Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Ryan Massopust"'
Publikováno v:
Scientific Reports, Vol 12, Iss 1, Pp 1-14 (2022)
Abstract miRNAs are necessary for neuromuscular junction (NMJ) health; however, little is known about the proteins required for their activity in this regard. We examined expression of Argonaute 2 (Ago2) and miRNA biogenesis genes in skeletal muscles
Externí odkaz:
https://doaj.org/article/b065b031509c4d699c399a108b785294
Autor:
Ryan Massopust, Devin Juros, Dillon Shapiro, Mikayla Lopes, Saptarsi M. Haldar, Thomas Taetzsch, Gregorio Valdez
Publikováno v:
Neurobiology of Disease, Vol 162, Iss , Pp 105583- (2022)
Amyotrophic Lateral Sclerosis (ALS) is a currently incurable disease that causes progressive motor neuron loss, paralysis and death. Skeletal muscle pathology occurs early during the course of ALS. It is characterized by impaired mitochondrial biogen
Externí odkaz:
https://doaj.org/article/fe367ea0873a4453aa9f1e9a88cad2ac
Argonaute 2 is lost from neuromuscular junctions affected with amyotrophic lateral sclerosis in SOD1
Publikováno v:
Scientific reports. 12(1)
miRNAs are necessary for neuromuscular junction (NMJ) health; however, little is known about the proteins required for their activity in this regard. We examined expression of Argonaute 2 (Ago2) and miRNA biogenesis genes in skeletal muscles during d