Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Ryan Michael Kelley"'
Autor:
John R. Soglia, Hao Sun, Jonathan N. Bauman, Zhuang Miao, Jianke Li, Angel Guzman-Perez, Kenneth J. DiRico, Tim F. Ryder, Scott W. Bagley, Kosea S. Frederick, Bruce M. Bechle, Sabrina X. Zhao, Michael P. Zawistoski, Daniel P. Walker, Kevin K.-C. Liu, Mary Theresa Didiuk, Amit S. Kalgutkar, Joel Morris, Robert M. Oliver, Ryan Michael Kelley, John William Benbow, David A. Griffith, Chandra Prakash
Publikováno v:
Chemical Research in Toxicology. 23:1115-1126
The synthesis and structure-activity relationship studies on 5-trifluoromethylpyrido[4,3-d]pyrimidin-4(3H)-ones as antagonists of the human calcium receptor (CaSR) have been recently disclosed [ Didiuk et al. ( 2009 ) Bioorg. Med. Chem. Lett. 19 , 45
Autor:
Scott W. Bagley, Hang T. Nguyen, Kosea S. Frederick, Michael P. Zawistoski, Kenneth J. DiRico, Vishwas M. Paralkar, Xiaojing Yang, Hua Gao, Thanh V. Olson, Keith Riccardi, Stephanie Santucci, F. Christopher Bi, Tristan S. Maurer, Matthew Corbett, Daniel P. Walker, Ryan Michael Kelley, Robert M. Oliver, John William Benbow, David R. Healy, Joseph DiBrinno, Amit S. Kalgutkar, Kevin K.-C. Liu, Mei Li, Syed Ahmed, Mary Theresa Didiuk, Joel Morris, Chiliu Chen, William M. Hungerford, Bruce M. Bechle, Yuan Zeng, Jianke Li, Angel Guzman-Perez, David A. Griffith
Publikováno v:
Bioorganic & Medicinal Chemistry Letters. 19:4555-4559
Synthesis and structure-activity relationship (SAR) studies on 5-trifluoromethylpyrido[4,3-d]pyrimidin-4(3H)-ones, a novel class of calcium receptor antagonists is described with particular emphasis on optimization of the pharmacokinetic/pharmacodyna