Zobrazeno 1 - 10
of 149
pro vyhledávání: '"Ryan T, Flynn"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-9 (2022)
Abstract The advent of energy-specific collimation in pencil beam scanning (PBS) proton therapy has led to an improved lateral dose conformity for a variety of treatment sites, resulting in better healthy tissue sparing. Arc PBS delivery has also bee
Externí odkaz:
https://doaj.org/article/f21fad8eaf84493aaf1722cf9937915a
Autor:
Cameron M. Cushing, Michael S. Petronek, Kellie L. Bodeker, Sandy Vollstedt, Heather A. Brown, Emyleigh Opat, Nancy J. Hollenbeck, Thomas Shanks, Daniel J. Berg, Brian J. Smith, Mark C. Smith, Varun Monga, Muhammad Furqan, Matthew A. Howard, Jeremy D. Greenlee, Kranti A. Mapuskar, Joel St-Aubin, Ryan T. Flynn, Joseph J. Cullen, Garry R. Buettner, Douglas R. Spitz, John M. Buatti, Bryan G. Allen, Vincent A. Magnotta
Publikováno v:
Redox Biology, Vol 38, Iss , Pp 101804- (2021)
Pharmacological ascorbate (P-AscH-) combined with standard of care (SOC) radiation and temozolomide is being evaluated in a phase 2 clinical trial (NCT02344355) in the treatment of glioblastoma (GBM). Previously published data demonstrated that param
Externí odkaz:
https://doaj.org/article/ab946eefd1804c1cbcca282d6397675a
Autor:
Kristin Plichta, MD, PhD, Nathan Camden, BS, Muhammed Furqan, MD, Taher Abu Hejleh, MBBS, Gerald H. Clamon, MD, Jun Zhang, MD, PhD, Ryan T. Flynn, PhD, Sudershan K. Bhatia, MD, PhD, Mark C. Smith, MD, John M. Buatti, MD, Bryan G. Allen, MD, PhD
Publikováno v:
Advances in Radiation Oncology, Vol 2, Iss 4, Pp 581-587 (2017)
Purpose: The adrenal glands are a common site of metastases because of their rich blood supply. Previously, adrenal metastases were treated with systemic chemotherapy or, more rarely, with surgical resection or palliative radiation therapy. Stereotac
Externí odkaz:
https://doaj.org/article/8f05818fdec649d4b47c3f26df6e093b
Autor:
Blake R. Smith, Jennifer D. Kos, Joseph M. Caster, Abigail E Besemer, Yusung Kim, Ryan T. Flynn, David Dunkerley, Bonnie S. Wagner, Sarah A. Strand
Publikováno v:
Journal of Applied Clinical Medical Physics
This work presents a comprehensive commissioning and workflow development process of a real‐time, ultrasound (US) image‐guided treatment planning system (TPS), a stepper and a US unit. To adequately benchmark the system, commissioning tasks were
Autor:
Theodore J. Geoghegan, Jen Yu, Kaustubh A. Patwardhan, Patrick M. Hill, Blake R. Smith, Nicholas P. Nelson, Alonso N. Gutierrez, Daniel E. Hyer, Suresh Rana, Wesley S. Culberson, Ryan T. Flynn
Publikováno v:
Med Phys
Purpose The aim of this work was to develop and experimentally validate a Dynamic Collimation Monte Carlo (DCMC) simulation package specifically designed for the simulation of collimators in pencil beam scanning proton therapy (PBS-PT). The DCMC pack
Autor:
Nicholas P Nelson, Wesley S Culberson, Daniel E Hyer, Theodore J Geoghegan, Kaustubh A Patwardhan, Blake R Smith, Ryan T Flynn, Jen Yu, Alonso N Gutiérrez, Patrick M Hill
Publikováno v:
Physics in Medicine & Biology. 68:055003
Objective. Pencil beam scanning (PBS) proton therapy target dose conformity can be improved with energy layer-specific collimation. One such collimator is the dynamic collimation system (DCS), which consists of four nickel trimmer blades that interce
Publikováno v:
Med Phys
PURPOSE: To present a system for the treatment of prostate cancer in a single-fraction regimen using (169)Yb-based rotating shield brachytherapy (RSBT) with a single-catheter robotic delivery system. The proposed system is innovative because it can d
Publikováno v:
Medical Physics. 47:5779-5790
Purpose This study aims to experimentally validate the Monte Carlo generated absorbed doses from the beta particles emitted by 90 Y and 177 Lu using radiochromic EBT3 film-based dosimetry. Methods Line sources of 90 Y and 177 Lu were inserted longitu
Autor:
Suresh Rana, Theodore J. Geoghegan, Patrick M. Hill, Ryan T. Flynn, Nicholas P. Nelson, Daniel E. Hyer
Publikováno v:
Med Phys
Purpose When designing a collimation system for pencil beam spot scanning proton therapy, a decision must be made whether or not to rotate, or focus, the collimator to match beamlet deflection as a function of off-axis distance. If the collimator is
Autor:
Karolyn M. Hopfensperger, Kaustubh Patwardhan, Quentin Adams, Yusung Kim, Joseph M. Caster, Xiaodong Wu, Bounnak Thammavong, Ryan T. Flynn, Weiyu Xu
Publikováno v:
Medical Physics. 47:2061-2071
Purpose To assess the capability of an intracavitary 169 Yb-based helical multishield rotating shield brachytherapy (RSBT) delivery system to treat cervical cancer. The proposed RSBT delivery system contains a pair of 1.25 mm thick platinum partial s