Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Ryan Mordue"'
Autor:
Stefano Grosso, Alberto Marini, Katarina Gyuraszova, Johan Vande Voorde, Aristeidis Sfakianos, Gavin D. Garland, Angela Rubio Tenor, Ryan Mordue, Tanya Chernova, Nobu Morone, Marco Sereno, Claire P. Smith, Leah Officer, Pooyeh Farahmand, Claire Rooney, David Sumpton, Madhumita Das, Ana Teodósio, Catherine Ficken, Maria Guerra Martin, Ruth V. Spriggs, Xiao-Ming Sun, Martin Bushell, Owen J. Sansom, Daniel Murphy, Marion MacFarlane, John P. C. Le Quesne, Anne E. Willis
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Treating malignant pleural mesothelioma (MpM) is challenging due to a lack of druggable genes, but other molecular features could be clinically useful. Here the authors profile mRNA translation dysregulation in MpM cell lines using polysome profiling
Externí odkaz:
https://doaj.org/article/7e118ded480445418fbb52706c703037
Autor:
Ryan Mordue, David Piñeiro, Anne E. Willis, Mark Stoneley, Jana Alexandrova, Rebekah Jukes-Jones
Publikováno v:
Biochemical Journal
NF-κB repressing factor (NKRF) was recently identified as an RNA binding protein that together with its associated proteins, the 5′–3′ exonuclease XRN2 and the helicase DHX15, is required to process the precursor ribosomal RNA. XRN2 is a multi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a849cdabbba01dc04e1f7aaca8969cfe
http://europepmc.org/articles/PMC7054742
http://europepmc.org/articles/PMC7054742
Autor:
Anne E. Willis, Ana Teodósio, Katarina Gyuraszova, Xiao-Ming Sun, Claire Smith, Ryan Mordue, Marco Sereno, Leah Officer, Claire Rooney, David Sumpton, Pooyeh Farahmand, Angela Rubio Tenor, Owen J. Sansom, Aristeidis P. Sfakianos, Johan Vande Voorde, Maria Guerra Martin, Gavin D. Garland, Madhumita Das, Ruth V. Spriggs, Tanya Chernova, Catherine Ficken, Alberto Marini, Marion MacFarlane, Daniel J. Murphy, Stefano Grosso, Nobu Morone, Martin Bushell, John Le Quesne
Publikováno v:
Nature Communications, Vol 12, Iss 1, Pp 1-17 (2021)
Nature Communications
Nature Communications
Malignant mesothelioma (MpM) is an aggressive, invariably fatal tumour that is causally linked with asbestos exposure. The disease primarily results from loss of tumour suppressor gene function and there are no ‘druggable’ driver oncogenes associ
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4634317d1a5eaacf6a942213133b30e4
https://eprints.gla.ac.uk/248582/1/248582.pdf
https://eprints.gla.ac.uk/248582/1/248582.pdf
Autor:
Mark Stoneley, Robert F. Harvey, Thomas E. Mulroney, Ryan Mordue, Rebekah Jukes-Jones, Kelvin Cain, Kathryn S. Lilley, Ritwick Sawarkar, Anne E. Willis
Publikováno v:
Molecular cell. 82(8)
During the translation surveillance mechanism known as ribosome-associated quality control, the ASC-1 complex (ASCC) disassembles ribosomes stalled on the mRNA. Here, we show that there are two distinct classes of stalled ribosome. Ribosomes stalled
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86d8275ebd1953f865cc26801f17dec5
https://pubmed.ncbi.nlm.nih.gov/35180429
https://pubmed.ncbi.nlm.nih.gov/35180429
Autor:
Manasa Ramakrishna, Aristeidis P. Sfakianos, Gavin D. Garland, Thomas E. Mulroney, Robert F. Harvey, Mariavittoria Pizzinga, Veronica Dezi, Tuija Pöyry, Ryan Mordue, Anne E. Willis, Mie Monti
Publikováno v:
WIREs RNA. 11
Following cell stress, a wide range of molecular pathways are initiated to orchestrate the stress response and enable adaptation to an environmental or intracellular perturbation. The post-transcriptional regulation strategies adopted during the stre
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::18e3c23cbed760762ee779506a68852d
https://doi.org/10.1002/wrna.1578
https://doi.org/10.1002/wrna.1578