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Autor:
Dario A. Gutierrez, Holly M. Horton, Troy Patterson, Robert Hofmeister, Julie Donaghey, Philippe Kieffer-Kwon, Jessica Gierut, Ryan Milione, Julio Gomez-Rodriguez, Robert Tighe, Tiffany Chan, Joshua Daniel
Publikováno v:
Cancer Research. 81:1514-1514
The natural T cell receptor (TCR) recognizes its cognate peptide antigen only when presented on human leukocyte antigen (HLA) molecules and requires HLA matching of α/β TCR-engineered T cells for cancer therapy. To bypass the need for HLA matching,