Zobrazeno 1 - 10
of 19
pro vyhledávání: '"Ryan Stuchbery"'
Autor:
Stefano Mangiola, Patrick McCoy, Martin Modrak, Fernando Souza-Fonseca-Guimaraes, Daniel Blashki, Ryan Stuchbery, Simon P. Keam, Michael Kerger, Ken Chow, Chayanica Nasa, Melanie Le Page, Natalie Lister, Simon Monard, Justin Peters, Phil Dundee, Scott G. Williams, Anthony J. Costello, Paul J. Neeson, Bhupinder Pal, Nicholas D. Huntington, Niall M. Corcoran, Anthony T. Papenfuss, Christopher M. Hovens
Publikováno v:
BMC Cancer, Vol 21, Iss 1, Pp 1-18 (2021)
Abstract Background Prostate cancer is caused by genomic aberrations in normal epithelial cells, however clinical translation of findings from analyses of cancer cells alone has been very limited. A deeper understanding of the tumour microenvironment
Externí odkaz:
https://doaj.org/article/6df753fdc4cc463099e2cb3f0e220186
Autor:
Stefano Mangiola, Ryan Stuchbery, Patrick McCoy, Ken Chow, Natalie Kurganovs, Michael Kerger, Anthony Papenfuss, Christopher M Hovens, Niall M Corcoran
Publikováno v:
Endocrine Connections, Vol 8, Iss 5, Pp 547-558 (2019)
Prostate cancer is a leading cause of morbidity and cancer-related death worldwide. Androgen deprivation therapy (ADT) is the cornerstone of management for advanced disease. The use of these therapies is associated with multiple side effects, includi
Externí odkaz:
https://doaj.org/article/1cdeccad257a49f6bf735622768dbe59
Autor:
Stefano Mangiola, Jeremy Grummet, Michael Kerger, Paul Ruljancich, Ryan Stuchbery, David Clarke, Justin S. Peters, Andrew Ryan, Niall M. Corcoran, Phillip Parente, Nicholas Howard, Christopher M. Hovens, Natalie Kurganovs, Sam Norden, Anthony J. Costello, Anne Ngyuen, Corrina A Grima, Patrick McCoy, Geoff Macintyre, Philip Dundee, Marek Cmero, Ken Chow
Publikováno v:
JCO Precision Oncology
PURPOSE Androgen receptor (AR) signaling is important in prostate cancer progression, and therapies that target this pathway have been the mainstay of treatment for advanced disease for over 70 years. Tumors eventually progress despite castration thr
Autor:
Natalie Kurganovs, Patrick McCoy, Michael Kerger, Niall M. Corcoran, Stefano Mangiola, Ryan Stuchbery, Ken Chow, Anthony T. Papenfuss, Christopher M. Hovens
Publikováno v:
Endocrine Connections
Endocrine Connections, Vol 8, Iss 5, Pp 547-558 (2019)
Endocrine Connections, Vol 8, Iss 5, Pp 547-558 (2019)
Prostate cancer is a leading cause of morbidity and cancer-related death worldwide. Androgen deprivation therapy (ADT) is the cornerstone of management for advanced disease. The use of these therapies is associated with multiple side effects, includi
Autor:
Izhak Haviv, Michael J Clarkson, Michael Kerger, Ryan Stuchbery, Niall M. Corcoran, Ryan Hutchinson, Andrew M. Ryan, Anthony J. Costello, Marek Cmero, Sebastian Lunke, Geoff Macintyre, Ben Tran, Ken Chow, Stefano Mangiola, Christopher M. Hovens, Patrick Mccoy, Natalie Kurganovs, Peter Georgeson, Matthew K.H. Hong, Bernard J. Pope
Publikováno v:
Prostate cancer and prostatic diseases. 24(4)
Recent publications have shown patients with defects in the DNA mismatch repair (MMR) pathway driven by either MSH2 or MSH6 loss experience a significant increase in the incidence of prostate cancer. Moreover, this increased incidence of prostate can
Autor:
Daniel Blashki, Ryan Stuchbery, Niall M. Corcoran, Chayanica Nasa, Anthony J. Costello, Stefano Mangiola, Fernando Souza-Fonseca-Guimaraes, Ken Chow, Simon Monard, Martin Modrak, Scott Williams, Paul J Neeson, Melanie Le Page, Christopher M. Hovens, Nicholas D. Huntington, Bhupinder Pal, Anthony T. Papenfuss, Patrick McCoy, Michael Kerger, Phil Dundee, Justin S. Peters, Natalie Lister, Simon P. Keam
Prostate cancer is caused by genomic aberrations in normal epithelial cells, however clinical translation of findings from analyses of cancer cells alone has been very limited. A deeper understanding of the tumour microenvironment is needed to identi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c981e524c824f88f08b0ad621842fcd8
https://doi.org/10.1101/2020.03.16.993162
https://doi.org/10.1101/2020.03.16.993162
Publikováno v:
World Journal of Urology. 37:2549-2555
To review the current understanding and recent developments regarding the concept of oligometastases in hormone-sensitive prostate cancer. A comprehensive literature search of electronic databases, including PubMed and Embase was conducted for the se
Autor:
Pia Herrera, Christopher M. Hovens, Justin S. Peters, Ryan Stuchbery, Niall M. Corcoran, Anthony J. Costello, Ken Chow
Publikováno v:
BJU International. 123:976-984
To characterise the pattern of late biochemical recurrence (BCR) in the largest contemporary cohort of patients with localised prostate cancer treated with radical prostatectomy (RP) in the active surveillance era.Consecutive patients who underwent R
Autor:
Pia Herrera, Ryan Stuchbery, Justin S. Peters, Niall M. Corcoran, Christopher M. Hovens, Anthony J. Costello, Ken Chow
Publikováno v:
Journal of Urology. 201
Publikováno v:
Clinical Cancer Research. 22:3132-3137
The maintenance of a pristine genome, free from errors, is necessary to prevent cellular transformation and degeneration. When errors in DNA are detected, DNA damage repair (DDR) genes and their regulators are activated to effect repair. When these D