Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Ryan N. Montalvo"'
Autor:
Vivian Doerr, Ryan N. Montalvo, Branden L. Nguyen, Franccesco P. Boeno, Michael D. Sunshine, Victoria E. Bindi, David D. Fuller, Ashley J. Smuder
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 2073 (2022)
Cardiorespiratory dysfunction resulting from doxorubicin (DOX) chemotherapy treatment is a debilitating condition affecting cancer patient outcomes and quality of life. DOX treatment promotes cardiac and respiratory muscle pathology due to enhanced r
Externí odkaz:
https://doaj.org/article/302a7f5add414acba0a9f0e9d6742e6c
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 343 (2021)
Doxorubicin (DOX) is an anthracycline antibiotic used to treat a wide variety of hematological and solid tumor cancers. While DOX is highly effective at reducing tumor burden, its clinical use is limited by the development of adverse effects to both
Externí odkaz:
https://doaj.org/article/3a9bd7dfdcb34076b489c8f58bf3ae46
Autor:
Vivian Doerr, Ryan N. Montalvo, Oh Sung Kwon, Erin E. Talbert, Brian A. Hain, Fraser E. Houston, Ashley J. Smuder
Publikováno v:
Antioxidants, Vol 9, Iss 3, p 263 (2020)
Clinical use of the chemotherapeutic doxorubicin (DOX) promotes skeletal muscle atrophy and weakness, adversely affecting patient mobility and strength. Although the mechanisms responsible for DOX-induced skeletal muscle dysfunction remain unclear, s
Externí odkaz:
https://doaj.org/article/042030b606b44474ae51c4d5c162c0bf
Autor:
Smuder, Franccesco P. Boeno, Jay Patel, Ryan N. Montalvo, Stephanie S. Lapierre-Nguyen, Claire M. Schreiber, Ashley J.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10222
Doxorubicin (DOX) is a highly effective chemotherapy agent prescribed for cancer treatment. However, the clinical use of DOX is limited due to off-target toxicity in healthy tissues. In this regard, hepatic and renal metabolic clearance results in DO
Autor:
Cesar Eduardo Jacintho Moritz, Ryan N. Montalvo, Vivian Doerr, Branden L. Nguyen, Ashley J. Smuder
Publikováno v:
Physiology. 38
Doxorubicin (DOX) is a highly effective chemotherapeutic agent used in the treatment of a broad spectrum of human cancers. However, the clinical use of DOX is limited due to dose-dependent cardiotoxicity, which adversely affects quality of life and s
Autor:
Roman M, Natoli, Dimitrius P, Marinos, Ryan N, Montalvo, Yasmin, Degani, George, Ochenjele, Cullen, Griffith, Anthony, Ding, I Leah, Gitajn, Theodore T, Manson, Aaron J, Johnson, Birthe Veno, Kjellerup, Janette M, Harro, Manjari, Joshi, Robert V, O'Toole
Publikováno v:
Journal of Bone and Joint Surgery. 104:497-503
Next-generation DNA sequencing (NGS) detects bacteria-specific DNA corresponding to the 16S ribosomal RNA gene and can identify bacterial presence with greater accuracy than traditional culture methods. The clinical relevance of these findings is unk
Autor:
Vivian Doerr, Ryan N. Montalvo, Branden L. Nguyen, Franccesco P. Boeno, Mustafa Ozdemir, Matthew P. Bomkamp, Ashley J. Smuder
Publikováno v:
The FASEB Journal. 36
Autor:
Claude Sagi, Hrayr G Basmajian, Harsh R. Parikh, Robert V O'Toole, John Kark, Brian Miller, Brian P. Cunningham, Austin Heare, Ashley Ali, Bradley Reahl, Saif U Zaman, Giuliana Rotuno, William T. Obremskey, David W. Shearer, Ryan McLemore, Mark Bender, Ryan N Montalvo, Breanna L Blaschke
Publikováno v:
European Journal of Orthopaedic Surgery & Traumatology. 31:235-243
Subtrochanteric femur fractures associate with a relatively high complication rate and are traditionally treated operatively with a period of limited weight bearing. Transitioning from extramedullary to intramedullary implants, there are increasing b
Publikováno v:
American Journal of Physiology-Regulatory, Integrative and Comparative Physiology. 318:R227-R233
Doxorubicin (DOX) is a highly effective antineoplastic agent used in cancer treatment. Unfortunately, clinical use of DOX is limited due to the development of dose-dependent toxicity to cardiac and respiratory (i.e., diaphragm) muscles. After adminis
Autor:
Ryan N. Montalvo, Franccesco P. Boeno, Imtiaz M. Dowllah, Cesar E. Jacintho Moritz, Branden L. Nguyen, Vivian Doerr, Matthew P. Bomkamp, Ashley J. Smuder
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 9; Pages: 7689
Doxorubicin (DOX) is a chemotherapeutic agent highly effective at limiting cancer progression. Despite the efficacy of this anticancer drug, the clinical use of DOX is limited due to cardiotoxicity. The cardiac mitochondria are implicated as the prim