Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Ryan Rossner"'
Autor:
Haeri Choi, Sung Chun Cho, Young Wan Ha, Billie Ocampo, Shirley Park, Shiwen Chen, Christopher F. Bennett, Jeehae Han, Ryan Rossner, Jong-Sun Kang, Yun-ll Lee, Sang Chul Park, Matt Kaeberlein
Publikováno v:
Translational Medicine of Aging, Vol 3, Iss , Pp 64-69 (2019)
The antibiotic diaminodiphenyl sulfone (DDS) is used in combination with other antibiotics as a first line treatment for leprosy. DDS has been previously reported to extend lifespan in Caenorhabditis elegans through inhibition of pyruvate kinase and
Externí odkaz:
https://doaj.org/article/703a38fb11dc4f9488f12d04f06a6285
Autor:
Christopher F Bennett, Jane J Kwon, Christine Chen, Joshua Russell, Kathlyn Acosta, Nikolay Burnaevskiy, Matthew M Crane, Alessandro Bitto, Helen Vander Wende, Marissa Simko, Victor Pineda, Ryan Rossner, Brian M Wasko, Haeri Choi, Shiwen Chen, Shirley Park, Gholamali Jafari, Bryan Sands, Carissa Perez Olsen, Alexander R Mendenhall, Philip G Morgan, Matt Kaeberlein
Publikováno v:
PLoS Genetics, Vol 13, Iss 3, p e1006695 (2017)
Mitochondrial dysfunction can increase oxidative stress and extend lifespan in Caenorhabditis elegans. Homeostatic mechanisms exist to cope with disruptions to mitochondrial function that promote cellular health and organismal longevity. Previously,
Externí odkaz:
https://doaj.org/article/16244a054fa74a9d8488d864fa5e9844
Autor:
Shirley Park, Billie R. Ocampo, Matt Kaeberlein, Sang Chul Park, Shiwen Chen, Young Wan Ha, Ryan Rossner, Yun-ll Lee, Christopher F. Bennett, Jeehae Han, Haeri Choi, Jong-Sun Kang, Sung Chun Cho
Publikováno v:
Translational Medicine of Aging, Vol 3, Iss, Pp 64-69 (2019)
The antibiotic diaminodiphenyl sulfone (DDS) is used in combination with other antibiotics as a first line treatment for leprosy. DDS has been previously reported to extend lifespan in Caenorhabditis elegans through inhibition of pyruvate kinase and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbf06fa63dc5e68e87daf87a62bd3a1b
http://www.sciencedirect.com/science/article/pii/S2468501119300045
http://www.sciencedirect.com/science/article/pii/S2468501119300045
Publikováno v:
Journal of Biological Chemistry. 292:11138-11146
Flavin-containing monooxygenases (FMOs) are primarily studied as xenobiotic metabolizing enzymes with a prominent role in drug metabolism. In contrast, endogenous functions and substrates of FMOs are less well understood. A growing body of recent evi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe258257f3e39ee8dd6e96fb1df9bee3
https://doi.org/10.1074/jbc.r117.779678
https://doi.org/10.1074/jbc.r117.779678
FLAVIN-CONTAINING MONOOXYGENASES (FMOS): LONGEVITY-PROMOTING ENZYMES OR ATHEROSCLEROSIS RISK FACTOR?
Autor:
Ryan Rossner, Matt Kaeberlein
Publikováno v:
Innovation in Aging
Since their discovery in 1970, flavin-containing monooxygenases (FMOs) have been studied as Phase 1 xenobiotic metabolizing enzymes that act on sulfur- and nitrogen-containing small molecules. In 2015, we demonstrated that C. elegans (worm) fmo-2 was
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fdb3c073efafca0715c250473549477e
https://doi.org/10.1093/geroni/igz038.3497
https://doi.org/10.1093/geroni/igz038.3497
Autor:
Ryan Rossner, Marissa Fletcher, Matt Kaeberlein, Scott F. Leiser, Alison Leonard, Melissa Primitivo, Fresnida J. Ramos, Dana L. Miller, Nicholas D. Rintala, Hillary Miller
Publikováno v:
Science. 350:1375-1378
Stabilization of the hypoxia-inducible factor 1 (HIF-1) increases life span and health span in nematodes through an unknown mechanism. We report that neuronal stabilization of HIF-1 mediates these effects in Caenorhabditis elegans through a cell nona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b888b3e0f7ca89095bf93c1b812d6900
https://doi.org/10.1126/science.aac9257
https://doi.org/10.1126/science.aac9257
Autor:
Alexander Mendenhall, Haeri Choi, Victor V. Pineda, Jane J. Kwon, Matthew M. Crane, Philip G. Morgan, Christopher F. Bennett, Joshua Russell, Shirley Park, Nikolay Burnaevskiy, Bryan Sands, Helen Vander Wende, Brian M. Wasko, Ryan Rossner, Carissa Perez Olsen, Matt Kaeberlein, Kathlyn Acosta, Alessandro Bitto, Gholamali Jafari, Marissa Simko, Shiwen Chen, Christine Chen
Publikováno v:
PLoS Genetics
PLoS Genetics, Vol 13, Iss 3, p e1006695 (2017)
PLoS Genetics, Vol 13, Iss 3, p e1006695 (2017)
Mitochondrial dysfunction can increase oxidative stress and extend lifespan in Caenorhabditis elegans. Homeostatic mechanisms exist to cope with disruptions to mitochondrial function that promote cellular health and organismal longevity. Previously,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538fcf7069a6ce045c86f01d780fb362
http://europepmc.org/articles/PMC5389855
http://europepmc.org/articles/PMC5389855
Publikováno v:
Worm. 5(2)
Stabilization of the hypoxia-inducible factor 1 (HIF-1) increases life span and health span in nematodes through an unknown mechanism. We report that neuronal stabilization of HIF-1 mediates these effects in Caenorhabditis elegans through a cell nona
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::51d826ab03c67bacd47ec477592a6b51
https://pubmed.ncbi.nlm.nih.gov/26586189
https://pubmed.ncbi.nlm.nih.gov/26586189