Zobrazeno 1 - 10
of 176
pro vyhledávání: '"Ryan R, Brinkman"'
Autor:
David Martino, Nina Kresoje, Nelly Amenyogbe, Rym Ben-Othman, Bing Cai, Mandy Lo, Olubukola Idoko, Oludare A. Odumade, Reza Falsafi, Travis M. Blimkie, Andy An, Casey P. Shannon, Sebastiano Montante, Bhavjinder K. Dhillon, Joann Diray-Arce, Al Ozonoff, Kinga K. Smolen, Ryan R. Brinkman, Kerry McEnaney, Asimenia Angelidou, Peter Richmond, Scott J. Tebbutt, the EPIC-HIPC consortium, Beate Kampmann, Ofer Levy, Robert E. W. Hancock, Amy H. Y. Lee, Tobias R. Kollmann
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-14 (2024)
Abstract Understanding of newborn immune ontogeny in the first week of life will enable age-appropriate strategies for safeguarding vulnerable newborns against infectious diseases. Here we conducted an observational study exploring the immunological
Externí odkaz:
https://doaj.org/article/f8167ccffdeb4b0d9144c24cdeaf6fcb
Autor:
Xuehai Wang, Michael Nissen, Deanne Gracias, Manabu Kusakabe, Guillermo Simkin, Aixiang Jiang, Gerben Duns, Clementine Sarkozy, Laura Hilton, Elizabeth A. Chavez, Gabriela C. Segat, Rachel Wong, Jubin Kim, Tomohiro Aoki, Rashedul Islam, Christina May, Stacy Hung, Kate Tyshchenko, Ryan R. Brinkman, Martin Hirst, Aly Karsan, Ciara Freeman, Laurie H. Sehn, Ryan D. Morin, Andrew J. Roth, Kerry J. Savage, Jeffrey W. Craig, Sohrab P. Shah, Christian Steidl, David W. Scott, Andrew P. Weng
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-15 (2022)
Follicular lymphoma can transform to a more aggressive histology. Here, the authors use bulk and single cell analysis to create a 26 marker panel which could be used to profile FL samples and predict the risk of transformation using flow cytometry.
Externí odkaz:
https://doaj.org/article/d960f4dd0b9a426988ebdc70978507ff
Autor:
Amy H. Lee, Casey P. Shannon, Nelly Amenyogbe, Tue B. Bennike, Joann Diray-Arce, Olubukola T. Idoko, Erin E. Gill, Rym Ben-Othman, William S. Pomat, Simon D. van Haren, Kim-Anh Lê Cao, Momoudou Cox, Alansana Darboe, Reza Falsafi, Davide Ferrari, Daniel J. Harbeson, Daniel He, Cai Bing, Samuel J. Hinshaw, Jorjoh Ndure, Jainaba Njie-Jobe, Matthew A. Pettengill, Peter C. Richmond, Rebecca Ford, Gerard Saleu, Geraldine Masiria, John Paul Matlam, Wendy Kirarock, Elishia Roberts, Mehrnoush Malek, Guzmán Sanchez-Schmitz, Amrit Singh, Asimenia Angelidou, Kinga K. Smolen, The EPIC Consortium, Ryan R. Brinkman, Al Ozonoff, Robert E. W. Hancock, Anita H. J. van den Biggelaar, Hanno Steen, Scott J. Tebbutt, Beate Kampmann, Ofer Levy, Tobias R. Kollmann
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-14 (2019)
The first week of life impacts health for all of life, but the mechanisms are little-understood. Here the authors extract multi-omic data from small volumes of blood to study the dynamic molecular changes during the first week of life, revealing a ro
Externí odkaz:
https://doaj.org/article/e7ef77b9e7334ea3b111c65372e1f94f
Autor:
Casey P. Shannon, Travis M. Blimkie, Rym Ben-Othman, Nicole Gladish, Nelly Amenyogbe, Sibyl Drissler, Rachel D. Edgar, Queenie Chan, Mel Krajden, Leonard J. Foster, Michael S. Kobor, William W. Mohn, Ryan R. Brinkman, Kim-Anh Le Cao, Richard H. Scheuermann, Scott J. Tebbutt, Robert E.W. Hancock, Wayne C. Koff, Tobias R. Kollmann, Manish Sadarangani, Amy Huei-Yi Lee
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
BackgroundVaccination remains one of the most effective means of reducing the burden of infectious diseases globally. Improving our understanding of the molecular basis for effective vaccine response is of paramount importance if we are to ensure the
Externí odkaz:
https://doaj.org/article/2b50d5dc445d48949f659ab881399fe1
Autor:
Olubukola T. Idoko, Kinga K. Smolen, Oghenebrume Wariri, Abdulazeez Imam, Casey P. Shannon, Tida Dibassey, Joann Diray-Arce, Alansana Darboe, Julia Strandmark, Rym Ben-Othman, Oludare A. Odumade, Kerry McEnaney, Nelly Amenyogbe, William S. Pomat, Simon van Haren, Guzmán Sanchez-Schmitz, Ryan R. Brinkman, Hanno Steen, Robert E. W. Hancock, Scott J. Tebbutt, Peter C. Richmond, Anita H. J. van den Biggelaar, Tobias R. Kollmann, Ofer Levy, Al Ozonoff, Beate Kampmann
