Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice[S]

Autor: Ryan S. Lim, Adelheid Kratzer, Nicholas P. Barry, Shinobu Miyazaki-Anzai, Makoto Miyazaki, William W. Mantulin, Moshe Levi, Eric O. Potma, Bruce J. Tromberg

Publikováno v: Journal of Lipid Research, Vol 51, Iss 7, Pp 1729-1737 (2010)

We characterized several cellular and structural features of early stage Type II/III atherosclerotic plaques in an established model of atherosclerosis—the ApoE-deficient mouse—by using a multimodal, coregistered imaging system that integrates th

Externí odkaz: https://doaj.org/article/34dff783e53c463da93d61042bc70185

Identification of cholesterol crystals in plaques of atherosclerotic mice using hyperspectral CARS imaging

Autor: Eric O. Potma, Makoto Miyazaki, Shinobu Miyazaki-Anzai, Bruce J. Tromberg, Moshe Levi, Jeffrey L. Suhalim, Ryan S. Lim

Publikováno v: Journal of Lipid Research, Vol 52, Iss 12, Pp 2177-2186 (2011)
Lim, RS; Suhalim, JL; Miyazaki-Anzai, S; Miyazaki, M; Levi, M; Potma, EO; et al.(2011). Identification of cholesterol crystals in plaques of atherosclerotic mice using hyperspectral CARS imaging. Journal of Lipid Research, 52(12), 2177-2186. doi: 10.1194/jlr.M018077. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7xs0x3zw

The accumulation of lipids, including cholesterol, in the arterial wall plays a key role in the pathogenesis of atherosclerosis. Although several advances have been made in the detection and imaging of these lipid structures in plaque lesions, their

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2c8e47ac09a172f2a2fb8a59d5a890b6
http://www.sciencedirect.com/science/article/pii/S0022227520408223

Evaluation of Fuel-efficient Sun Search Slew Rates for the Cassini Spacecraft in the Cassini Solstice Mission

Autor: Ryan S. Lim

Publikováno v: AIAA Guidance, Navigation, and Control Conference.

As NASA’s Cassini spacecraft continues to explore the Saturnian system in the second extended mission named the Solstice mission, the spacecraft operators have increased efforts to minimize hydrazine consumption to ensure the mission’s success th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::203035373539809218601c9ba3ba2931
https://doi.org/10.2514/6.2012-4608

Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice

Autor: Shinobu Miyazaki-Anzai, Adelheid Kratzer, Moshe Levi, Makoto Miyazaki, Nicholas P. Barry, Bruce J. Tromberg, Eric O. Potma, William W. Mantulin, Ryan S. Lim

Publikováno v: Lim, RS; Kratzer, A; Barry, NP; Miyazaki-Anzai, S; Miyazaki, M; Mantulin, WW; et al.(2010). Multimodal CARS microscopy determination of the impact of diet on macrophage infiltration and lipid accumulation on plaque formation in ApoE-deficient mice. Journal of Lipid Research, 51(7), 1729-1737. doi: 10.1194/jlr.M003616. UC Irvine: Retrieved from: http://www.escholarship.org/uc/item/7bb9b8kv
Journal of Lipid Research, Vol 51, Iss 7, Pp 1729-1737 (2010)

We characterized several cellular and structural features of early stage Type II/III atherosclerotic plaques in an established model of atherosclerosis - the ApoE-deficient mouse - by using a multimodal, coregistered imaging system that integrates th

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29bc7a39569b3c1d8cc4458f7eee6bb1
https://pubmed.ncbi.nlm.nih.gov/20208058

Abstract 899: Combination of PI3K and MEK inhibitor chemosensitivity in human tumor explants and cell lines using the Mosaic Blue assay and relationship to biomarkers by immunohistochemistry

Autor: Gela C. Sia, Christopher A. Kerfoot, Jianping Zheng, Eric Olsen, Ryan S. Lim, Sherif K. Girees, Patricia A. Cash, Lisa M. Dauffenbach

Publikováno v: Cancer Research. 74:899-899

The PI3K and MEK pathways promote tumor cell survival through a variety of downstream signals and are commonly explored in cancer research. Many agents are in clinical development and new evidence suggests that a combination of these inhibitors may b

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::90b50a9797371b71fb80673e3c30633a
https://doi.org/10.1158/1538-7445.am2014-899