Zobrazeno 1 - 10
of 16
pro vyhledávání: '"Ryan T Doctolero"'
Autor:
John M Carethers, Bhavya Murali, Bing Yang, Ryan T Doctolero, Akihiro Tajima, Ranor Basa, E Julieta Smith, Monte Lee, Ryan Janke, Tina Ngo, Ruth Tejada, Ming Ji, Matthew Kinseth, Betty L Cabrera, Katsumi Miyai, Temitope O Keku, Christopher F Martin, Joseph A Galanko, Robert S Sandler, Kathleen L McGuire
Publikováno v:
PLoS ONE, Vol 9, Iss 6, p e100461 (2014)
African American patients with colorectal cancer show higher mortality than their Caucasian counterparts. Biology might play a partial role, and prior studies suggest a higher prevalence for microsatellite instability (MSI) among cancers from African
Externí odkaz:
https://doaj.org/article/0bc71c3a9aa0440d979f149ce5a4fe5a
Autor:
Robert S. Sandler, Kathleen L. McGuire, Betty L. Cabrera, Temitope O. Keku, Monte Lee, Ruth Tejada, Joseph A. Galanko, E. Julieta Smith, Katsumi Miyai, Bing Yang, John M. Carethers, Bhavya Murali, Ryan T. Doctolero, Ryan Janke, Tina Ngo, Akihiro Tajima, Christopher F. Martin, Ming Ji, Matthew A. Kinseth, Ranor C. B. Basa
Publikováno v:
PLoS ONE
PLoS ONE, Vol 9, Iss 6, p e100461 (2014)
PLoS ONE, Vol 9, Iss 6, p e100461 (2014)
African American patients with colorectal cancer show higher mortality than their Caucasian counterparts. Biology might play a partial role, and prior studies suggest a higher prevalence for microsatellite instability (MSI) among cancers from African
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c1f05028d0678b20e3a51ada957f63b7
http://europepmc.org/articles/PMC4067325
http://europepmc.org/articles/PMC4067325
Autor:
Noel Weidner, Sherry C. Huang, E. Julieta Smith, Jeffrey Lee, Akihiro Tajima, Ryan T. Doctolero, John M. Carethers, Stayce E. Beck
Publikováno v:
Cancer. 117(3)
BACKGROUND: Patients with hamartomatous polyposis syndromes have increased risk for colorectal cancer (CRC). Although progression of polyps to carcinoma is observed, pathogenic mechanisms remain unknown. The authors examined whether familial hamartom
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e9298f8f58fff9c44ed46b73f32bfce
https://pubmed.ncbi.nlm.nih.gov/20845481
https://pubmed.ncbi.nlm.nih.gov/20845481
Autor:
E. Julieta Smith, Katsumi Miyai, Pascal Gervaz, Robert S. Sandler, Temitope O. Keku, Barbara H. Jung, Ryan T. Doctolero, John M. Carethers, Julio C. Alonso
Publikováno v:
International Journal of Cancer, Vol. 118, No 10 (2006) pp. 2509-13
High-frequency microsatellite unstable (MSI-H) colon tumors develop as a consequence of mutations at repetitive sequences in target genes. TGFBR2 and ACVR2, encoding TGFb superfamily receptors, and the proapoptotic gene BAX are frequent targets for f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3191e247f0b499779eb26476d11f9d35
Autor:
Jessie A. Satia, John M. Carethers, Robert S. Sandler, Temitope O. Keku, Joseph A. Galanko, Ryan T. Doctolero, Akihiro Tajima, Christopher Martin
Publikováno v:
Cancer epidemiology, biomarkersprevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology. 14(2)
Objective: Microsatellite instability (MSI) is one form of genomic instability that occurs in 10% to 20% of sporadic colon tumors and almost all hereditary nonpolyposis colon cancers. However, little is known about how environmental factors (e.g., di
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b7f2c97b7b5a885a91af8a85f18ab4ea
https://pubmed.ncbi.nlm.nih.gov/15734969
https://pubmed.ncbi.nlm.nih.gov/15734969
Autor:
Kentaro Sugano, Michiko Iwamoto, Dennis J. Ahnen, Akihiro Tajima, Wilbur A. Franklin, Ryan T. Doctolero, Edward J. Hoffenberg, John M. Carethers
Publikováno v:
Pediatric research. 57(1)
In the two conditions juvenile polyps (JPs) and juvenile polyposis coli (JPC), colonic polyps may have overlapping histologic and phenotypic appearance, but JPC confers a significant risk for colon adenocarcinoma. Although not thought to contain aden
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7ddbc5191fada9fc54b83178a2ee9f71
https://pubmed.ncbi.nlm.nih.gov/15557110
https://pubmed.ncbi.nlm.nih.gov/15557110
Autor:
E. Julieta Smith, Lanchinh Nguyen, Katsumi Miyai, Cynthia Behling, Christian A. Arnold, Ryan T. Doctolero, Ajay Goel, John M. Carethers, C. Richard Boland, Betty L. Cabrera, Akihiro Tajima
Publikováno v:
Gastroenterology. 126(2)
5-Fluorouracil improves mortality in stage III colorectal cancer patients. In vitro studies suggest that microsatellite instability influences cell survival after 5-fluorouracil treatment. We investigated the survival influence of 5-fluorouracil in p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ef09fa494837f9d67d3ae1ad575ddeb1
https://pubmed.ncbi.nlm.nih.gov/15300610
https://pubmed.ncbi.nlm.nih.gov/15300610
Autor:
Temitope O. Keku, Akihiro Tajima, Barbara H. Jung, John M. Carethers, Robert S. Sandler, Ryan T. Doctolero, Alexie K. Nguyen
Background & Aims: Colorectal tumors manifesting high-frequency microsatellite instability (MSI-H) develop genetically as a consequence of mutations in genes harboring repetitive DNA sequences. The activin type 2 receptor ( ACVR2 ), possessing 2 poly
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::94317fddd165fd6cc1960e07899684b9
Publikováno v:
PLoS ONE. 9:e103699
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::de5c871045efd64ddc14a4294ddae5c8
https://doi.org/10.1371/journal.pone.0103699
https://doi.org/10.1371/journal.pone.0103699
Autor:
Carol J Solomon, John M. Carethers, Ryan T. Doctolero, Oscar S. Brann, Jayde Kurland, Stacye Beck, Sherry Huang
Publikováno v:
American Journal of Gastroenterology. 99:S106
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c20ab7bd45e83c0d723b226651e5e463
https://doi.org/10.14309/00000434-200410001-00323
https://doi.org/10.14309/00000434-200410001-00323