420b18bd
http://europepmc.org/articles/PMC7251931
http://europepmc.org/articles/PMC7251931
Autor:
Ariana Mostafa, Alvaro G. Hernandez, C. L. Wright, Jenny Drnevich, Anurup Ganguli, Jacob Berger, Vahid Faramarzi, Andrew M. Smith, Rashid Bashir, Phuong Le, George Vasmatzis, Olaoluwa O. Adeniba, Panos Z. Anastasiadis, Yongdeok Kim, Wan-Hsin Lin, Ryan W. Feathers, C. Saavedra, Karla P. Ramos-Cruz, Farhad Kosari, G. J. Pagan Diaz
Publikováno v:
Science Advances
Tiny silicon microchip–based high-throughput hanging drop arrays allow drug screening and geometric control.
Existing three-dimensional (3D) culture techniques are limited by trade-offs between throughput, capacity for high-resolution imaging
Existing three-dimensional (3D) culture techniques are limited by trade-offs between throughput, capacity for high-resolution imaging
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5eeac17eba6b6ec94624b6c5d3049349
https://doi.org/10.1126/sciadv.abc1323
https://doi.org/10.1126/sciadv.abc1323
Autor:
Andrea Mariani, Janet L. Schaefer Klein, Jamie Lynch, Aaron S. Mansfield, S. John Weroha, Leila A. Jones, Michael T. Barrett, James B. Smadbeck, Alyssa Larish, Panos Z. Anastasiadis, George Vasmatzis, Mitesh J. Borad, Stephen J. Murphy, Faye R. Harris, Dorsay Sadeghian, Wan-Hsin Lin, Maureen A. Lemens, Angela Emanuel, Ryan W. Feathers
Publikováno v:
Gynecologic Oncology. 162:S114-S115
Objectives: Up-regulation of ERBB pathways represent targetable alterations in many high grade endometrial cancers (EC); ERBB3 amplifications in particular may contribute to ineffective pathway targeting due to persistent co-activation of other ERBB
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1c3f0fc3c5852216c0c0f975a8369c5e
https://doi.org/10.1016/s0090-8258(21)00860-x
https://doi.org/10.1016/s0090-8258(21)00860-x
Autor:
Aziza Nassar, Idris Tolgay Ocal, Sotiris Sotiriou, Paul A. Decker, Sejal Subhash Shah, Antonis Kourtidis, Panos Z. Anastasiadis, Mary T. Haddad, Ryan W. Feathers, Lindy J. Pence
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 1275, p 1275 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 3
International Journal of Molecular Sciences
Volume 22
Issue 3
Background: Inflammatory breast cancer is a highly aggressive form of breast cancer that robustly forms clusters of tumor emboli in dermal lymphatics and readily metastasizes. Inflammatory breast cancers express high levels of E-cadherin, the major p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8c062f6814f5a9b5fb0f35a415ae3cc7
https://doi.org/10.21203/rs.3.rs-57687/v1
https://doi.org/10.21203/rs.3.rs-57687/v1