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pro vyhledávání: '"Ryan T Harrison"'
Autor:
Ryan T Harrison, Eric C Bielefeld
Publikováno v:
Noise and Health, Vol 21, Iss 98, Pp 35-40 (2019)
Introduction: There are several key differences between impulse and continuous noise: the nature of the noise itself, the cochlear and neuronal structures affected, the severity to which they damage the auditory system, and the period of time in whic
Externí odkaz:
https://doaj.org/article/de4f05f25706432099d61dca96b64097
Autor:
Ryan T. Harrison, Eric C. Bielefeld
Publikováno v:
Noise & Health
Noise and Health, Vol 21, Iss 98, Pp 35-40 (2019)
Noise and Health, Vol 21, Iss 98, Pp 35-40 (2019)
Introduction: There are several key differences between impulse and continuous noise: the nature of the noise itself, the cochlear and neuronal structures affected, the severity to which they damage the auditory system, and the period of time in whic
Publikováno v:
The Journal of the Acoustical Society of America. 146:3790-3799
One of the ongoing challenges for hearing researchers is successful protection of the ear from noise injury. For decades, the most effective methods have been based on modifying the acoustic properties of the noise, either by reducing noise output fr
Publikováno v:
Antioxidantsredox signaling. 36(16-18)
Significance: Acquired sensorineural hearing loss is a major public health problem worldwide. The leading causes of sensorineural hearing loss are noise, aging, and ototoxic medications, with the k...
Publikováno v:
Hearing Research. 370:16-21
Cisplatin is a potent chemotherapeutic compound for which ototoxicity is a significant side effect. Cisplatin has shown sensitivity to circadian time, in that cisplatin is most effective as an anti-tumor compound, and least nephrotoxic, when given in
Autor:
Eric C. Bielefeld, Ryan T. Harrison
Publikováno v:
Neuroscience Letters. 684:127-131
Noise-induced hearing loss affects a large number of adults and children worldwide, and continues to be a major public health problem. The cochlea is an organ that maintains delicate metabolic homeostasis and precise mechanical architecture. Disrupti
Publikováno v:
Anti-Cancer Drugs. 27:780-786
Ototoxicity continues to be a major dose-limiting side effect of cis-diamminedichloroplatinum(II) (cisplatin). With an ongoing need to develop pharmaceutical protection strategies for cisplatin's ototoxicity, there is also a need to develop stable in
Publikováno v:
Hearing Research. 387:107878
The development of a clinically-relevant rodent model of cisplatin-induced hearing loss presents the challenges of finding the cumulative dose, dosing schedule, and rodent strain to induce a consistent level of threshold shift with low mortality. Thi
Autor:
Pezhman Salehi, Partha Thirumala, Yingying Chen, Jianxin Bao, Ryan T. Harrison, Jessica L. Mulvany, Jihao Ren, Eric C. Bielefeld, Qingyin Zheng, Bing Hu, Debin Lei, Sarah A Neton, Ziyu Qiu, Ebenezer N. Yamoah, Maria C. Perez-Flores, Yan Yu
Publikováno v:
Journal of the Association for Research in Otolaryngology : JARO. 19(6)
Noise is the most common occupational and environmental hazard, and noise-induced hearing loss (NIHL) is the second most common form of sensorineural hearing deficit. Although therapeutics that target the free-radical pathway have shown promise, none
Publikováno v:
The Laryngoscope. 125:E78-E83
Objectives/Hypothesis Cochlear preconditioning with low doses of kanamycin or noise can reduce susceptibility to noise- and ototoxic drug-induced hearing loss. The current study was undertaken to investigate whether a preconditioning regimen of low-d