Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ryan P. Manuszak"'
Autor:
Rodney E. Shackelford, Torrie C. Brooks, Suming Wang, Mary Lowery-Nordberg, Yumei Fu, Adrian Sequeira, Ryan P. Manuszak, Anping Chen
Publikováno v:
DNA Repair. 5:1327-1336
Ataxia-telangiectasia (A-T) is characterized by ataxia, genomic instability, and increased cancer incidence. Previously, iron chelator concentrations which suppressed normal cell colony formation increased A-T cell colony formation. Similarly, iron c
Autor:
Suming Wang, Rodney E. Shackelford, Charles J. Link, Cybele D. Johnson, Daniel J. Hellrung, Ryan P. Manuszak
Publikováno v:
DNA Repair. 3:1263-1272
Ataxia telangeictasia (A-T) is an autosomal recessive disorder characterized by immune dysfunction, genomic instability, chronic oxidative damage, and increased cancer incidence. Previously, desferal was found to increase the resistance of A-T, but n
Autor:
Daniel J. Hellrung, Rodney Edwin Shackelford, Cybele D. Johnson, Timothy A. Steele, Charles J. Link, Suming Wang, Ryan P. Manuszak
Publikováno v:
DNA Repair. 2:971-981
Ataxia-telangiectasia (AT) is an autosomal recessive disorder characterized by genomic instability, chronic oxidative damage, and increased cancer incidence. Compared to normal cells, AT cells exhibit unusual sensitivity to exogenous oxidants, includ
Publikováno v:
Medical hypotheses. 64(4)
Parkinson's disease (PD) is a major cause of morbidity and mortality among older individuals. Although the causes of Parkinson's disease are multifactorial, considerable evidence indicates that elevated labile iron in the substantia nigra pars compac
Publikováno v:
Molecular Therapy. 9:S203
Ataxia-telangiectasia (A-T) is a progressive degenerative autosomal recessive disease characterized by ataxia, telangiectases, immune dysfunction, cancer predisposition, and sensitivity to ionzing radiation. Presently, there is no treatment to slow t