Zobrazeno 1 - 10
of 147
pro vyhledávání: '"Ryan Sun"'
Autor:
Syeda Akila Ally, Jin Han, Ryan Sun, Robert E. Molokie, Victor R. Gordeuk, James P. Lash, Santosh L. Saraf
Publikováno v:
eJHaem, Vol 4, Iss 2, Pp 432-436 (2023)
Abstract Sickle cell anemia (SCA) negatively impacts the ability to achieve educational and occupational goals increasing vulnerability to socioeconomic challenges. In a cross‐sectional analysis of 332 SCA adults, we investigated whether the distre
Externí odkaz:
https://doaj.org/article/1822006a1519442495b251448f6a8d27
Autor:
Andrew P. Jallouk, Naishu Kui, Ryan Sun, Jason R. Westin, Raphael E. Steiner, Ranjit Nair, Loretta J. Nastoupil, Luis E. Fayad, Ajlan Al Zaki, Misha Hawkins, Sherry Adkins, Mansoor Noorani, Kaberi Das, Jared Henderson, Elizabeth J. Shpall, Partow Kebriaei, Jeremy Ramdial, Christopher R. Flowers, Sattva S. Neelapu, Sairah Ahmed, Paolo Strati
Publikováno v:
Haematologica, Vol 109, Iss 5 (2023)
Complications occurring after lymphodepleting chemotherapy (LDC) may delay chimeric antigen receptor (CAR) T-cell infusion. The effect of these delays on clinical outcomes is unclear. We performed a retrospective analysis of 240 patients with relapse
Externí odkaz:
https://doaj.org/article/b01259b6f4fa46b6872193b9823dd88d
Autor:
Michael Green, Jingwei Liu, Zheng Zhang, Fuliang Chu, Sattva S Neelapu, Laura Bover, Ryan Sun, Jingjing Cao, Haopeng Yang, Timothy J Davis, Shao-qing Kuang, Xiaoyun Cheng, Swathi Karri, Long T Vien, Francisco Vega, Richard Eric Davis
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 11, Iss 11 (2023)
Background Chimeric antigen receptor (CAR) T cells targeting CD19 mediate potent and durable effects in B-cell malignancies. However, antigen loss or downregulation is a frequent cause of resistance. Here, we report development of a novel CAR T-cell
Externí odkaz:
https://doaj.org/article/d33413c6c13241c5b627404f177fbf5d
Autor:
Younghun Han, Jinyoung Byun, Catherine Zhu, Ryan Sun, Julia Y. Roh, Heather J. Cordell, Hyun-Sung Lee, Vikram R. Shaw, Sung Wook Kang, Javad Razjouyan, Matthew A. Cooley, Manal M. Hassan, Katherine A. Siminovitch, Trine Folseraas, David Ellinghaus, Annika Bergquist, Simon M. Rushbrook, Andre Franke, Tom H. Karlsen, Konstantinos N. Lazaridis, The International PSC Study Group, Katherine A. McGlynn, Lewis R. Roberts, Christopher I. Amos
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-13 (2023)
The genetic basis of primary sclerosing cholangitis has only been partially uncovered. Here, the authors perform a multitrait genome-wide association study to provide insight into the genetic etiology of primary sclerosing cholangitis risk and possib
Externí odkaz:
https://doaj.org/article/a3158eab38c04ddbaa6e7834c504e9f6
Autor:
Fadl A. Zeineddine, Mohammad A. Zeineddine, Abdelrahman Yousef, Yue Gu, Saikat Chowdhury, Arvind Dasari, Ryan W. Huey, Benny Johnson, Bryan Kee, Michael S. Lee, Maria Pia Morelli, Van K. Morris, Michael J. Overman, Christine Parseghian, Kanwal Raghav, Jason Willis, Robert A. Wolff, Yoshikuni Kawaguchi, Jean-Nicolas Vauthey, Ryan Sun, Scott Kopetz, John Paul Shen
Publikováno v:
npj Precision Oncology, Vol 7, Iss 1, Pp 1-9 (2023)
Abstract Over the past two decades of successive clinical trials in metastatic colorectal cancer (CRC), the median overall survival of both control and experimental arms has steadily improved. However, the incremental change in survival for metastati
Externí odkaz:
https://doaj.org/article/7b9f437bc4574113bf04a302f7650255
Autor:
Tushar Patni, Chun-Teh Lee, Yimei Li, Sue Kaste, Liang Zhu, Ryan Sun, Melissa M. Hudson, Kirsten K. Ness, Ana Neumann, Leslie L. Robison
