Zobrazeno 1 - 10
of 28
pro vyhledávání: '"Ryan P. Kelley"'
Autor:
Karim Johari, Ryan M. Kelley, Kris Tjaden, Charity G. Patterson, Andrea H. Rohl, Joel I. Berger, Daniel M. Corcos, Jeremy D. W. Greenlee
Publikováno v:
Frontiers in Human Neuroscience, Vol 17 (2023)
Deep brain stimulation (DBS) of the subthalamic nucleus (STN), which consistently improves limb motor functions, shows mixed effects on speech functions in Parkinson’s disease (PD). One possible explanation for this discrepancy is that STN neurons
Externí odkaz:
https://doaj.org/article/6dd071880cb9483cbb9513fa0befb4c9
Autor:
Florian Regent, Zachary Batz, Ryan A. Kelley, Linn Gieser, Anand Swaroop, Holly Y. Chen, Tiansen Li
Publikováno v:
Frontiers in Cellular Neuroscience, Vol 16 (2022)
Retinal organoids (ROs) derived from human pluripotent stem cells (hPSCs) recapitulate key features of retinogenesis and provide a promising platform to study retinal development and disease in a human context. Although multiple protocols are current
Externí odkaz:
https://doaj.org/article/19a7abd63dc04d12b484009ffea433a9
Autor:
Matthew J. Brooks, Holly Y. Chen, Ryan A. Kelley, Anupam K. Mondal, Kunio Nagashima, Natalia De Val, Tiansen Li, Vijender Chaitankar, Anand Swaroop
Publikováno v:
Stem Cell Reports, Vol 13, Iss 5, Pp 891-905 (2019)
Summary: Stem cell-derived retinal organoids recapitulate many landmarks of in vivo differentiation but lack functional maturation of distinct cell types, especially photoreceptors. Using comprehensive temporal transcriptome analyses, we show that tr
Externí odkaz:
https://doaj.org/article/55d75f04bc144eb088aab1172e9f26fa
Publikováno v:
STAR Protocols, Vol 1, Iss 1, Pp 100018- (2020)
Summary: Mouse pluripotent stem cells can be efficiently differentiated into retinal organoids with polarized, laminated neural retina harboring all retinal cell types by the Hypoxia-Induced Generation of Photoreceptor in Retinal Organoids (HIPRO) pr
Externí odkaz:
https://doaj.org/article/41dfe311da7845528f3a1b8836cd333d
Publikováno v:
STAR Protocols, Vol 1, Iss 1, Pp 100033- (2020)
Summary: Human pluripotent stem cells (PSCs) can be differentiated into retinal organoids with proper neural layer organization, yet the protocols are technically challenging and time consuming. We have modified a widely used differentiation protocol
Externí odkaz:
https://doaj.org/article/b9c5825780fa4cf4aada6f671109df36
Autor:
Eric B Emmons, Rafael Naime Ruggiero, Ryan M Kelley, Krystal Lynn Parker, Nandakumar eNarayanan
Publikováno v:
Frontiers in Psychology, Vol 7 (2016)
Organizing movements in time is a critical and highly conserved feature of mammalian behavior. Temporal control of action requires corticostriatal networks. We investigate these networks in rodents using a two-interval timing task while recording loc
Externí odkaz:
https://doaj.org/article/030d22f14689427a8b289110e7aef26a
Autor:
Madhoosudan A. Patil, Brock A. Matter, Yogendra H. Raol, David W. A. Bourne, Ryan A. Kelley, Uday B. Kompella
Publikováno v:
Pharmaceutics, Vol 10, Iss 4, p 281 (2018)
Flupirtine, a nonopioid analgesic drug, is effective in treating neonatal seizures. However, its brain delivery and pharmacokinetics are unknown in neonatal mammals. The purpose of this study was to determine the pharmacokinetics of flupirtine and th
Externí odkaz:
https://doaj.org/article/70f65b48e3a043f38c71786e67e4956e
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 830:44-52
Three algorithms were investigated for discriminating between neutrons and gamma rays in a pressurized 4 He gas fast neutron detector: charge comparison, weighted integration, and neutron-gamma model analysis (NGMA). For each algorithm, a comprehensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::869eac0d2d2f5a87eb4e2b5b2d81178f
https://doi.org/10.1016/j.nima.2016.05.065
https://doi.org/10.1016/j.nima.2016.05.065
Autor:
Thomas N. Massey, Andreas Enqvist, Ryan P. Kelley, D. Murer, Lucas M. Rolison, Jason M. Lewis, Kelly A. Jordan
Publikováno v:
Nuclear Instruments and Methods in Physics Research Section A: Accelerators, Spectrometers, Detectors and Associated Equipment. 793:101-107
Time-of-flight measurements were conducted to characterize the neutron energy response of pressurized 4He fast neutron scintillation detectors for the first time, using the Van de Graaff generator at Ohio University. The time-of-flight spectra and pu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::05fd50504e7d546c58d101693edc442c
https://doi.org/10.1016/j.nima.2015.04.011
https://doi.org/10.1016/j.nima.2015.04.011
Publikováno v:
Annals of Nuclear Energy. 80:460-466
An uncertainty analysis of non-destructive assay of spent fuel using a delayed neutron method was conducted to explicitly define the accuracy with which plutonium content in an uncharacterized sample can be assessed. Perturbing various parameters all
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f730b3c305eee0d9c7afd08bc418e384
https://doi.org/10.1016/j.anucene.2015.02.037
https://doi.org/10.1016/j.anucene.2015.02.037