Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Ryan Swoyer"'
Autor:
Aimin Tang, Zhifeng Chen, Kara S. Cox, Hua-Poo Su, Cheryl Callahan, Arthur Fridman, Lan Zhang, Sangita B. Patel, Pedro J. Cejas, Ryan Swoyer, Sinoeun Touch, Michael P. Citron, Dhanasekaran Govindarajan, Bin Luo, Michael Eddins, John C. Reid, Stephen M. Soisson, Jennifer Galli, Dai Wang, Zhiyun Wen, Gwendolyn J. Heidecker, Danilo R. Casimiro, Daniel J. DiStefano, Kalpit A. Vora
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-13 (2019)
Respiratory syncytial virus (RSV) is a leading cause of infant hospitalization. Here, the authors isolate a human monoclonal antibody that binds to a highly conserved epitope on the RSV fusion protein, neutralizes RSV A and B subtypes equipotently an
Externí odkaz:
https://doaj.org/article/353ee58e3241465cbd5aae22b7984ad3
Autor:
Jessica A Flynn, Eberhard Durr, Ryan Swoyer, Pedro J Cejas, Melanie S Horton, Jennifer D Galli, Scott A Cosmi, Amy S Espeseth, Andrew J Bett, Lan Zhang
Publikováno v:
PLoS ONE, Vol 11, Iss 10, p e0164789 (2016)
Infection with Respiratory Syncytial Virus (RSV) causes both upper and lower respiratory tract disease in humans, leading to significant morbidity and mortality in both young children and older adults. Currently, there is no licensed vaccine availabl
Externí odkaz:
https://doaj.org/article/48f35b7eeaad4ea8b2956b94461371da
Autor:
Zhifeng Chen, Lan Zhang, Aimin Tang, Cheryl Callahan, Pavlo Pristatsky, Ryan Swoyer, Pedro Cejas, Debbie Nahas, Jennifer Galli, Scott Cosmi, Daniel DiStefano, Van M Hoang, Andrew Bett, Danilo Casimiro, Kalpit A Vora
Publikováno v:
PLoS ONE, Vol 11, Iss 6, p e0156798 (2016)
Respiratory syncytial virus (RSV) is a leading cause of lower respiratory tract infection in infants, the elderly and in immunosuppressed populations. The vast majority of neutralizing antibodies isolated from human subjects target the RSV fusion (F)
Externí odkaz:
https://doaj.org/article/73155741d0404b628aaa41985e4d1d0a
Autor:
Andrew J. Bett, Dai Wang, Zhiyun Wen, Andrew H. Latham, Lan Zhang, Kalpit A. Vora, Michael P. Citron, Jeffrey S. Smith, Marian E. Gindy, Christine A. Shaw, Joseph M. Antonello, Jessica A. Flynn, Ryan Swoyer, Cheryl Callahan, Giuseppe Ciaramella, Paloma Cejas, Daniel J. DiStefano, Kapil Bahl, Daniel C. Freed, Kara S. Cox, Gregory O’ Donnell, Amy S. Espeseth, Sinoeun Touch, Jennifer D. Galli, Daria J. Hazuda
Publikováno v:
NPJ Vaccines
npj Vaccines, Vol 5, Iss 1, Pp 1-14 (2020)
npj Vaccines, Vol 5, Iss 1, Pp 1-14 (2020)
The RSV Fusion (F) protein is a target for neutralizing antibody responses and is a focus for vaccine discovery; however, the process of RSV entry requires F to adopt a metastable prefusion form and transition to a more stable postfusion form, which
Autor:
Robert Hepler, Cook James C, Bob J. Lucas, Eberhard Durr, Amy S. Espeseth, James M. Wagner, Jennifer D. Galli, Debbie D. Nahas, Robin M. Kaufhold, Joseph G. Joyce, Ryan Swoyer, Jessica A. Flynn
Publikováno v:
Protein Science. 27:1923-1941
Chlamydial major outer membrane protein (MOMP) is the major protein constituent of the bacterial pathogen Chlamydia trachomatis. Chlamydia trachomatis Serovars D-K are the leading cause of genital tract infections which can lead to infertility or ect
