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pro vyhledávání: '"Ryan Posgai"'
Publikováno v:
Mutagenesis
In vitro genotoxicity assays utilising human skin models are becoming important tools for the safety assessment of chemicals whose primary exposure is via the dermal route. In order to explore metabolic competency and inducibility of CYP450 activatin
Autor:
Mark G. Nielsen, Saber M. Hussain, John J. Rowe, Kyle Robert Murphy, Ryan Posgai, Caitlin B. Cipolla-McCulloch
Publikováno v:
Chemosphere. 85:34-42
Silver and titanium dioxide nanoparticles are known to induce oxidative stress in vitro and in vivo. Here we test if they impact development, mating success, and survivorship in Drosophila melanogaster, and if so, if these effects are reversible by a
Autor:
John J. Rowe, Ryan Posgai, Mark G. Nielsen, Timothy J. Gorey, Maqusood Ahamed, Saber M. Hussain
Publikováno v:
Toxicology and applied pharmacology. 242(3)
Due to the intensive commercial application of silver nanoparticles (Ag NPs), risk assessment of this nanoparticle is of great importance. Our previous in vitro study demonstrated that Ag NPs caused DNA damage and apoptosis in mouse embryonic stem ce