Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Ryan R. Hughes"'
Autor:
Jon S. Thorson, Jamie Horn, Khaled A. Shaaban, S. Randal Voss, Chang-Guo Zhan, Larissa V. Ponomareva, Markos Leggas, Chunhui Zhang, Ryan R. Hughes
Publikováno v:
Chembiochem
Herein we describe the ability of the permissive glycosyltransferase (GT) OleD Loki to convert a diverse set of > 15 histone deacetylase (HDAC) inhibitors (HDACis) into their corresponding hydroxamate glycosyl esters. Representative glycosyl esters w
Autor:
Manjula Sunkara, Jon S. Thorson, Yinan Zhang, Samantha A. Scott, Sherif I. Elshahawi, Ryan R. Hughes, Larissa V. Ponomareva, Jianjun Zhang, Khaled A. Shaaban, Andrew J. Morris, Meredith A. Saunders, Mark A. Prendergast, Sydney R. Winchester
Publikováno v:
Journal of Natural Products. 80:12-18
The assessment of glycosyl-scanning to expand the molecular and functional diversity of metabolites from the underground coal mine fire-associated Streptomyces sp. RM-14-6 is reported. Using the engineered glycosyltransferase OleD Loki and a 2-chloro
Autor:
Khaled A. Shaaban, Jon S. Thorson, Ryan R. Hughes, George N. Phillips, Jianjun Zhang, Hongnan Cao
Publikováno v:
Chembiochem : a European journal of chemical biology. 18(4)
We describe the ability of an engineered glycosyltransferase (OleD Loki) to catalyze the N-glycosylation of tertiary-amine-containing drugs and trichostatin hydroxamate glycosyl ester formation. As such, this study highlights the first bacterial mode
Autor:
Jon S. Thorson, Ryan R. Hughes, Maoquan Zhou, Shanteri Singh, Andrew J. Morris, Jianjun Zhang, Manjula Sunkara
Publikováno v:
Chembiochem : a European journal of chemical biology. 15(5)
A set of 2-chloro-4-nitrophenyl glucosamino/xylosaminosides were synthesized and assessed as potential substrates in the context of glycosyltransferase-catalyzed formation of the corresponding UDP/TDP-α-D-glucosamino-/xylosaminosugars and single ves
Autor:
Glockzin K; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States., Meneely KM; Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States., Hughes R; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States., Maatouk SW; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States., Piña GE; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States., Suthagar K; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand., Clinch K; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand., Buckler JN; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand., Lamb AL; Department of Chemistry, University of Texas at San Antonio, One UTSA Circle, San Antonio, Texas 78249, United States., Tyler PC; Ferrier Research Institute, Victoria University of Wellington, Gracefield Research Centre, 69 Gracefield Road, Gracefield, Lower Hutt 5010, New Zealand., Meek TD; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States., Katzfuss A; Department of Biochemistry and Biophysics, Texas A&M University, 300 Olsen Boulevard, College Station, Texas 77843-2128, United States.
Publikováno v:
Biochemistry [Biochemistry] 2023 Jul 18; Vol. 62 (14), pp. 2182-2201. Date of Electronic Publication: 2023 Jul 07.
Autor:
Morris BB; Virginia Commonwealth University School of Medicine, Department of Health Behavior and Policy, Richmond, Virginia. Electronic address: bemorris@wakehealth.edu., Hughes R; Wake Forest School of Medicine, Department of Radiation Oncology, Winston-Salem, North Carolina., Fields EC; Virginia Commonwealth University School of Medicine, Department of Radiation Oncology, Richmond, Virginia., Sabo RT; Virginia Commonwealth University School of Medicine, Department of Biostatistics, Richmond, Virginia., Weaver KE; Wake Forest School of Medicine, Departments of Social Sciences and Health Policy & Implementation Science, Winston-Salem, North Carolina., Fuemmeler BF; Virginia Commonwealth University School of Medicine, Department of Health Behavior and Policy, Richmond, Virginia.
Publikováno v:
International journal of radiation oncology, biology, physics [Int J Radiat Oncol Biol Phys] 2023 May 01; Vol. 116 (1), pp. 28-38. Date of Electronic Publication: 2022 Jun 29.
Autor:
Burke A; Norwich Medical School, University of East Anglia, Norwich, Norfolk, UK., Jones A; Norwich Medical School, University of East Anglia, Norwich, Norfolk, UK., Hughes R; Active Norfolk, Easton Tennis Centre, Easton & Otley College, Norwich, UK., Player E; Norwich Medical School, University of East Anglia, Norwich, Norfolk, UK.
