Zobrazeno 1 - 10
of 24
pro vyhledávání: '"Ryan P. Gilley"'
Autor:
Norberto Gonzalez-Juarbe, Ashleigh N. Riegler, Alexander S. Jureka, Ryan P. Gilley, Jeffrey D. Brand, John E. Trombley, Ninecia R. Scott, Maryann P. Platt, Peter H. Dube, Chad M. Petit, Kevin S. Harrod, Carlos J. Orihuela
Publikováno v:
Cell Reports, Vol 32, Iss 8, Pp 108062- (2020)
Summary: Pneumonias caused by influenza A virus (IAV) co- and secondary bacterial infections are characterized by their severity and high mortality rate. Previously, we have shown that bacterial pore-forming toxin (PFT)-mediated necroptosis is a key
Externí odkaz:
https://doaj.org/article/b804d5f73aa147ecb872b34cc558199e
Autor:
Anukul T Shenoy, Terry Brissac, Ryan P Gilley, Nikhil Kumar, Yong Wang, Norberto Gonzalez-Juarbe, Whitney S Hinkle, Sean C Daugherty, Amol C Shetty, Sandra Ott, Luke J Tallon, Jessy Deshane, Hervé Tettelin, Carlos J Orihuela
Publikováno v:
PLoS Pathogens, Vol 13, Iss 8, p e1006582 (2017)
For over 130 years, invasive pneumococcal disease has been associated with the presence of extracellular planktonic pneumococci, i.e. diplococci or short chains in affected tissues. Herein, we show that Streptococcus pneumoniae that invade the myocar
Externí odkaz:
https://doaj.org/article/ab3eee1c889049c0b3060857d0f4005e
Autor:
Ryan P. Gilley, Yanbao Yu, David M. Brown, Peter H. Dube, Norberto Gonzalez-Juarbe, Maryann P. Platt, Yi-Han Lin
Publikováno v:
Circ Res
Rationale: Patients with and without cardiovascular diseases have been shown to be at risk of influenza-mediated cardiac complications. Recent clinical reports support the notion of a direct link between laboratory-confirmed influenza virus infection
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::85dd2a5a3ed6576bfa7e3eb0af7eab0d
https://doi.org/10.1161/circresaha.120.318511
https://doi.org/10.1161/circresaha.120.318511
Autor:
Luis F Reyes, Marcos I Restrepo, Cecilia A Hinojosa, Nilam J Soni, Anukul T Shenoy, Ryan P Gilley, Norberto Gonzalez-Juarbe, Julio R Noda, Vicki T Winter, Melissa A de la Garza, Robert E Shade, Jacqueline J Coalson, Luis D Giavedoni, Antonio Anzueto, Carlos J Orihuela
Publikováno v:
PLoS ONE, Vol 11, Iss 11, p e0166092 (2016)
RATIONALE:Streptococcus pneumoniae is the leading cause of community-acquired pneumonia and infectious death in adults worldwide. A non-human primate model is needed to study the molecular mechanisms that underlie the development of severe pneumonia,
Externí odkaz:
https://doaj.org/article/b37a6465e5f543778679681819181fb9
Autor:
Ryan P. Gilley, Peter H. Dube
Publikováno v:
Oncotarget. 11:740-754
Melanoma continues to be a significant health concern worldwide despite recent improvements in treatment. Unlike many other prominent cancers, melanoma incidence in both men and women increased over the past decade in the U. S. and much of the develo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::37eee08234abef0424cf6ed13987a9f4
https://doi.org/10.18632/oncotarget.27490
https://doi.org/10.18632/oncotarget.27490
Publikováno v:
Microb Pathog
Environmental allergens elicit complex immune responses in the lungs that can promote the development of asthma or exacerbate preexisting asthma in susceptible individuals. House dust mites are one of the most common indoor allergens and are a signif
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::35b7b8eaf89b0e351fbaab11074d9275
https://doi.org/10.1016/j.micpath.2019.02.019
https://doi.org/10.1016/j.micpath.2019.02.019
Autor:
Peter H. Dube, Ryan P. Gilley
Publikováno v:
Am J Public Health
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::3348d72849049357d88f2726ea142006
https://pubmed.ncbi.nlm.nih.gov/32639917
https://pubmed.ncbi.nlm.nih.gov/32639917
Autor:
Katherine L Kruckow, Ashleigh N. Riegler, Sarah M. Beno, Yong Wang, Marcos I. Restrepo, Ryan P. Gilley, Anukul T. Shenoy, Griffin M. Wright, Norberto Gonzalez-Juarbe, Sara N Stoner, Jeevan Kumar Jadapalli, Ganesh V. Halade, Jessy S. Deshane, Carlos J. Orihuela, Terry Brissac
Publikováno v:
J Infect Dis
Background Streptococcus pneumoniae infection can result in bacteremia with devastating consequences including heart damage. Necroptosis is a proinflammatory form of cell death instigated by pore-forming toxins such as S. pneumoniae pneumolysin. Necr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::00ab9583684ef6e6a936fe439db2ee0c
https://europepmc.org/articles/PMC7896277/
https://europepmc.org/articles/PMC7896277/
Autor:
Alexander S. Jureka, Peter H. Dube, Ryan P. Gilley, Norberto Gonzalez-Juarbe, Ninecia R. Scott, Jeffrey D. Brand, Chad M. Petit, Kevin S. Harrod, Ashleigh N. Riegler, John E. Trombley, Carlos J. Orihuela
RationalePneumonia caused by Influenza A virus (IAV) co- and secondary bacterial infections are characterized by their severity. Previously we have shown that pore-forming toxin (PFT)-mediated necroptosis is a key driver of acute lung injury during b
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::635f214de8d633b00d4f71705ae6f9c5
Autor:
Carlos J. Orihuela, Luis F. Reyes, Anukul T. Shenoy, Kelley M. Bradley, Ryan P. Gilley, Peter H. Dube, Marcos I. Restrepo, Cecilia A. Hinojosa, Norberto Gonzalez-Juarbe, Molly A. Bergman
Publikováno v:
Cell Death & Differentiation. 24:917-928
We report that pore-forming toxins (PFTs) induce respiratory epithelial cell necroptosis independently of death receptor signaling during bacterial pneumonia. Instead, necroptosis was activated as a result of ion dysregulation arising from membrane p
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d0f2dcf8ca52c26553ace5771ad0c96b
https://doi.org/10.1038/cdd.2017.49
https://doi.org/10.1038/cdd.2017.49