Zobrazeno 1 - 10
of 29
pro vyhledávání: '"Ryan N. Montalvo"'
Autor:
Franccesco P. Boeno, Jay Patel, Ryan N. Montalvo, Stephanie S. Lapierre-Nguyen, Claire M. Schreiber, Ashley J. Smuder
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 12, p 10222 (2023)
Doxorubicin (DOX) is a highly effective chemotherapy agent prescribed for cancer treatment. However, the clinical use of DOX is limited due to off-target toxicity in healthy tissues. In this regard, hepatic and renal metabolic clearance results in DO
Externí odkaz:
https://doaj.org/article/5462bc68012e4f1eb343b5f81e0b79e8
Autor:
Ryan N. Montalvo, Franccesco P. Boeno, Imtiaz M. Dowllah, Cesar E. Jacintho Moritz, Branden L. Nguyen, Vivian Doerr, Matthew P. Bomkamp, Ashley J. Smuder
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 9, p 7689 (2023)
Doxorubicin (DOX) is a chemotherapeutic agent highly effective at limiting cancer progression. Despite the efficacy of this anticancer drug, the clinical use of DOX is limited due to cardiotoxicity. The cardiac mitochondria are implicated as the prim
Externí odkaz:
https://doaj.org/article/32604241051144d49818a85b72913b75
Autor:
Vivian Doerr, Ryan N. Montalvo, Branden L. Nguyen, Franccesco P. Boeno, Michael D. Sunshine, Victoria E. Bindi, David D. Fuller, Ashley J. Smuder
Publikováno v:
Antioxidants, Vol 11, Iss 10, p 2073 (2022)
Cardiorespiratory dysfunction resulting from doxorubicin (DOX) chemotherapy treatment is a debilitating condition affecting cancer patient outcomes and quality of life. DOX treatment promotes cardiac and respiratory muscle pathology due to enhanced r
Externí odkaz:
https://doaj.org/article/302a7f5add414acba0a9f0e9d6742e6c
Publikováno v:
Antioxidants, Vol 10, Iss 3, p 343 (2021)
Doxorubicin (DOX) is an anthracycline antibiotic used to treat a wide variety of hematological and solid tumor cancers. While DOX is highly effective at reducing tumor burden, its clinical use is limited by the development of adverse effects to both
Externí odkaz:
https://doaj.org/article/3a9bd7dfdcb34076b489c8f58bf3ae46
Autor:
Ryan N. Montalvo, Vivian Doerr, Oh Sung Kwon, Erin E. Talbert, Jeung-Ki Yoo, Moon-Hyon Hwang, Branden L. Nguyen, Demetra D. Christou, Andreas N. Kavazis, Ashley J. Smuder
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 21, p 8105 (2020)
Doxorubicin (DOX) is a highly effective chemotherapeutic agent used in the treatment of various cancer types. Nevertheless, it is well known that DOX promotes the development of severe cardiovascular complications. Therefore, investigation into the u
Externí odkaz:
https://doaj.org/article/e97d49fc58974911904881bca2448476
Autor:
Vivian Doerr, Ryan N. Montalvo, Oh Sung Kwon, Erin E. Talbert, Brian A. Hain, Fraser E. Houston, Ashley J. Smuder
Publikováno v:
Antioxidants, Vol 9, Iss 3, p 263 (2020)
Clinical use of the chemotherapeutic doxorubicin (DOX) promotes skeletal muscle atrophy and weakness, adversely affecting patient mobility and strength. Although the mechanisms responsible for DOX-induced skeletal muscle dysfunction remain unclear, s
Externí odkaz:
https://doaj.org/article/042030b606b44474ae51c4d5c162c0bf
Autor:
Smuder, Franccesco P. Boeno, Jay Patel, Ryan N. Montalvo, Stephanie S. Lapierre-Nguyen, Claire M. Schreiber, Ashley J.
Publikováno v:
International Journal of Molecular Sciences; Volume 24; Issue 12; Pages: 10222
Doxorubicin (DOX) is a highly effective chemotherapy agent prescribed for cancer treatment. However, the clinical use of DOX is limited due to off-target toxicity in healthy tissues. In this regard, hepatic and renal metabolic clearance results in DO
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=multidiscipl::bc836855aeab45b69a42ae8afa94e0c5
Autor:
Cesar Eduardo Jacintho Moritz, Ryan N. Montalvo, Vivian Doerr, Branden L. Nguyen, Ashley J. Smuder
Publikováno v:
Physiology. 38
Doxorubicin (DOX) is a highly effective chemotherapeutic agent used in the treatment of a broad spectrum of human cancers. However, the clinical use of DOX is limited due to dose-dependent cardiotoxicity, which adversely affects quality of life and s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::28a3754d32bef945ab769341a0053ae8
https://doi.org/10.1152/physiol.2023.38.s1.5732546
https://doi.org/10.1152/physiol.2023.38.s1.5732546
Autor:
Roman M, Natoli, Dimitrius P, Marinos, Ryan N, Montalvo, Yasmin, Degani, George, Ochenjele, Cullen, Griffith, Anthony, Ding, I Leah, Gitajn, Theodore T, Manson, Aaron J, Johnson, Birthe Veno, Kjellerup, Janette M, Harro, Manjari, Joshi, Robert V, O'Toole
Publikováno v:
Journal of Bone and Joint Surgery. 104:497-503
Next-generation DNA sequencing (NGS) detects bacteria-specific DNA corresponding to the 16S ribosomal RNA gene and can identify bacterial presence with greater accuracy than traditional culture methods. The clinical relevance of these findings is unk
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6d3631235e311ed9990b95a35fd61da4
https://doi.org/10.2106/jbjs.21.00785
https://doi.org/10.2106/jbjs.21.00785
Autor:
Vivian Doerr, Ryan N. Montalvo, Branden L. Nguyen, Franccesco P. Boeno, Mustafa Ozdemir, Matthew P. Bomkamp, Ashley J. Smuder
Publikováno v:
The FASEB Journal. 36
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::abca2447bd656a4b70da165225b303fb
https://doi.org/10.1096/fasebj.2022.36.s1.r4909
https://doi.org/10.1096/fasebj.2022.36.s1.r4909