Publikováno v:
Dementia (London, England) [Dementia (London)] 2021 Jul; Vol. 20 (5), pp. 1604-1616. Date of Electronic Publication: 2020 Sep 05.
Autor:
Sebastian NT; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., Glenn C; Department of Radiation Oncology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, USA., Hughes R; Department of Radiation Oncology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, USA., Raval R; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., Chu J; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., DiCostanzo D; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., Bell EH; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., Grecula J; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., Arnett A; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., Gondal H; Department of Radiation Oncology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, USA., McGregor J; Department of Neurological Surgery, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., Elder JB; Department of Neurological Surgery, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., Lonser R; Department of Neurological Surgery, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., Chakravarti A; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA., Trifiletti D; Department of Radiation Oncology, Mayo Clinic, Jacksonville, USA., Brown PD; Department of Radiation Oncology, Mayo Clinic, Rochester, USA., Chan M; Department of Radiation Oncology, Wake Forest School of Medicine, Medical Center Boulevard, Winston-Salem, USA., Palmer JD; Department of Radiation Oncology, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA; Department of Neurological Surgery, The Ohio State University Comprehensive Cancer Center - Arthur G. James Cancer Hospital and Richard J. Solove Research Institute, Columbus, USA. Electronic address: Joshua.Palmer@osumc.edu.
Publikováno v:
Radiotherapy and oncology : journal of the European Society for Therapeutic Radiology and Oncology [Radiother Oncol] 2020 Jun; Vol. 147, pp. 136-143. Date of Electronic Publication: 2020 Mar 30.
Autor:
Jansen RS; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, NY, 10065, USA., Mandyoli L; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, 77843-2128, USA., Hughes R; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, 77843-2128, USA., Wakabayashi S; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, 02115, USA., Pinkham JT; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, 02115, USA., Selbach B; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, NY, 10065, USA., Guinn KM; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, 02115, USA., Rubin EJ; Department of Immunology and Infectious Diseases, Harvard T. H. Chan School of Public Health, Boston, MA, 02115, USA., Sacchettini JC; Department of Biochemistry and Biophysics, Texas A&M University, College Station, TX, 77843-2128, USA. sacchett@tamu.edu., Rhee KY; Division of Infectious Diseases, Department of Medicine, Weill Cornell Medical College, New York, NY, 10065, USA. kyr9001@med.cornell.edu.; Department of Microbiology & Immunology, Weill Cornell Medical College, New York, NY, 10065, USA. kyr9001@med.cornell.edu.
Publikováno v:
Nature communications [Nat Commun] 2020 Apr 23; Vol. 11 (1), pp. 1960. Date of Electronic Publication: 2020 Apr 23.
Autor:
Lanier CM; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC., Hughes R; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC., Ahmed T; Department of Medicine (Hematology & Oncology), Wake Forest School of Medicine, Winston-Salem, NC., LeCompte M; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC., Masters AH; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC., Petty WJ; Department of Medicine (Hematology & Oncology), Wake Forest School of Medicine, Winston-Salem, NC., Ruiz J; Department of Medicine (Hematology & Oncology), Wake Forest School of Medicine, Winston-Salem, NC.; W.G. (Bill) Hefner Veteran Administration Medical Center, Cancer Center, Salisbury, NC., Triozzi P; Department of Medicine (Hematology & Oncology), Wake Forest School of Medicine, Winston-Salem, NC., Su J; Department of Radiology, Wake Forest School of Medicine, Winston-Salem, NC., O'Neill S; Department of Pathology, Wake Forest School of Medicine, Winston-Salem, NC., Watabe K; Department of Cancer Biology, Wake Forest School of Medicine, Winston-Salem, NC., Cramer CK; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC., Laxton AW; Department of Neurosurgery, Wake Forest School of Medicine, Winston-Salem, NC., Tatter SB; Department of Neurosurgery, Wake Forest School of Medicine, Winston-Salem, NC., Wang G; Department of Biomedical Engineering, Rensselaer Polytechnic Institute, Troy, NY., Whitlow C; Department of Radiology, Wake Forest School of Medicine, Winston-Salem, NC., Chan MD; Department of Radiation Oncology, Wake Forest School of Medicine, Winston-Salem, NC.
Publikováno v:
Neuro-oncology practice [Neurooncol Pract] 2019 Sep; Vol. 6 (5), pp. 402-409. Date of Electronic Publication: 2019 Feb 05.