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of 4
pro vyhledávání: '"Ryan R. Wyrofsky"'
Autor:
Ryan R. Wyrofsky, Beverly A.S. Reyes, Xiao-Yan Zhang, Seema Bhatnagar, Lynn G. Kirby, Elisabeth J. Van Bockstaele
Publikováno v:
Neurobiology of Stress, Vol 11, Iss , Pp - (2019)
The endocannabinoid (eCB) system has been implicated in a variety of physiological functions due to abundant expression of its receptors and endogenous ligands in the central nervous system. Substantial progress has been made in understanding how the
Externí odkaz:
https://doaj.org/article/3c2fc60301c041a7a7d82abc90519fdf
Publikováno v:
Brain Struct Funct
The noradrenergic system has been shown to play a key role in the regulation of stress responses, arousal, mood, and emotional states. Corticotropin-releasing factor (CRF) is a primary mediator of stress-induced activation of noradrenergic neurons in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::538057078655c4da5dcb6fb4e82a9cc8
https://doi.org/10.1007/s00429-017-1381-7
https://doi.org/10.1007/s00429-017-1381-7
Publikováno v:
The European journal of neuroscience. 48(5)
Cannabinoids are capable of modulating mood, arousal, cognition and behavior, in part via their effects on the noradrenergic nucleus locus coeruleus (LC). Dysregulation of LC signaling and norepinephrine (NE) efflux in the medial prefrontal cortex (m
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::924e98f931860e454481a00683a6efec
https://pubmed.ncbi.nlm.nih.gov/30758091
https://pubmed.ncbi.nlm.nih.gov/30758091
Drug discovery strategies that focus on the endocannabinoid signaling system in psychiatric disease.
Autor:
Wyrofsky R; Drexel University, Department of Pharmacology and Physiology , Mail Stop 400, New College Building, 245 N. 15th Street, Philadelphia, PA 19102 , USA rrw47@drexel.edu., McGonigle P, Van Bockstaele EJ
Publikováno v:
Expert opinion on drug discovery [Expert Opin Drug Discov] 2015 Jan; Vol. 10 (1), pp. 17-36. Date of Electronic Publication: 2014 Dec 09.