Low cost and real-time surveillance of enteric infection and diarrhoeal disease using rapid diagnostic tests in Cox’s Bazar, Bangladesh

Autor: Samuel I. Watson, Mohammed Atique Ul Alam, Ryan T. T. Rego, Richard J. Lilford, Ashok Kumar Barman, Baharul Alam, A. S. G. Faruque, Md. Sirajul Islam

Publikováno v: Conflict and Health, Vol 18, Iss 1, Pp 1-12 (2024)

Abstract Background Real-time disease surveillance is an important component of infection control in at-risk populations. However, data on cases or from lab testing is often not available in many low-resource settings. Rapid diagnostic tests (RDT), i

Externí odkaz: https://doaj.org/article/56100aa1dfcd462e9e4b75c23c3780b5

The extensive m5C epitranscriptome of Thermococcus kodakarensis is generated by a suite of RNA methyltransferases that support thermophily

Autor: Kristin A. Fluke, Ryan T. Fuchs, Yueh-Lin Tsai, Victoria Talbott, Liam Elkins, Hallie P. Febvre, Nan Dai, Eric J. Wolf, Brett W. Burkhart, Jackson Schiltz, G. Brett Robb, Ivan R. Corrêa, Thomas J. Santangelo

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

Abstract RNAs are often modified to invoke new activities. While many modifications are limited in frequency, restricted to non-coding RNAs, or present only in select organisms, 5-methylcytidine (m5C) is abundant across diverse RNAs and fitness-relev

Externí odkaz: https://doaj.org/article/af268ebdcd824d6989e97d95df96dc37

Understanding mechanisms of generalization following locomotor adaptation

Autor: Cristina Rossi, Ryan T. Roemmich, Amy J. Bastian

Publikováno v: npj Science of Learning, Vol 9, Iss 1, Pp 1-16 (2024)

Abstract Our nervous system has the remarkable ability to adapt our gait to accommodate changes in our body or surroundings. However, our adapted walking patterns often generalize only partially (or not at all) between different contexts. Here, we so

Externí odkaz: https://doaj.org/article/e9ba23b70c5249f6ae849a3374f3f796

Cosmic kidney disease: an integrated pan-omic, physiological and morphological study into spaceflight-induced renal dysfunction

Autor: Keith Siew, Kevin A. Nestler, Charlotte Nelson, Viola D’Ambrosio, Chutong Zhong, Zhongwang Li, Alessandra Grillo, Elizabeth R. Wan, Vaksha Patel, Eliah Overbey, JangKeun Kim, Sanghee Yun, Michael B. Vaughan, Chris Cheshire, Laura Cubitt, Jessica Broni-Tabi, Maneera Yousef Al-Jaber, Valery Boyko, Cem Meydan, Peter Barker, Shehbeel Arif, Fatemeh Afsari, Noah Allen, Mohammed Al-Maadheed, Selin Altinok, Nourdine Bah, Samuel Border, Amanda L. Brown, Keith Burling, Margareth Cheng-Campbell, Lorianna M. Colón, Lovorka Degoricija, Nichola Figg, Rebecca Finch, Jonathan Foox, Pouya Faridi, Alison French, Samrawit Gebre, Peter Gordon, Nadia Houerbi, Hossein Valipour Kahrood, Frederico C. Kiffer, Aleksandra S. Klosinska, Angela Kubik, Han-Chung Lee, Yinghui Li, Nicholas Lucarelli, Anthony L. Marullo, Irina Matei, Colleen M. McCann, Sayat Mimar, Ahmed Naglah, Jérôme Nicod, Kevin M. O’Shaughnessy, Lorraine Christine De Oliveira, Leah Oswalt, Laura Ioana Patras, San-huei Lai Polo, María Rodríguez-Lopez, Candice Roufosse, Omid Sadeghi-Alavijeh, Rebekah Sanchez-Hodge, Anindya S. Paul, Ralf Bernd Schittenhelm, Annalise Schweickart, Ryan T. Scott, Terry Chin Choy Lim Kam Sian, Willian A. da Silveira, Hubert Slawinski, Daniel Snell, Julio Sosa, Amanda M. Saravia-Butler, Marshall Tabetah, Erwin Tanuwidjaya, Simon Walker-Samuel, Xiaoping Yang, Yasmin, Haijian Zhang, Jasminka Godovac-Zimmermann, Pinaki Sarder, Lauren M. Sanders, Sylvain V. Costes, Robert A. A. Campbell, Fathi Karouia, Vidya Mohamed-Alis, Samuel Rodriques, Steven Lynham, Joel Ricky Steele, Sergio Baranzini, Hossein Fazelinia, Zhongquan Dai, Akira Uruno, Dai Shiba, Masayuki Yamamoto, Eduardo A.C.Almeida, Elizabeth Blaber, Jonathan C. Schisler, Amelia J. Eisch, Masafumi Muratani, Sara R. Zwart, Scott M. Smith, Jonathan M. Galazka, Christopher E. Mason, Afshin Beheshti, Stephen B. Walsh

Publikováno v: Nature Communications, Vol 15, Iss 1, Pp 1-20 (2024)

Abstract Missions into Deep Space are planned this decade. Yet the health consequences of exposure to microgravity and galactic cosmic radiation (GCR) over years-long missions on indispensable visceral organs such as the kidney are largely unexplored

Externí odkaz: https://doaj.org/article/314b862fbe6c4c54a23cb008317e48c9

Potent broadly neutralizing antibodies mediate efficient antibody-dependent phagocytosis of HIV-infected cells.

Autor: Brian J Snow, Nida K Keles, Michael W Grunst, Sanath Kumar Janaka, Ryan T Behrens, David T Evans

Publikováno v: PLoS Pathogens, Vol 20, Iss 10, p e1012665 (2024)

Antibody-dependent cellular phagocytosis (ADCP) has been implicated in protection against HIV-1. However, methods for measuring ADCP currently rely on the phagocytosis of gp120- or gp41-coated beads that do not reflect physiologically relevant confor

Externí odkaz: https://doaj.org/article/1b2bfa927d4c448784f223ba2a7c0b7c