Zobrazeno 1 - 10
of 21
pro vyhledávání: '"Ryan Michalek"'
Autor:
Thomas K. Waddell, Licun Wu, Marc de Perrot, Shaf Keshavjee, Yidan D. Zhao, Lei Chu, Jenny Peng, Mingyao Liu, Li Yin, Ryan Michalek, John Granton, Hana Z. H. Yun
Publikováno v:
Metabolomics
Although multiple, complex molecular studies have been done for understanding the development and progression of pulmonary hypertension (PAH), little is known about the metabolic heterogeneity of PAH. Using a combination of high-throughput liquid-and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6cabc68052f912932bc85cb806ac7c7a
https://doi.org/10.1007/s11306-014-0653-y
https://doi.org/10.1007/s11306-014-0653-y
Autor:
Ryan Michalek, Valerie Gerriets, Amanda Nichols, Makoto Inoue, Barbara Theriot, Vincent Giguere, Donald McDonnell, Mari Shinohara, Julia Walker, Jeffrey Rathmell
Publikováno v:
The Journal of Immunology. 188:123.48-123.48
Upon activation, naïve CD4+ T cells differentiate into effector (Teff) subsets that provide protective immunity or inducible regulatory (Treg) subsets which balance inappropriate inflammation and autoimmunity. Consistent with distinct immunological
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b04e5f31607998c57e2e97938be7a20f
https://doi.org/10.4049/jimmunol.188.supp.123.48
https://doi.org/10.4049/jimmunol.188.supp.123.48
Autor:
Jeniffer Hernandez, Ryan Michalek, Brian Weist, Ryan Newton, Jose Limon, Mayra Carrillo, Elyse Paterson, Long Nguyen, David Fruman, Jeffrey Rathmell, Craig Walsh
Publikováno v:
The Journal of Immunology. 186:113.19-113.19
The delicate balance between effector T cells (Teff cells) and regulatory T cells (Treg cells) is crucial for preventing autoimmunity while maintaining efficient immune function. Mice deficient in the serine/threonine kinase, Dap Related Apoptosis in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::dda62dc513bf82694e8f0be5e7672980
https://doi.org/10.4049/jimmunol.186.supp.113.19
https://doi.org/10.4049/jimmunol.186.supp.113.19
Publikováno v:
The Journal of Immunology. 184:132.7-132.7
Upon both B and T cell activation the level of reactive oxygen intermediates (ROI) increases. Prior studies in the literature demonstrated that activated lymphocytes have increased total levels of surface free thiols, potentially as a compensatory me
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d0cb4b630d95747a7312d5de938e97ea
https://doi.org/10.4049/jimmunol.184.supp.132.7
https://doi.org/10.4049/jimmunol.184.supp.132.7
Autor:
Ryan Michalek, Sarah Jacobs, Ching-yi Chang, Olga Ilkayeva, Nancie Maciver, Russell Jones, Vincent Giguere, Donald McDonnell, Jeffrey Rathmell
Publikováno v:
The Journal of Immunology. 184:139.8-139.8
T lymphocyte activation initiates rapid cell growth and proliferation that is fueled by increased glucose metabolism. Molecular factors contributing to this transition and how metabolism impacts immunity, however, have remained uncertain. We have unc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e84580af7e9427532ae2d29082d7e248
https://doi.org/10.4049/jimmunol.184.supp.139.8
https://doi.org/10.4049/jimmunol.184.supp.139.8
Autor:
Mrinalini1 mrinali2@bio.rochester.edu, Siebert, Aisha2, Wright, Jeremy3, Martinson, Ellen1, Wheeler, David4, Werren, John1
Publikováno v:
Metabolomics. Apr2015, Vol. 11 Issue 2, p350-366. 17p.
Autor:
Zhao, Yidan yidanzhao@gmail.com, Yun, Hana1, Peng, Jenny1, Yin, Li1, Chu, Lei1, Wu, Licun1, Michalek, Ryan2, Liu, Mingyao1, Keshavjee, Shaf1, Waddell, Thomas1, Granton, John3, Perrot, Marc marc.deperrot@uhn.ca
Publikováno v:
Metabolomics. Dec2014, Vol. 10 Issue 6, p1169-1175. 7p.
Autor:
Gironès, Núria1,2 (AUTHOR) ngirones@cbm.csic.es, Carbajosa, Sofía1 (AUTHOR), Guerrero, Néstor A.1 (AUTHOR), Poveda, Cristina1 (AUTHOR), Chillón-Marinas, Carlos1 (AUTHOR), Fresno, Manuel1,2 (AUTHOR)
Publikováno v:
PLoS Neglected Tropical Diseases. 11/20/2014, Vol. 8 Issue 11, p1-11. 11p.
Autor:
Zhao, Yidan1 yidanzhao@gmail.com, Peng, Jenny1, Lu, Catherine1, Hsin, Michael1, Mura, Marco1, Wu, Licun1, Chu, Lei1, Zamel, Ricardo1, Machuca, Tiago1, Waddell, Thomas1, Liu, Mingyao1, Keshavjee, Shaf1, Granton, John1, de Perrot, Marc1 marc.deperrot@uhn.ca
Publikováno v:
PLoS ONE. Feb2014, Vol. 9 Issue 2, p1-11. 11p.