Zobrazeno 1 - 1
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pro vyhledávání: '"Ryan M. Scales"'
Autor:
John Ginn, Wenhu Zhan, Gang Lin, Roland A. Cooper, Philip J. Rosenthal, Rong Wang, Tzu-Tshin Wong, Patrick K Tumwebaze, Joseph Visone, Laura A. Kirkman, George Sukenick, Björn F.C. Kafsack, Judith I. Okoro, Pradeep K. Singh, Hao Zhang, Ryan M. Scales, Jacob C. Harris, Peter T. Meinke, Tierra Ouellette
Publikováno v:
Journal of Medicinal Chemistry. 62:6137-6145
The Plasmodium proteasome (Pf20S) emerged as a target for antimalarials. Pf20S inhibitors are active at multiple stages of the parasite life cycle and synergize with artemisinins, suggesting that Pf20S inhibitors have potential to be prophylactic, th