Zobrazeno 1 - 10
of 75
pro vyhledávání: '"Ryan P, McMillan"'
Autor:
Razan M. Alajoleen, David N. Oakland, Rana Estaleen, Aida Shakeri, Ran Lu, Michael Appiah, Sha Sun, Jonathan Neumann, Shimako Kawauchi, Thomas E. Cecere, Ryan P. McMillan, Christopher M. Reilly, Xin M. Luo
Publikováno v:
Frontiers in Immunology, Vol 15 (2024)
IntroductionLeaky gut has been linked to autoimmune disorders including lupus. We previously reported upregulation of anti-flagellin antibodies in the blood of lupus patients and lupus-prone mice, which led to our hypothesis that a leaky gut drives l
Externí odkaz:
https://doaj.org/article/e0ef88a8a34d4fdc9a82a8111be4317d
Autor:
Elizabeth N. Kaweesa, Abinash Padhi, Grace N. Davis, Ryan P. McMillan, David A. Brown, Amrinder S. Nain, Sandra Loesgen
Publikováno v:
Advances in Cancer Biology - Metastasis, Vol 6, Iss , Pp 100070- (2022)
Melanoma is the most prevalent and aggressive form of skin cancer, often with a low survival rate due to rapid metastasis and a high occurrence of multi-drug resistance (MDR). In this study, we examine the combination treatment of the recently discov
Externí odkaz:
https://doaj.org/article/a198ff1adecc4408b55de9378415d449
Autor:
Shelby E. Hamm, Daniel D. Fathalikhani, Katherine E. Bukovec, Adele K. Addington, Haiyan Zhang, Justin B. Perry, Ryan P. McMillan, Michael W. Lawlor, Mariah J. Prom, Mark A. Vanden Avond, Suresh N. Kumar, Kirsten E. Coleman, J.B. Dupont, David L. Mack, David A. Brown, Carl A. Morris, J. Patrick Gonzalez, Robert W. Grange
Publikováno v:
Molecular Therapy: Methods & Clinical Development, Vol 21, Iss , Pp 144-160 (2021)
We tested the hypothesis that voluntary wheel running would complement microdystrophin gene therapy to improve muscle function in young mdx mice, a model of Duchenne muscular dystrophy. mdx mice injected with a single dose of AAV9-CK8-microdystrophin
Externí odkaz:
https://doaj.org/article/d1cbb7f0e57f48a4854b84e1f8896a3a
Autor:
Kalyn S. Specht, Shashi Kant, Adele K. Addington, Ryan P. McMillan, Matthew W. Hulver, Heather Learnard, Maura Campbell, Sarah R. Donnelly, Amada D. Caliz, Yongmei Pei, Michaella M. Reif, Jacob M. Bond, Anthony DeMarco, Branch Craige, John F. Keaney, Jr., Siobhan M. Craige
Publikováno v:
Molecular Metabolism, Vol 45, Iss , Pp 101160- (2021)
Objective: The immediate signals that couple exercise to metabolic adaptations are incompletely understood. Nicotinamide adenine dinucleotide phosphate oxidase 4 (Nox4) produces reactive oxygen species (ROS) and plays a significant role in metabolic
Externí odkaz:
https://doaj.org/article/42e8a6b1e9fb448a8d2777118c18bc64
Autor:
Michael D. Tarpey, Kevin P. Davy, Ryan P. McMillan, Suzanne M. Bowser, Tanya M. Halliday, Nabil E. Boutagy, Brenda M. Davy, Madlyn I. Frisard, Matthew W. Hulver
Publikováno v:
Molecular Metabolism, Vol 6, Iss 12, Pp 1597-1609 (2017)
Objective: We tested the hypothesis that skeletal muscle of endurance-trained male runners would exhibit elevated autophagy and mitophagy markers, which would be associated with greater metabolic flexibility following a high-fat meal (HFM). Methods:
Externí odkaz:
https://doaj.org/article/d5c9eb071ba148c0b2c947732f17130d
Autor:
Jingjing Ren, Michelle D. Catalina, Kristin Eden, Xiaofeng Liao, Kaitlin A. Read, Xin Luo, Ryan P. McMillan, Matthew W. Hulver, Matthew Jarpe, Prathyusha Bachali, Amrie C. Grammer, Peter E. Lipsky, Christopher M. Reilly
Publikováno v:
Frontiers in Immunology, Vol 10 (2019)
Autoantibody production by plasma cells (PCs) plays a pivotal role in the pathogenesis of systemic lupus erythematosus (SLE). The molecular pathways by which B cells become pathogenic PC secreting autoantibodies in SLE are incompletely characterized.
Externí odkaz:
https://doaj.org/article/912a3f150eb740fdb3086057c5f2a8a7
Autor:
Dane W. Fausnacht, Kellie A. Kroscher, Ryan P. McMillan, Luciane S. Martello, Lance H. Baumgard, Joshua T. Selsby, Matthew W. Hulver, Robert P. Rhoads
Publikováno v:
Animals, Vol 11, Iss 1, p 215 (2021)
Heat stress (HS) diminishes animal production, reducing muscle growth and increasing adiposity, especially in swine. Excess heat creates a metabolic phenotype with limited lipid oxidation that relies on aerobic and anaerobic glycolysis as a predomina
Externí odkaz:
https://doaj.org/article/52ec8de15b7f4400a85bb34482a38ca8
Autor:
Melanie Lancaster, Matthew W. Hulver, Michelle S Rockwell, D. Enette Larson-Meyer, Ryan P. McMillan, Samantha B. Kostelnik
Publikováno v:
Medicine & Science in Sports & Exercise. 54:371-376
INTRODUCTION Although vitamin D is intimately involved in bone metabolism, the relationship between vitamin D status, as measured by serum total 25-hydroxyvitamin D [25(OH)D] concentration, and bone mineral density (BMD) is weak, particularly in non-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::af7f56b7829f25bf391225ee80cc5249
https://doi.org/10.1249/mss.0000000000002807
https://doi.org/10.1249/mss.0000000000002807
Autor:
Su Gao, Ryan P. McMillan, Qingzhang Zhu, Gary D. Lopaschuk, Matthew W. Hulver, Andrew A. Butler
Publikováno v:
Molecular Metabolism, Vol 4, Iss 4, Pp 310-324 (2015)
Objective: The peptide hormone adropin regulates fuel selection preferences in skeletal muscle under fed and fasted conditions. Here, we investigated whether adropin treatment can ameliorate the dysregulation of fuel substrate metabolism, and improve
Externí odkaz:
https://doaj.org/article/e7cdba64d42b4fcfb2e4d3b1a46dd86e
Autor:
Kellie A Kroscher, Dane W Fausnacht, Ryan P McMillan, Samer W El-Kadi, Emma H Wall, David M Bravo, Robert P Rhoads
Publikováno v:
Journal of Animal Science. 100
Substantial economic losses in animal agriculture result from animals experiencing heat stress (HS). Pigs are especially susceptible to HS, resulting in reductions in growth, altered body composition, and compromised substrate metabolism. In this stu
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bd8f53a245ef4c8a894f5e79b304a915
https://doi.org/10.1093/jas/skac195
https://doi.org/10.1093/jas/skac195