Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Ryan T, Behrens"'
Autor:
Brian J Snow, Nida K Keles, Michael W Grunst, Sanath Kumar Janaka, Ryan T Behrens, David T Evans
Publikováno v:
PLoS Pathogens, Vol 20, Iss 10, p e1012665 (2024)
Antibody-dependent cellular phagocytosis (ADCP) has been implicated in protection against HIV-1. However, methods for measuring ADCP currently rely on the phagocytosis of gp120- or gp41-coated beads that do not reflect physiologically relevant confor
Externí odkaz:
https://doaj.org/article/1b2bfa927d4c448784f223ba2a7c0b7c
Autor:
Ryan T. Behrens, Nathan M. Sherer
Publikováno v:
mBio, Vol 14, Iss 6 (2023)
ABSTRACTRecent advances in the study of virus-cell interactions have improved our understanding of how viruses that replicate their genomes in the nucleus (e.g., retroviruses, hepadnaviruses, herpesviruses, and a subset of RNA viruses) hijack cellula
Externí odkaz:
https://doaj.org/article/101f6769d7484183aef05a06e60afea7
Autor:
Ryan T. Behrens, Jyothi Krishnaswamy Rajashekar, James W. Bruce, Edward L. Evans, Amelia M. Hansen, Natalia Salazar-Quiroz, Lacy M. Simons, Paul Ahlquist, Judd F. Hultquist, Priti Kumar, Nathan M. Sherer
Publikováno v:
mBio, Vol 14, Iss 5 (2023)
ABSTRACT HIV-1 virion production is inefficient in cells derived from mice and other rodents reflecting cell-intrinsic defects to interactions between the HIV-1 auxiliary proteins Tat and Rev and host dependency factors CCNT1 (Cyclin T1) and XPO1 (ex
Externí odkaz:
https://doaj.org/article/e49508a9b94142c094747a11d2fbff48
Autor:
Shengjie Zhang, Fabao Liu, Peter Halfmann, Ryan T. Behrens, Peng Liu, Sean J. Mcilwain, Irene M. Ong, Kristine Donahue, Yidan Wang, Yoshihiro Kawaoka, Nathan Sherer, Wei Xu
Publikováno v:
Genes and Diseases, Vol 9, Iss 1, Pp 5-8 (2022)
Externí odkaz:
https://doaj.org/article/570223b2d1684ed89592252af6895afc
Autor:
Edward L. Evans, Ginger M. Pocock, Gabriel Einsdorf, Ryan T. Behrens, Ellen T. A. Dobson, Marcel Wiedenmann, Christian Birkhold, Paul Ahlquist, Kevin W. Eliceiri, Nathan M. Sherer
Publikováno v:
Viruses, Vol 14, Iss 5, p 903 (2022)
Single-cell imaging has emerged as a powerful means to study viral replication dynamics and identify sites of virus–host interactions. Multivariate aspects of viral replication cycles yield challenges inherent to handling large, complex imaging dat
Externí odkaz:
https://doaj.org/article/39386aafa62e4211a1d9f4e662eefe2e
Autor:
Ryan T. Behrens, Jyothi Krishnaswamy Rajashekar, James W. Bruce, Edward L. Evans, Amelia M. Hansen, Natalia Salazar-Quiroz, Lacy M. Simons, Paul Ahlquist, Judd F. Hultquist, Priti Kumar, Nathan M. Sherer
HIV-1 virion production is inefficient in cells derived from mice and other rodents reflecting cell-intrinsic defects to interactions between the HIV-1 auxiliary proteins Tat and Rev and host dependency factors CCNT1 (Cyclin T1) and XPO1 (Exportin-1,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05ac50ab593493585bb07a69abc7625a
https://doi.org/10.1101/2023.04.08.536105
https://doi.org/10.1101/2023.04.08.536105
Autor:
Christopher J, Little, William J, Haynes, Liupei, Huang, Cross M, Daffada, Bryce K, Wolfe, Elizabeth, Perrin, John A, Simpson, Jenna A, Kropp Schmidt, Hayly M, Hinkle, Logan T, Keding, Ryan T, Behrens, David T, Evans, Dixon B, Kaufman, James A, Thomson, Thaddeus G, Golos, Matthew E, Brown
Publikováno v:
Journal of Leukocyte Biology. 112:759-769
Nonhuman primates (NHPs) represent one of the most important models for preclinical studies of novel biomedical interventions. In contrast with small animal models, however, widespread utilization of NHPs is restricted by cost, logistics, and availab
Autor:
Yoshihiro Kawaoka, Peng Liu, Shengjie Zhang, Wei Xu, Yidan Wang, Kristine Donahue, Fabao Liu, Irene M. Ong, Peter Halfmann, Nathan M. Sherer, Sean J. McIlwain, Ryan T. Behrens
Publikováno v:
Genes & Diseases
Genes and Diseases, Vol 9, Iss 1, Pp 5-8 (2022)
Genes and Diseases, Vol 9, Iss 1, Pp 5-8 (2022)
Autor:
Shi Hua Xiang, Shuliang Chen, Wuxun Lu, Li Wu, Joshua Wiggins, Ryan T. Behrens, Shan-Lu Liu, Yong Xiong, Jingyou Yu, Nathan M. Sherer
Publikováno v:
Journal of virology. 93(7)
HIV-1 enters cells through binding between viral envelope glycoprotein (Env) and cellular receptors to initiate virus and cell fusion. HIV-1 Env precursor (gp160) is cleaved into two units noncovalently bound to form a trimer on virions, including a
Publikováno v:
Journal of Virology. 91
HIV-1's Rev protein forms a homo-oligomeric adaptor complex linking viral RNAs to the cellular CRM1/Ran-GTP nuclear export machinery through the activity of Rev's prototypical leucine-rich nuclear export signal (NES). In this study, we used a functio