Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ryan R, Hosn"'
Autor:
Byungji, Kim, Ryan R, Hosn, Tanaka, Remba, Dongsoo, Yun, Na, Li, Wuhbet, Abraham, Mariane B, Melo, Manuel, Cortes, Bridget, Li, Yuebao, Zhang, Yizhou, Dong, Darrell J, Irvine
Publikováno v:
Journal of Controlled Release. 353:241-253
The recent clinical success of multiple mRNA-based SARS-CoV-2 vaccines has proven the potential of RNA formulated in lipid nanoparticles (LNPs) in humans, and products based on base-modified RNA, sequence-optimized RNA, and self-replicating RNAs form
Autor:
Ivan S. Pires, Kaiyuan Ni, Mariane Bandeira Melo, Na Li, Elana Ben-Akiva, Laura Maiorino, Jonathan Dye, Kristen A. Rodrigues, DongSoo Yun, Byungji Kim, Ryan R. Hosn, Paula T. Hammond, Darrell J. Irvine
Publikováno v:
Chemical Engineering Journal. 464:142664
Publikováno v:
Acta biomaterialia. 132
The majority of in vitro studies assessing cancer treatments are performed in two-dimensional (2D) monolayers and are subsequently validated in in vivo animal models. However, 2D models fail to accurately model the tumour microenvironment. Furthermor