Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Ryan P Cassidy"'
Autor:
Erik G Puffenberger, Robert N Jinks, Carrie Sougnez, Kristian Cibulskis, Rebecca A Willert, Nathan P Achilly, Ryan P Cassidy, Christopher J Fiorentini, Kory F Heiken, Johnny J Lawrence, Molly H Mahoney, Christopher J Miller, Devika T Nair, Kristin A Politi, Kimberly N Worcester, Roni A Setton, Rosa Dipiazza, Eric A Sherman, James T Eastman, Christopher Francklyn, Susan Robey-Bond, Nicholas L Rider, Stacey Gabriel, D Holmes Morton, Kevin A Strauss
Publikováno v:
PLoS ONE, Vol 7, Iss 1, p e28936 (2012)
The Clinic for Special Children (CSC) has integrated biochemical and molecular methods into a rural pediatric practice serving Old Order Amish and Mennonite (Plain) children. Among the Plain people, we have used single nucleotide polymorphism (SNP) m
Externí odkaz:
https://doaj.org/article/7c28aa674b674c77b7d6bd3569aa9184
Autor:
Thyago Antonelli-Salgado, Luis Francisco Ramos-Lima, Cristiane dos Santos Machado, Ryan Michael Cassidy, Taiane de Azevedo Cardoso, Flávio Kapczinski, Ives Cavalcante Passos
Publikováno v:
Trends in Psychiatry and Psychotherapy, Vol 43, Iss 3, Pp 167-176 (2021)
Abstract Introduction Neuroprogression has been proposed as the pathological rewiring of the brain that takes place in parallel with clinical and neurocognitive deterioration in the course of psychiatric disorders. This study aims to review the biolo
Externí odkaz:
https://doaj.org/article/78c0263ba7184395b29c7970b4765574
Publikováno v:
Scientific Reports, Vol 11, Iss 1, Pp 1-14 (2021)
Abstract Brain-derived neurotrophic factor (BDNF) is critically involved in the pathophysiology of chronic pain. However, the mechanisms of BDNF action on specific neuronal populations in the spinal superficial dorsal horn (SDH) requires further stud
Externí odkaz:
https://doaj.org/article/3e69283edd694e9888f90e726ca6e55a
Autor:
Eun Ran Kim, Yuanzhong Xu, Ryan M. Cassidy, Yungang Lu, Yongjie Yang, Jinbin Tian, De-Pei Li, Rachel Van Drunen, Aleix Ribas-Latre, Zhao-Lin Cai, Mingshan Xue, Benjamin R. Arenkiel, Kristin Eckel-Mahan, Yong Xu, Qingchun Tong
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-17 (2020)
Defective rhythmic metabolism is associated with high-fat diet feeding and obesity. The authors show that the clock gene BMAL1 drives paraventricular hypothalamic neuron activity via rhythmic GABAergic neurotransmission, and that this mediates diurna
Externí odkaz:
https://doaj.org/article/b479012e40434818870fa48db8ae759a
Autor:
Yuanzhong Xu, Yungang Lu, Ryan M. Cassidy, Leandra R. Mangieri, Canjun Zhu, Xugen Huang, Zhiying Jiang, Nicholas J. Justice, Yong Xu, Benjamin R. Arenkiel, Qingchun Tong
Publikováno v:
Nature Communications, Vol 10, Iss 1, Pp 1-16 (2019)
Eating disorders are often comorbid with emotional and psychiatric symptoms yet the underlying neural circuits are poorly understood. Here, the authors report that projections from the paraventricular hypothalamus to the ventral part of the lateral s
Externí odkaz:
https://doaj.org/article/0c2fcdba000446b7b2c235b93aa094a9
Autor:
Leandra R. Mangieri, Yungang Lu, Yuanzhong Xu, Ryan M. Cassidy, Yong Xu, Benjamin R. Arenkiel, Qingchun Tong
Publikováno v:
Nature Communications, Vol 9, Iss 1, Pp 1-15 (2018)
Feeding disorders are often comorbid with compulsive behaviours but the underlying neural circuits are not known. Here the authors demonstrate that glutamatergic and GABAergic projections from the LH to the PVH exert antagonistic effects on grooming
Externí odkaz:
https://doaj.org/article/53541804e2c140519745f50b0fe25934
Publikováno v:
Journal of Clinical and Translational Science, Vol 1, Pp 1-2 (2017)
OBJECTIVES/SPECIFIC AIMS: To demonstrate that olanzapine recapitulates the effect of increased lateral hypothalamic (LH) GABAergic activity in the DRN and the DBB. This will provide a potential neural substrate for the observed increase in consumptio
Externí odkaz:
https://doaj.org/article/8355301e354647279afa98619f6ca545
Autor:
Ryan Michael Cassidy, Qingchun Tong
Publikováno v:
Frontiers in Endocrinology, Vol 8 (2017)
Many of the neurocircuits and hormones known to underlie the sensations of hunger and satiety also substantially alter the activity of the dopaminergic reward system. Much interest lies in the ways that hunger, satiety, and reward tie together, as th
Externí odkaz:
https://doaj.org/article/f13f0e6fb2af485ba7f39c856601be7e
Autor:
Haiyan Li, Xinni Luo, Xiaoyin Ke, Qing Dai, Wei Zheng, Chanjuan Zhang, Ryan M Cassidy, Jair C Soares, XiangYang Zhang, Yuping Ning
Publikováno v:
PLoS ONE, Vol 12, Iss 10, p e0186143 (2017)
Somatic complaints are often the presenting symptoms of major depressive disorder (MDD) in the outpatient context, because this may go unrecognized. It is well understood that MDD carries an increased risk of suicide. This study aimed to identify the
Externí odkaz:
https://doaj.org/article/f08ea1a7d92c4a7aa7e56f202c55aa5a