Zobrazeno 1 - 10
of 17
pro vyhledávání: '"Ryan P Donahue"'
Autor:
Margaret E. Maes, Ryan J. Donahue, Cassandra L. Schlamp, Olivia J. Marola, Richard T. Libby, Robert W. Nickells
Publikováno v:
Molecular Neurodegeneration, Vol 18, Iss 1, Pp 1-22 (2023)
Abstract Background Pro-apoptotic BAX is a central mediator of retinal ganglion cell (RGC) death after optic nerve damage. BAX activation occurs in two stages including translocation of latent BAX to the mitochondrial outer membrane (MOM) and then pe
Externí odkaz:
https://doaj.org/article/7657e4fe09f54146a892dfbcaf469f51
Autor:
Benjamin J. Bielajew, Ryan P. Donahue, Elliott K. Lamkin, Jerry C. Hu, Vincent C. Hascall, Kyriacos A. Athanasiou
Publikováno v:
Biomaterials Research, Vol 26, Iss 1, Pp 1-14 (2022)
Abstract Background The self-assembling process of cartilage tissue engineering is a promising technique to heal cartilage defects, preventing osteoarthritic changes. Given that chondrocytes dedifferentiate when expanded, it is not known if cellular
Externí odkaz:
https://doaj.org/article/be08122a2db343e28e3466bcd3ec49d6
Publikováno v:
Cell Death and Disease, Vol 12, Iss 8, Pp 1-11 (2021)
Abstract Axonal degeneration of retinal ganglion cells (RGCs) causes blindness in glaucoma. Currently, there are no therapies that target axons to prevent them from degenerating. Activation of the BAX protein has been shown to be the determining step
Externí odkaz:
https://doaj.org/article/680aac1197894499b42cbfae53274c72
Autor:
Benjamin J. Bielajew, Ryan P. Donahue, M. Gabriela Espinosa, Boaz Arzi, Dean Wang, David C. Hatcher, Nikolaos K. Paschos, Mark E.K. Wong, Jerry C. Hu, Kyriacos A. Athanasiou
Publikováno v:
Cell Reports Medicine, Vol 2, Iss 5, Pp 100241- (2021)
Summary: Although the knee joint and temporomandibular joint (TMJ) experience similar incidence of cartilage ailments, the knee orthopedics field has greater funding and more effective end-stage treatment options. Translational research has resulted
Externí odkaz:
https://doaj.org/article/a9cf1ed5d4e3423aab2048a914cb8b4c
Autor:
Nicole A. Muench, Sonia Patel, Margaret E. Maes, Ryan J. Donahue, Akihiro Ikeda, Robert W. Nickells
Publikováno v:
Cells, Vol 10, Iss 7, p 1593 (2021)
The important roles of mitochondrial function and dysfunction in the process of neurodegeneration are widely acknowledged. Retinal ganglion cells (RGCs) appear to be a highly vulnerable neuronal cell type in the central nervous system with respect to
Externí odkaz:
https://doaj.org/article/881a629da11c4c40a617383655be56e0
The Effect of Neonatal, Juvenile, and Adult Donors on Rejuvenated Neocartilage Functional Properties
Autor:
Kyriacos A. Athanasiou, Benjamin J. Bielajew, Ryan P. Donahue, Rachel C. Nordberg, Jerry C. Hu
Publikováno v:
Tissue Eng Part A
Tissue engineering. Part A, vol 28, iss 9-10
Tissue engineering. Part A, vol 28, iss 9-10
Cartilage does not naturally heal, and cartilage lesions from trauma and wear-and-tear can lead to eventual osteoarthritis. To address long-term repair, tissue engineering of functional biologic implants to treat cartilage lesions is desirable, but t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::08125217dc3ab650bd8a87d661a10ca2
https://pubmed.ncbi.nlm.nih.gov/34605665
https://pubmed.ncbi.nlm.nih.gov/34605665
Publikováno v:
Tissue Engineering Part A.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::7c4bdf0856a6f5620fa7a6a02218957c
https://doi.org/10.1089/ten.tea.2023.0011
https://doi.org/10.1089/ten.tea.2023.0011
Publikováno v:
The Canadian journal of urology. 29(3)
A 71-year-old woman with history of asthma presented with 2 months history of shortness of breath; on imaging an incidental left renal mass was noted. Subsequent renal protocol CT was obtained that showed a 4.5 cm left upper pole exophytic mass with
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::21c408d8e77b6e4ca40ac2b26a9f768e
https://pubmed.ncbi.nlm.nih.gov/35691042
https://pubmed.ncbi.nlm.nih.gov/35691042
Autor:
Jarrett M. Link, Kyriacos A. Athanasiou, Jerry C. Hu, Wendy Liu, Vijaykumar S. Meli, Ryan P. Donahue
Publikováno v:
Biomater Sci
Biomaterials science, vol 9, iss 23
Biomaterials science, vol 9, iss 23
Evaluating the host immune response to biomaterials is an essential step in the development of medical devices and tissue engineering strategies. To aid in this process, in vitro studies, whereby immune cells such as macrophages are cultured on bioma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::73041a01df3c2e83503d842ac34095d4
https://doi.org/10.1039/d1bm00746g
https://doi.org/10.1039/d1bm00746g
Autor:
Benjamin J. Bielajew, Ryan P. Donahue, Elliott K. Lamkin, Jerry C. Hu, Vincent C. Hascall, Kyriacos A. Athanasiou
Publikováno v:
Acta Biomater
The objective of this work is to examine the development of porcine cartilage by analyzing its mechanical properties, biochemical content, and proteomics at different developmental stages. Cartilage from the knees of fetal, neonatal, juvenile, and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d085817916ef15ad8414e0d81676f8c5
https://escholarship.org/uc/item/05b0s5dt
https://escholarship.org/uc/item/05b0s5dt
