Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Ryan Mcguinness"'
Autor:
Ryan McGuinness
Publikováno v:
Cultural Economies of the Atlantic World
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::cd2482ffb5298bff7e71cf833d46e4a3
https://doi.org/10.4324/9781003025436-18
https://doi.org/10.4324/9781003025436-18
Autor:
Daniel J. Capon, Sue Klapholz, Joanna F. Hales, Michael Mendez, Catherine E. Maynard-Currie, Donna M. Louie, Hitoshi Sasai, Larry L. Green, Yongjun Zeng, Nathaniel E. David, Dan Garza, Ryan Mcguinness, Margaret C. Hardy, Aya Jakobovits, Hirohisa Tsuda, Douglas H. Smith, Hadi Abderrahim, Masato Noguchi, Daniel G. Brenner
Publikováno v:
Annals of the New York Academy of Sciences. 764:525-535
Our paper describes the introduction of large fragments of both the human heavy and light chain Ig genes into the mouse germline to create a mouse strain capable of producing a broad repertoire of antigen-specific, fully human antibodies. The human i
Autor:
Ryan McGuinness, H. Roger Tang, Julia M. Michelotti, Gordon Leung, Edward Verdonk, Vivian F. Liu
Publikováno v:
JALA: Journal of the Association for Laboratory Automation. 10:258-269
Cellular dielectric spectroscopy (CDS) provides realtime, label-free, universal measurements, enabling comprehensive pharmacological evaluation of cell surface receptors in living cells. The sensitivity of the measurement allows monitoring of ligand-
Autor:
Kay Limoli, Sridhar Reddy, Rukmini Pennathur-Das, Mitchell H. Finer, Deborah Farson, Ryan Mcguinness, Tom Dull, David F. Broad, Sayeh Jalali, Richard Lazar
Publikováno v:
The Journal of Gene Medicine. 1:195-209
Background The use of gene modified T lymphocytes for immunotherapy in a cancer or AIDS clinical trial requires an efficient, safe ex vivo method for modification of these cells at manufacturing scale. Since retroviruses have been shown to be a moder
Autor:
Ryan Mcguinness, Syed V. S. Kashmiri, James G. Mcarthur, Hyun-Sil Lee, Salil D. Patel, Patricia Horan Hand, Ying Ge, Mitchell H. Finer, Jeffrey Schlom
Publikováno v:
Human Gene Therapy. 10:165-173
A chimeric immune receptor consisting of an extracellular antigen-binding domain derived from the CC49 humanized single-chain antibody, linked to the CD3zeta signaling domain of the T cell receptor, was generated (CC49-zeta). This receptor binds to T
Publikováno v:
Psychological reports. 111(2)
This study identified the most frequently cited scholars across 28 leading multicultural textbooks used in the training of counselors and counseling psychologists. Four spheres or clusters of multicultural scholars were identified and were characteri
Autor:
Ryan McGuinness
Publikováno v:
Assay and drug development technologies. 7(2)
Autor:
Ryan McGuinness
Publikováno v:
Current opinion in pharmacology. 7(5)
Cell-based assays are continuing to grow in importance in the drug discovery workflow. Their early introduction holds the promise of limiting attrition in the later, more costly phases of the process. This article reviews recent advances in the devel
Autor:
Yen-Wen Chen, H. Roger Tang, Julia M. Michelotti, Krystal Johnson, Edward Verdonk, Gordon Leung, Vivian F. Liu, Ryan McGuinness
Publikováno v:
Assay and drug development technologies. 4(5)
The CellKey (MDS Sciex, South San Francisco, CA) system enables comprehensive pharmacological evaluation of cell surface receptors, including G-protein coupled receptors (GPCRs) and tyrosine kinase receptors, using adherent and suspension cell lines