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Externí odkaz:
https://doaj.org/article/564600662ed146e48c43dbd0a6193f94
Autor:
Rym Ben-Othman, Bing Cai, Aaron C. Liu, Natallia Varankovich, Daniel He, Travis M. Blimkie, Amy H. Lee, Erin E. Gill, Mark Novotny, Brian Aevermann, Sibyl Drissler, Casey P. Shannon, Sarah McCann, Kim Marty, Gordean Bjornson, Rachel D. Edgar, David Tse Shen Lin, Nicole Gladish, Julia Maclsaac, Nelly Amenyogbe, Queenie Chan, Alba Llibre, Joyce Collin, Elise Landais, Khoa Le, Samantha M. Reiss, Wayne C. Koff, Colin Havenar-Daughton, Manraj Heran, Bippan Sangha, David Walt, Mel Krajden, Shane Crotty, Devin Sok, Bryan Briney, Dennis R. Burton, Darragh Duffy, Leonard J. Foster, William W. Mohn, Michael S. Kobor, Scott J. Tebbutt, Ryan R. Brinkman, Richard H. Scheuermann, Robert E. W. Hancock, Tobias R. Kollmann, Manish Sadarangani
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
Conventional vaccine design has been based on trial-and-error approaches, which have been generally successful. However, there have been some major failures in vaccine development and we still do not have highly effective licensed vaccines for tuberc
Externí odkaz:
https://doaj.org/article/161a4130886644838de4892cc5710d1d
Autor:
Geoff D. E. Cuvelier, Amanda Li, Sibyl Drissler, Amina Kariminia, Sayeh Abdossamadi, Jacob Rozmus, Jean-Pierre Chanoine, Bernard Ng, Sara Mostafavi, Ryan R. Brinkman, Kirk R. Schultz
Publikováno v:
Frontiers in Immunology, Vol 11 (2020)
It is established that pediatric hematopoietic stem cell transplant (HSCT) recipients have a lower rate of chronic graft-versus-host disease (cGvHD) compared to adults. Our group has previously published immune profiles changes associated with cGvHD
Externí odkaz:
https://doaj.org/article/4830d325e8de432cb647a864796d1c36
Autor:
Olubukola T. Idoko, Kinga K. Smolen, Oghenebrume Wariri, Abdulazeez Imam, Casey P. Shannon, Tida Dibassey, Joann Diray-Arce, Alansana Darboe, Julia Strandmark, Rym Ben-Othman, Oludare A. Odumade, Kerry McEnaney, Nelly Amenyogbe, William S. Pomat, Simon van Haren, Guzmán Sanchez-Schmitz, Ryan R. Brinkman, Hanno Steen, Robert E. W. Hancock, Scott J. Tebbutt, Peter C. Richmond, Anita H. J. van den Biggelaar, Tobias R. Kollmann, Ofer Levy, Al Ozonoff, Beate Kampmann
Publikováno v:
Frontiers in Pediatrics, Vol 8 (2020)
Background: Infection contributes to significant morbidity and mortality particularly in the very young and in low- and middle-income countries. While vaccines are a highly cost-effective tool against infectious disease little is known regarding the
Externí odkaz:
https://doaj.org/article/52c3e0f20b92408f90c7e9ad693c486c
Autor:
Katharina Rothe, Artem Babaian, Keith Keith Humphries, Jonathan Zeng, Xiaoyan Jiang, Min Chen, Donna L. Forrest, Hanyang Lin, Oleh Petriv, Inanc Birol, Connie J. Eaves, Jens Ruschmann, Tobias Maetzig, Ryan R. Brinkman, David J.H.F. Knapp, Naoto Nakamichi, Kieran O'Neill, Carl L. Hansen, Ryan Yen, Andrew Wu
Publikováno v:
Blood
Overcoming drug resistance and targeting cancer stem cells remain challenges for curative cancer treatment. To investigate the role of microRNAs (miRNAs) in regulating drug resistance and leukemic stem cell (LSC) fate, we performed global transcripto
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::244fcbe5e7d9ca676c08de606117ab56
https://doi.org/10.1182/blood.2019003636
https://doi.org/10.1182/blood.2019003636
Autor:
Hideki Nakano, Alexander V. Misharin, William J. Zacharias, Susanne Herold, Suchitra Swaminathan, Benjamin D. Singer, Elizabeth F. Redente, Claudia Jakubzick, Ryan Duggan, William J. Janssen, Anne I. Sperling, Christine M. Freeman, Jeffrey L. Curtis, Ryan R. Brinkman, Robert M. Tighe, Yen-Rei A. Yu
Publikováno v:
American Journal of Respiratory Cell and Molecular Biology
Defining responses of the structural and immune cells in biologic systems is critically important to understanding disease states and responses to injury. This requires accurate and sensitive methods to define cell types in organ systems. The princip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52320b34bddc75864ad9e4d194a46e84
http://europepmc.org/articles/PMC6670040
http://europepmc.org/articles/PMC6670040