Zobrazeno 1 - 7
of 7
pro vyhledávání: '"Ryan T. Howard"'
Autor:
Huawei Chen, Corinne Reimer, Stephen E. Fawell, Keith Mikule, Michael Zinda, Edward W. Tate, Paul D. Lyne, Jonathan R. Dry, Deborah Lawson, Michelle L. Lamb, Jeffrey W. Johannes, David A. Scott, Dan Widzowski, Michele Mayo, Ryan T. Howard, Nancy Su, Jiaquan Wu, Farzin Gharahdaghi, Wenxian Wang, Xin Wang, Jingwen Zhang, Philip Petteruti, Tony Cheung, Shaun E. Grosskurth, Zebin Wang
Supplemental Fig S1- S6
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::20c14ee784e9ce30d950b54ed3d29144
https://doi.org/10.1158/0008-5472.22418555
https://doi.org/10.1158/0008-5472.22418555
Autor:
Huawei Chen, Corinne Reimer, Stephen E. Fawell, Keith Mikule, Michael Zinda, Edward W. Tate, Paul D. Lyne, Jonathan R. Dry, Deborah Lawson, Michelle L. Lamb, Jeffrey W. Johannes, David A. Scott, Dan Widzowski, Michele Mayo, Ryan T. Howard, Nancy Su, Jiaquan Wu, Farzin Gharahdaghi, Wenxian Wang, Xin Wang, Jingwen Zhang, Philip Petteruti, Tony Cheung, Shaun E. Grosskurth, Zebin Wang
PARP proteins represent a class of post-translational modification enzymes with diverse cellular functions. Targeting PARPs has proven to be efficacious clinically, but exploration of the therapeutic potential of PARP inhibition has been limited to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4e72f443eea55562ffa6cc913b43229d
https://doi.org/10.1158/0008-5472.c.6510161.v1
https://doi.org/10.1158/0008-5472.c.6510161.v1
Autor:
Huawei Chen, Corinne Reimer, Stephen E. Fawell, Keith Mikule, Michael Zinda, Edward W. Tate, Paul D. Lyne, Jonathan R. Dry, Deborah Lawson, Michelle L. Lamb, Jeffrey W. Johannes, David A. Scott, Dan Widzowski, Michele Mayo, Ryan T. Howard, Nancy Su, Jiaquan Wu, Farzin Gharahdaghi, Wenxian Wang, Xin Wang, Jingwen Zhang, Philip Petteruti, Tony Cheung, Shaun E. Grosskurth, Zebin Wang
Supplemental materials
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::25c90f8ab65849ea462ef14da7c54638
https://doi.org/10.1158/0008-5472.22418558.v1
https://doi.org/10.1158/0008-5472.22418558.v1
Autor:
Sebastian Dengler, Ryan T. Howard, Vasily Morozov, Christos Tsiamantas, Zhiwei Liu, Christopher Dobrzanski, Vojislava Pophristic, Sophie Brameyer, Céline Douat, Hiroaki Suga, Ivan Huc
A helical aromatic foldamer was identified that undergoes tRNA acylation by a flexizyme and ribosomal peptide initiation with yields sufficiently high to perform an mRNA display selection of macrocyclic foldamer-peptide hybrids. A hybrid macrocyle bi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::761abc8ad402295a08324d7487ed7cd7
https://doi.org/10.26434/chemrxiv-2022-5rlmv
https://doi.org/10.26434/chemrxiv-2022-5rlmv
Publikováno v:
Target Discovery and Validation
Autor:
Charlie N Saunders, Ryan T. Howard, Paul Hemsley, Javier A Molina Bermejo, James S. Scott, Edward W. Tate, Jeffrey W. Johannes, Philip Petteruti
Publikováno v:
ACS Chemical Biology
Inhibition of the poly(ADP-ribose) polymerase (PARP) family of enzymes has become an attractive therapeutic strategy in oncology and beyond; however, chemical tools to profile PARP engagement in live cells are lacking. Herein, we report the design an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a0ef1b13545b46aaf99d8dbe059fea1c
http://hdl.handle.net/10044/1/77571
http://hdl.handle.net/10044/1/77571
Autor:
Michele Mayo, Tony Cheung, Jiaquan Wu, Nancy Su, Xin Wang, Dan Widzowski, Jeffrey W. Johannes, Michelle Lamb, Keith Mikule, Corinne Reimer, Paul Lyne, Shaun E. Grosskurth, Ryan T. Howard, Stephen Fawell, Jingwen Zhang, Edward W. Tate, Philip Petteruti, Huawei Chen, Michael Zinda, Scott David, Deborah Lawson, Farzin Gharahdaghi, Wenxian Wang, Jonathan R. Dry, Zebin Wang
PARP proteins represent a class of post-translational modification enzymes with diverse cellular functions. Targeting PARPs has proven to be efficacious clinically, but exploration of the therapeutic potential of PARP inhibition has been limited to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c41fd9f1d0989c85eba69777dc61354
http://hdl.handle.net/10044/1/64761
http://hdl.handle.net/10044/1/64761