Autor:
Aimin Tang, Jiang Zhu, Charles D. Morris, Zhiqiang An, Alan D.T. Barrett, Xi He, Leike Li, Ryan Swoyer, Daria J. Hazuda, Yaping Liu, Qinjian Zhao, Wenxin Luo, Daniel C. Freed, Lin Xia, Sha Ha, Ningshao Xia, Amy S. Espeseth, Fengsheng Li, Ningyan Zhang, Weixu Meng, Linling He, Wei Xiong, Dai Wang, Yu Zhou, Tong-Ming Fu, Xun Gui, Haotai Chen, I-Ming Wang, Robbie D. Schultz, Richard E. Rupp
Publikováno v:
Oncotarget
Human cytomegalovirus (HCMV) can cause life-threatening infection in immunosuppressed patients, and in utero infection that may lead to birth defects. No vaccine is currently available. HCMV infection in healthy subjects is generally asymptomatic, an
Autor:
Andrew J. Bett, Michael J. Eddins, Paloma Cejas, Gwen Heidecker, Kara S. Cox, Xi He, Stephen M. Soisson, Mike Citron, Cook James C, Zhiyun Wen, Kalpit A. Vora, Christopher Haines, Danilo R. Casimiro, Hua-Poo Su, Arthur Fridman, Aimin Tang, John C. Reid, Zhifeng Chen, Govindarajan Dhanasekeran, Dai Wang, Scott Cosmi, Jessica A. Flynn, Wade Blair, Bin Luo, Daniel J. DiStefano, Jennifer D. Galli, Sangita B. Patel, Lan Zhang, Ryan Swoyer, Cheryl Callahan, Debbie D. Nahas
Publikováno v:
Open Forum Infectious Diseases
Background Respiratory syncytial virus (RSV) infection is a major public health burden for infants and the elderly worldwide. Currently, there are no approved vaccines and only one moderately effective marketed antibody (Synagis®) for the prevention
Autor:
Jennifer Galli, Maya Salnikova, Michael Cai, John W. Balliet, Sandra Rios, Robert C. Davidson, Danilo R. Casimiro, Sita Awasthi, Harvey M. Friedman, Martha Brown, John M. Lubinski, Carolyn E. Shaw, Ryan Swoyer, Judith F. Smith, Susan Kingsley, Rose Kowalski, Janine T. Bryan, Daniel J. DiStefano, Victoria Copeland, Jessica A. Flynn
Publikováno v:
Journal of Virology. 88:2000-2010
A prophylactic vaccine for genital herpes disease remains an elusive goal. We report the results of two studies performed collaboratively in different laboratories that assessed immunogenicity and vaccine efficacy in herpes simplex virus 1 (HSV-1)-se
Autor:
Linda T. Ecto, Rohini Datta, Raksha Das, Michael P. Citron, Nonavinakere Seetharam Srilatha, Somnath Dutta, Jessica A. Flynn, Sannula Kesavardhana, Daniel J. DiStefano, Raghavan Varadarajan, Celia C. LaBranche, David C. Montefiori, Joseph G. Joyce, Ryan Swoyer
A major goal for HIV-1 vaccine development is an ability to elicit strong and durable broadly neutralizing antibody (bNAb) responses. The trimeric envelope glycoprotein (Env) spikes on HIV-1 are known to contain multiple epitopes that are susceptible
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::68ebc3a07861894730d0dfc775a71119
https://europepmc.org/articles/PMC5217686/
https://europepmc.org/articles/PMC5217686/
Autor:
John Lawson, Christine C. Roberts, Elizabeth A. Else, Yuhua Zhang, Janine T. Bryan, Ryan Swoyer, Inez Van Hyfte, Frank J. Taddeo
Publikováno v:
Journal of Clinical Microbiology. 49:1907-1912
Real-time type-specific multiplex human papillomavirus (HPV) PCR assays were developed to detect HPV DNA in samples collected for the efficacy determination of the quadrivalent HPV (type 6, 11, 16, and 18) L1 virus-like particle (VLP) vaccine (Gardas