Zobrazeno 1 - 10
of 22
pro vyhledávání: '"Ryan S. Teller"'
Autor:
Yongchao Su, Ryan S. Teller, Wei Xu, Varsolona Richard J, Daniel Skomski, Seth P. Forster, Stephanie E. Barrett, Jingtao Zhang
Publikováno v:
Molecular Pharmaceutics. 17:2874-2881
The emergence of new active pharmaceutical ingredient (API) polymorphs in pharmaceutical development presents significant risks. Even with thorough polymorph screening, new pathways toward alternate crystal phases can present themselves over the cour
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e711613fa8510e21a95b5ac8f4be5cf
https://doi.org/10.1021/acs.molpharmaceut.0c00316
https://doi.org/10.1021/acs.molpharmaceut.0c00316
Autor:
Graciela Terife, Ryan S. Teller, David White, Ashley R. Johnson, Michael Lowinger, Stephanie E. Barrett, Seth P. Forster
Publikováno v:
Expert opinion on drug delivery. 18(5)
Introduction: Drug eluting implants offer patient convenience and improved compliance through less frequent dosing, eliminating repeated, painful injections and providing localized, site specific d...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6dbc3378e4021dea8836fb0e1649faa3
https://pubmed.ncbi.nlm.nih.gov/33275066
https://pubmed.ncbi.nlm.nih.gov/33275066
Autor:
Alena Bensussan, Roy Helmy, Bindesh Shrestha, Hernando J. Olivos, Vivek Shah, Elizabeth E. Pierson, William P. Forrest, Ryan S. Teller, Anthony J. Midey, Seth P. Forster
Publikováno v:
Pharmaceutical Research. 37
Desorption electrospray ionization mass spectrometry imaging (DESI-MSI) coupled with gas-phase ion mobility spectrometry was used to characterize the drug distribution in polymeric implants before and after exposure to accelerated in vitro release (I
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b3987547d67cbf25a8f0ff3451cf677a
https://doi.org/10.1007/s11095-020-02823-x
https://doi.org/10.1007/s11095-020-02823-x
Autor:
Amy C. Doty, Seth P. Forster, Christopher T. John, Wei Xu, Daniel Skomski, Ryan S. Teller, Stephanie E. Barrett, Yongchao Su, Zhen Liu
Publikováno v:
Journal of pharmaceutical sciences. 109(9)
In pharmaceutical development alternative drug delivery modalities are being increasingly employed. One example is an implant, which achieves gradual drug release in patients over a period of many months or years. Due to the complexity of these long-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6e77dfd4f19c94e9abbf856e8459b47e
https://pubmed.ncbi.nlm.nih.gov/32534030
https://pubmed.ncbi.nlm.nih.gov/32534030
Autor:
Jining Zhang, Priya Srinivasan, Betsy C. Herold, Patrick F. Kiser, Chuong Dinh, James M. Smith, Ryan S. Teller, Janet M. McNicholl
Publikováno v:
Journal of Medical Primatology. 46:129-136
Background Intravaginal rings (IVR) for HIV prevention will likely be used by women on depot medroxyprogesterone acetate (DMPA) hormonal contraception. We used pigtailed macaques to evaluate the effects of DMPA on tenofovir disoproxil fumarate (TDF)
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9cf5a66f5f19077060e6b33d8ab4ab67
https://doi.org/10.1111/jmp.12299
https://doi.org/10.1111/jmp.12299
Autor:
Megan A. Mackey, Takayuki Tsuchiya, Marian E. Gindy, Steven J. Henry, Li Li, Zhen Yang, Gregory J. Doto, Ryan S. Teller, Lee J. Klein, Stephanie E. Barrett, Michael P. Ruth, Seth P. Forster
Publikováno v:
European journal of pharmaceutical sciences : official journal of the European Federation for Pharmaceutical Sciences. 136
Alternative formulations of entecavir, a once daily oral hepatitis B antiretroviral, may improve treatment adherence by patients. We explored the use of biocompatible polymers to control entecavir dissolution in two formats suitable for subcutaneous
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2764c303f546c6a0dbfa292d1bdfa2f4
https://pubmed.ncbi.nlm.nih.gov/31212018
https://pubmed.ncbi.nlm.nih.gov/31212018
Autor:
Igal Szleifer, Patrick F. Kiser, David C. Malaspina, Rachna Rastogi, Justin T. Clark, Ryan S. Teller
Publikováno v:
Journal of Controlled Release. 224:176-183
Intravaginal ring technology is generally limited to releasing low molecular weight species that can diffuse through the ring elastomer. To increase the diversity of drugs that can be delivered from intravaginal rings, we designed an IVR that contain
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4185a21973d40d5c839ece65d26a7ea2
https://doi.org/10.1016/j.jconrel.2015.12.035
https://doi.org/10.1016/j.jconrel.2015.12.035
Autor:
Antong Chen, Roberto Irizarry, Megan A. Mackey, Seth P. Forster, Daniel Skomski, Ryan S. Teller, Li Li
Publikováno v:
Industrial & Engineering Chemistry Research.
This work develops a mechanistic understanding and a simplified model to understand changes in drug release profiles of an active pharmaceutical ingredient in a long-acting parenteral polymer formu...
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7e9cdfc83dc0e2e5ad107d427e85bd49
https://doi.org/10.1021/acs.iecr.8b02806
https://doi.org/10.1021/acs.iecr.8b02806
Autor:
Yongchao Su, Wei Xu, Seth P. Forster, Ryan S. Teller, Andrew T. Francis, Ronald L. Smith, Jesse Kuiper, Timothy Rhodes, Dan Fu, Tai T. Nguyen, Matthew S. Lamm
Publikováno v:
Molecular pharmaceutics. 15(12)
Localized drug delivery systems (DDSs) provide therapeutic levels of drug agent while mitigating side effects of systemic delivery. These systems offer controlled release over extended periods of time making them attractive therapies. Monitoring drug
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::134441913e927007e19574f97a61ccd6
https://pubmed.ncbi.nlm.nih.gov/30362772
https://pubmed.ncbi.nlm.nih.gov/30362772
Autor:
Seth P. Forster, José A. Lebrón, Jay A. Grobler, Ryan S. Teller, Kerry L. Fillgrove, Stephanie E. Barrett, Zhen Yang, Zhen Liu, Bing Lu, Gregory J. Doto, Megan A. Mackey, Li Sun, Sandra L. Wood, Li Li, Rosa I. Sanchez, Marian E. Gindy, Daniel Skomski, Tao Niu
Regimen adherence remains a major hurdle to the success of daily oral drug regimens for the treatment and prevention of human immunodeficiency virus (HIV) infection. Long-acting drug formulations requiring less-frequent dosing offer an opportunity to
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::adae5b715cb6db226c3e09eb65164dfd
https://europepmc.org/articles/PMC6153840/
https://europepmc.org/articles/PMC6153840/