Publikováno v:
BMC Oral Health, Vol 23, Iss 1, Pp 1-11 (2023)
Abstract Background Survivors of childhood cancer are at risk for therapy-related dental diseases. The purpose of the study was to investigate the associations between clinical, socioeconomic, and demographic factors and oral diseases in the St. Jude
Externí odkaz:
https://doaj.org/article/a5b1b792e030401ab5f3e98434588e07
Autor:
Hua Wang, Rohan Moniruzzaman, Lei Li, Baoan Ji, Yi Liu, Xiangsheng Zuo, Reza Abbasgholizadeh, Jun Zhao, Guangchao Liu, Ruiqi Wang, Hongli Tang, Ryan Sun, Xiaoping Su, Tse-Hua Tan, Anirban Maitra, Huamin Wang
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 12 (2023)
Ras plays an essential role in the development of acinar-to-ductal metaplasia (ADM) and pancreatic ductal adenocarcinoma (PDAC). However, mutant Kras is an inefficient driver for PDAC development. The mechanisms of the switching from low Ras activity
Externí odkaz:
https://doaj.org/article/387208fdd37b4d7fa8c9d084ec53be4a
Autor:
Guangchun Han, Guoliang Yang, Dapeng Hao, Yang Lu, Kyaw Thein, Benjamin S. Simpson, Jianfeng Chen, Ryan Sun, Omar Alhalabi, Ruiping Wang, Minghao Dang, Enyu Dai, Shaojun Zhang, Fengqi Nie, Shuangtao Zhao, Charles Guo, Ameer Hamza, Bogdan Czerniak, Chao Cheng, Arlene Siefker-Radtke, Krishna Bhat, Andrew Futreal, Guang Peng, Jennifer Wargo, Weiyi Peng, Humam Kadara, Jaffer Ajani, Charles Swanton, Kevin Litchfield, Jordi Rodon Ahnert, Jianjun Gao, Linghua Wang
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-19 (2021)
The molecular mechanisms of resistance to immune checkpoint therapy remain elusive. Here, the authors perform immunogenomic analysis of TCGA data and data from clinical trials for antiPD-1/PD-L1 therapy and highlight the association of 9p21 loss with
Externí odkaz:
https://doaj.org/article/f000b69e3fbd4f02bc414de145aab9e8
Autor:
Nour Abuhadra, Ryan Sun, Clinton Yam, Gaiane M. Rauch, Qingqing Ding, Bora Lim, Alastair M. Thompson, Elizabeth A. Mittendorf, Beatriz E. Adrada, Senthil Damodaran, Kiran Virani, Jason White, Elizabeth Ravenberg, Jia Sun, Jaihee Choi, Rosalind Candelaria, Banu Arun, Naoto T. Ueno, Lumarie Santiago, Sadia Saleem, Sausan Abouharb, Rashmi K. Murthy, Nuhad Ibrahim, Aysegul Sahin, Vicente Valero, William Fraser Symmans, Jennifer K. Litton, Debu Tripathy, Stacy Moulder, Lei Huo
Publikováno v:
Cancers, Vol 15, Iss 13, p 3275 (2023)
High stromal tumor-infiltrating lymphocytes (sTILs) are associated with improved pathologic complete response (pCR) in triple-negative breast cancer (TNBC). We hypothesize that integrating high sTILs and additional clinicopathologic features associat
Externí odkaz:
https://doaj.org/article/27f5149e61a341b7a9347399b211d86d
Autor:
Mingxuan Xu, Coya Tapia, Joud Hajjar, Sharjeel Sabir, Rivka Colen, Priyadharsini Nagarajan, Phyu P. Aung, Jing Gong, Jordi Rodon, Siqing Fu, Bettzy Stephen, Sinchita Roy-Chowdhuri, Hung Le, Vincent Yang, Abdulrazzak Zarifa, Mohamed Elsayed Abdelsalam, Anuja Jhingran, Milind Javle, Shubham Pant, Brett Carter, Denai R. Milton, Ryan Sun, Daniel D. Karp, Eugene Jon Koay, Yali Yang, Ignacio I. Wistuba, Patrick Hwu, Funda Meric-Bernstam, Aung Naing
Publikováno v:
Journal of Immunotherapy and Precision Oncology, Pp 45-52 (2021)
Introduction: For maximum utility of molecular characterization by next-generation sequencing (NGS) and better understanding of tumor microenvironment with immune correlates analysis, biopsy specimens must yield adequate tumor tissue, and sequential
Externí odkaz:
https://doaj.org/article/92b80aa5eeec4ee281f88d023127d548