Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Ryan S. Pawell"'
Autor:
Justin A. Jarrell, Brandon J. Sytsma, Leah H. Wilson, Fong L. Pan, Katherine H. W. J. Lau, Giles T. S. Kirby, Adrian A. Lievano, Ryan S. Pawell
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Abstract Microfluidic vortex shedding (µVS) can rapidly deliver mRNA to T cells with high yield and minimal perturbation of the cell state. The mechanistic underpinning of µVS intracellular delivery remains undefined and µVS-Cas9 genome editing re
Externí odkaz:
https://doaj.org/article/600c810d0b0d45d6a04aaa482fec0696
Autor:
Brandon J. Sytsma, Ryan S. Pawell, Adrian A. Lievano, Leah H. Wilson, Justin A. Jarrell, Giles T. S. Kirby, Katherine H.W.J. Lau, Fong L. Pan
Publikováno v:
Scientific Reports
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Scientific Reports, Vol 11, Iss 1, Pp 1-13 (2021)
Microfluidic vortex shedding (µVS) can rapidly deliver mRNA to T cells with high yield and minimal perturbation of the cell state. The mechanistic underpinning of µVS intracellular delivery remains undefined and µVS-Cas9 genome editing requires fu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7a2f654677a3cb4bc72971847c63cea1
http://europepmc.org/articles/PMC8175688
http://europepmc.org/articles/PMC8175688
Autor:
Ryan S. Pawell, Brandon J. Sytsma, Giles T. S. Kirby, Katherine H.W.J. Lau, Leah H. Wilson, Justin A. Jarrell, Adrian A. Lievano, Fong L. Pan
Microfluidic vortex shedding (μVS) can rapidly deliver mRNA to T cells with high yield. The mechanistic underpinning of μVS intracellular delivery remains undefined and μVS-Cas9 genome editing requires further studies. Herein, we evaluated a serie
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::1a767304f9ea837ea26931ce0e88d5c0
https://doi.org/10.1101/2020.02.26.960336
https://doi.org/10.1101/2020.02.26.960336
Autor:
Julyana Acevedo, Amy A. Twite, Moein Navvab Kashani, Adrian A. Lievano, Justin A. Jarrell, Craig Priest, Katherine H.W.J. Lau, David Gottlieb, Ryan S. Pawell, Jorge Nieva
Publikováno v:
Scientific Reports
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Scientific Reports, Vol 9, Iss 1, Pp 1-11 (2019)
Intracellular delivery is a critical process in biology and medicine. During intracellular delivery, different constructs (e.g., functional macromolecules such as DNA, RNA, and protein, and various complexes) are delivered across the cell membrane an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7f81c29d993471756ead7d1297b4f531
Publikováno v:
Microfluidics and Nanofluidics. 18:657-665
Microfluidic devices promise to significantly advance the field of medicine by providing diagnostic tools that may be administered at the point-of-care (POC). Currently, a major barrier to entry for POC microfluidic diagnostic technologies is part qu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::90b2c887a97728701faa596cac63b037
https://doi.org/10.1007/s10404-014-1464-1
https://doi.org/10.1007/s10404-014-1464-1
Publikováno v:
Applied Mechanics and Materials. 553:367-372
Micropost arrays serve as a plaform for the next generation of diagnostic devices. These arrays are found in microfluidic devices for peripheral blood-based diagnostics and metastatic cancer management. The function and performance of these devices i
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ca41ed12ea118c0bbab6a4526997ed0a
https://doi.org/10.4028/www.scientific.net/amm.553.367
https://doi.org/10.4028/www.scientific.net/amm.553.367
Publikováno v:
Applied Mechanics and Materials. 553:162-167
Image analysis can play an important role in the validation and analysis of computational studies. Computational Fluid Dynamics (CFD) compared to experiments, has the advantage of detailed information analysis across the domain of interest. However,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::34cd488825f3bd5c85bcedc68f6b4856
https://doi.org/10.4028/www.scientific.net/amm.553.162
https://doi.org/10.4028/www.scientific.net/amm.553.162
Publikováno v:
ASME 2013 4th International Conference on Micro/Nanoscale Heat and Mass Transfer.
Microfluidic particle separation technologies are useful for enriching rare cell populations for academic and clinical purposes. In order to separate particles based on size, deterministic lateral displacement (DLD) arrays are designed assuming that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::24474f0861b71d10839d0ef55228f291
https://doi.org/10.1115/mnhmt2013-22035
https://doi.org/10.1115/mnhmt2013-22035
Publikováno v:
Biomicrofluidics. 7(5)
Deterministic lateral displacement (DLD) is a microfluidic size-based particle separation or filter technology with applications in cell separation and enrichment. Currently, there are no cost-effective manufacturing methods for this promising microf
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5e70714a1f16836e910f697a26f3bf22
https://pubmed.ncbi.nlm.nih.gov/24223084
https://pubmed.ncbi.nlm.nih.gov/24223084
Publikováno v:
Biomicrofluidics. 7:059901
The acknowledgments in the original paper1 are incomplete. The following statement should be included: “The authors thank the Australian National Fabrication Facility for the deep reactive ion etching.”
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9a73f3405e1ee2149fda77e9d62ed614
https://doi.org/10.1063/1.4827599
https://doi.org/10.1063/1.4827599